Consanguineous Marriage is Still a Risk Factor of Congenital Malformations in Sakarya-Turkey

Year 2008, Volume: 2 Issue: 2, 303 - 309, 27.07.2008

Sibel Serin Kiliçoğlu

Abstract

The purpose of this study is to provide an overview to risk factors of birth defects and to determine the general attitudes and behaviours of the pregnant women during pregnancy process in the region of Sakarya in Turkey. This is a definitive retrospective study carried out between 3rd April-2nd June 2007. The sample group of the normal child group is randomly selected from Sakarya Gynecology and Child Hospital and the sample group of the children with abnormalities is randomly selected from Canada Training and Research School in Sakarya. The data for the study was obtained by the means of the survey form prepared by the researchers. 230 families were included to the study. When we appreciate the relationship between the couples we see that 10.4% of group 1 and 30.4% of group 2 were married with relative. 4.3% of group 1 and 30.4% of group 2 were cross cousin marriage. There was a significant difference (p< 0.001) between the two groups. The results revealed differences between the sample groups of normal and faulty birth childrens parents in terms of consanguineous and non-consanguineous matings. Such a discussion, if joined widely by first step therapy medical doctors and midwive, can result in more coordinated and effective approaches to the prevention of environmentally provoked abnormalities through beter understanding of the nature and management of risk factors result in birth defects.

Keywords

Consanguinity, birth defects, pregnancy

Akraba Evliliği Türkiye Sakarya Bölgesindeki Konjenital Anomalilerin Hala Önemli Bir Nedenidir

Abstract

Çalışma doğumsal anomalilerde risk faktörlerini gözden geçirmek ve Türkiye Sakarya bölgesindeki gebe kadınların genel alışkanlıklar ve davranış biçimlerini belirlemek için düzenlenmiştir. 3 Nisan-2 Haziran 2007 tarihleri arasında tanımlayıcı retrospektif bir çalışma olarak planlandı. Sağlıklı çocuk grubu “Sakarya Kadın Doğum ve Çocuk Hastanesi’ne” başvuran hastalardan rasgele seçilirken (Grup 1), örnek grubu yine aynı bölgedeki “Kanada Eğitim ve Araştırma Okulu’ndan” anomalili çocuklar arasından rasgele oluşturuldu (Grup 2). Çalışmadaki veriler, araştırmacılar tarafından hazırlanan inceleme formları esas alınarak elde edildi. Çalışmaya bilgilendirilmiş onam formunu imzalayan 230 aile dahil edildi. Çiftler arasındaki akrabalık ilişkisi değerlendirildiğinde bu oran 1. grupta %10.4 oranında izlenirken 2. grupta %30.4 olarak bulundu. 1. grupta %4.3 olarak izlenen 1. derece kuzen evliliği, 2. grupta %9.5 olarak belirlendi ve iki grup arasında istatistiksel olarak anlamlı (p<0.001) değerlendirildi. Sağlıklı ve doğumsal anomalili grup çocuklarının ebeveynleri arasında akraba evliliği olan ve olmayan grup arasında anlamlı farklar vardır. Doğumsal anomalilerde risk faktörlerini daha iyi anlayabilmek, kontrol edebilmek ve çevresel faktörlerin tetiklediği anomalileri önleyebilmek için her şeyden önce tıp hekimleri ve hemşirelerin katılımıyla birinci basamak tedavi hizmetlerinde etkili koordine bir bakış açısında olunmalıdır.

Keywords

Kan bağı, doğumsal anomaliler, gebelik

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