The Diagnostic Significance of Serum Troponin Levels Lambs with White Muscle Disease

Year 2018, Volume: 2 Issue: 2, 5 - 11, 24.12.2018

Yıldıray Basbugan , Nazmi Yüksek , Nuri Altuğ , Ebubekir Ceylan , İbrahim Hakkı Yörük , Zahit Tevfik Ağaoğlu

Abstract

Objective:This study was carried
out to determine the prognostic importance of troponin enzyme levels in lambs
with White Muscle Disease (WMD).

Materials and Methods:This study consisted of
50 male and female lambs aged 0-3 months old, 30 of which had clinical white
muscle disease (Group I) and 20 of which were healthy (Group II – Control
Group). Group I was composed of lambs that showed clinical symptoms of the
disease. The disease was also identified by laboratory analysis. The lambs in
this group were treated and the course of the disease was followed for 15 days.

Results:Compared with the
control group, the Group I before treatment results were as follows: AST, LDH,
CK, CK-MB, Troponin I and T (P<0.001) were high, while GSH-Px (P<0.001),
SOD (P<0.01), Se (P<0.01), Retinol and Tocopherol were low. Compared with
the control group, the Group I After Treatment results were as follows: AST,
CK, Troponin T (P<0.001) were high, LDH (P<0.01) was high and GSH-Px
(P<0.01) was low. Comparing Group I Before Treatment and After Treatment
results, AST, CK, CK-MB and Troponin I (P<0.001), as well as GSH-Px, SOD and
Se (P<0.01) were high. It was determined that LDH decreased and Tocopherol
increased. Whereas Vitamin D3 was determined to be insignificant in all three
groups, the levels of CK-MB, Troponin I, Retinol, SOD and Se were insignificant
in the After Treatment and control groups, and the Troponin T and retinol
values were measured to be insignificant in the Before Treatment and After
Treatment groups.

Conclusion:To conclude, measuring
the AST, CK, CK-MB, LDH values as well as Troponin can be an important
parameter for the identification and prognosis of WMD

Keywords

Lamb, White Muscle Disease, Cardiac Marker, Troponin

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