Fungal Peritonitis in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis: A Report of Three Cases

Year 2007, Volume: 1 Issue: 1, 42 - 45, 20.03.2007

Zeliha Koçak Tufan

Abstract

Fungal peritonitis is a serious complication for patients undergoing continuous ambulatory peritoneal dialysis (CAPD). This retrospective study evaluates the clinical findings and treatment of three patients with chronic renal failure undergoing CAPD and had fungal peritonitis episodes at least once. In all cases the agents, responsible for the peritonitis, were non-albicans Candida species; all three had history of bacterial peritonitis and were under antibiotic therapy; all of them also had co-morbid diseases like diabetes mellitus and congestive hearth failure. Other common findings were hipoalbuminemia and anemia. They responded well to intraperitoneal fluconazole therapy. In two patients, remaining catheter in situ caused recurrence of fungal peritonitis..

Keywords

Peritoneal dialysis, fungal peritonitis, candida

Fungal Peritonitis in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis: A Report of Three Cases

Abstract

Fungal peritonitis is a serious complication for patients undergoing continuous ambulatory peritoneal dialysis (CAPD). This retrospective study evaluates the clinical findings and treatment of three patients with chronic renal failure undergoing CAPD and had fungal peritonitis episodes at least once. In all cases the agents, responsible for the peritonitis, were non-albicans Candida species; all three had history of bacterial peritonitis and were under antibiotic therapy; all of them also had co-morbid diseases like diabetes mellitus and congestive hearth failure. Other common findings were hipoalbuminemia and anemia. They responded well to intraperitoneal fluconazole therapy. In two patients, remaining catheter in situ caused recurrence of fungal peritonitis..

Fungal peritonit (FP), sürekli ayaktan periton diyalizi (SAPD) programında olan kronik böbrek yetmezliği hastalarda nadir görülen, ancak fatal sonuçlanabilecek bir komplikasyondur. Biz bu çalışmamızda kliniğimizde izlediğimiz üç fungal peritonit vakasını ele aldık. Her üç olguda da etken non-albicans candida idi; bakteriyel peritonit nedeni ile antibiyotik tedavisi altında iken FP gelişmişti; bir önceki peritonit etkenleri gram negatif bakterilerdi; diabetes mellitus, konjestif kalp yetmezliği gibi eşlik eden dahili problemleri vardı. Hastalarda saptanan bir diğer ortak nokta hipoalbuminemi ve anemilerinin olması idi. Flukonazol ile yapılan intraperitoneal tedaviye yanıt alındı. Ancak periton diyaliz katateri çekilmediği takdirde fungal peritonitin tekrarladığı saptandı.

Keywords

Periton diyalizi, fungal peritonit, kandida

References

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