Multiple Pulmonary Artery Aneurysms and Pulmonary Hypertension in a Patient with Takayasu Arteritis: Case Report and Review of Literature

Year 2009, Volume: 3 Issue: 1, 54 - 58, 19.03.2009

Gökhan Aykun

Abstract

Takayasu arteritis, also known as pulseless disease, is a rare inflammatory vascular disease which primarily affects the aorta and its major branches. Vessel inflammation leads to wall thickening, fibrosis and stenosis. More severe inflammation can destroy the arterial media and lead to aneurysm formation. The clinical features of this disease are quite variable, depending on the involvement location. Typical features relate to systemic arteries involvement. Although clinically systemic symptoms are more clear, pulmonary vasculary disease occurs in an important ratio of patients. But, it has been reported in little cases whose pulmonary vascular involvement is determining factor in prognosis. We present a patient who complains of dyspnea for 3 years, has established multiple Pulmonary artery aneurysms and widespread thrombosis in his peripheral arterial vessels and has been diagnosed as Takayasu arteritis.

Keywords

Takayasu arteritis; multiple pulmonary artery aneurysms; pulmonary hypertension

Multiple Pulmoner Arter Anevrizmaları ve Pulmoner Hipertansiyonu Olan Takayasu Arteritli Bir Hasta: Olgu Sunumu ve Literatür Derlemesi

Abstract

Nabızsızlık hastalığı olarak da bilinen Takayasu Arteriti, aort ve onun major dallarını tutan nadir görülen inflamatuar bir damar hastalığıdır. Damar inflamasyonu duvar kalınlaşması, fibrozis ve stenoza neden olur. Daha şiddetli inflamasyon arterin media tabakasını tahrip edebilir ve anevrizma gelişmesine neden olabilir. Klinik özellikleri, hastalığın tuttuğu yere göre tamamen farklılık gösterir. Tipik özellikleri sistemik arter tutulumuna bağlıdır. Hastalığın sistemik bulgularının klinik olarak daha belirgin olmasına karşın pulmoner vasküler tutulum hastaların önemli bir kısmında oluşur. Fakat pulmoner vasküler tutulumun prognozda belirleyici olduğu az sayıda vaka bildirilmiştir. Burada, 3 yıldır olan nefes darlığı şikayeti ile başvuran ve pulmoner hipertansiyon, multiple pulmoner arter anevrizmaları ve periferal arteryel damarlarında yaygın trombüsleri saptanan ve takayasu arteriti tanısı konulan bir olgu sunuldu.

Dr. Gökhan AYKUN, Dr. Ayşegül KARALEZLİ, Dr. Mükremin ER, Dr. H. Canan HASANOĞLU

Keywords

Takayasu arteriti; multiple pulmoner arter anevrizması; pulmoner hipertansiyon, Takayasu Arteritli, Arter Anevrizmaları

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