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Successful Treatment of Unruptured Cornual Pregnancy Usıng Intravenous Methotrexate: A Case Report

Year 2007, Volume: 14 Issue: 1, 65 - 67, 01.02.2007

Deniz Balsak Murat İnal Yusuf Yıldırım R. Soner Öner Şivekar Tınar

Abstract

Cornual pregnancy, which is unusual type of ectopic pregnancy, comprises 2-4% of all ectopic pregnancies. Its morbidity and mortality are directly related to the length of time before diagnosis. Early diagnosis and effective treatment are essential to prevent patient from poor outcome. This paper presents a case of a cornual pregnancy diagnosed in the 5th week of gestation. Intravenous double dose Methotrexate (50 mg/m2) was used successfully in the treatment and follow-up was carried out using transvaginal ultrasound and serial B-hCG estimations. Key words: Cornual pregnancy, Methotrexate

Keywords

Cornual pregnancy Methotrexate

References

  • Kerr LM, Anderson DF. Angular pregnancy: A clinical entity. Br Med J 1934; 1: 1113- 4
  • Moon HS, Choi IJ, Park YH, Vim SG. New simple endoscopic operations for interstitial pregnancies. Am J Obstet Gynecol 2000; 182: 114-21
  • Bond AL, Grifo JA, Chervenak FA. Term interstitial pregnancy with uterine torsion: sonographic, pathologic, and clinical findings. Obstet Gynecol 1989; 73: 857-9
  • Mattingly RF, Thompson JD. Te Lindes operative gynecology, 6th edition, Philadelphia: JP Lippincott, 1985; 439.
  • Robin M. F. van der Weiden Veronique H. M. Karsdorp. Recurrent cornual pregnancy after heterotopic cornual pregnancy successfully treated with systemic methotrexate. Arch Gynecol Obstet 2005; 273: 180-1
  • Maliha WE, Gonella P, Degnan EJ. Ruptured interstitial pregnancy presenting as an intrauterine pregnancy by ultrasound. Ann Emerg Med 1991; 20: 910-2
  • Brewer H, Gefroh S, Munkarah A, Hawkins R, Redman ME. Asymptomatic uterine rupture of a cornual pregnancy in the third trimester: a case report. J Reprod Med 2005; 50: 715-8
  • Coady DJ, Synder JR, Golstein SR. Ultrasound diagnosis of interstitial pregnancy. NY State J Med 1985; 85: 655-6
  • Jafri SZ, Loginsky SJ, Bouffard JA. Sonographic detection of interstitial pregnancy. JCU 1987; 15: 253-7
  • Chou MM, Tseng JJ, Yi YC, Chen WC, Ho ES. Diagnosis of an interstitial pregnancy with 4-dimensional volume contrast imaging. Am J Obstet Gynecol. 2005; 193: 1551- 3
  • Taylor KJW, Ramos IM, Feyock AL. Ectopic pregnancy: Duplex Doppler demonstration. Radiology 1989; 173: 93-7
  • Fernandez H, De Ziegler D, Bourget P, Feltain P, Frydman R. The place of methotrexate in the management of interstitial pregnancy. Hum Reprod 1991; 6: 302
  • Karsdorp VHM, Van der Veen F, Boer-Meisel ME, Kenemans P. Successful treatment with methotrexate of five interstiatial pregnancies. Hum Reprod 1992; 7: 1164-9
  • Voight R.R, van der Veen F, Karsdorp VHM, Hogerzeil HV, Ketting BW. Treatment of interstitial pregnancy with methotrexate: report of an unsuccessful case. Hum Reprod 1994; 9: 1576 -9
  • Donnez J, Nisolle M. Endoscopic management of ectopic pregnancy. Baillieres Clinical Obstetrics and Gynaecology 1994; 8: 707 -22
  • Gezer A, Mutlu H. Laparoscopic management of cornual pregnancy without sutures: Arch Gynecol Obstet 2004; 270: 194-6
  • Y Morita, O Tsutsumi, M Momoeda, Y Taketani. Cornual pregnancy successfully treated laparoscopically with fibrin glue hemostasis. The American College of Obstetricians and Gynecologists 1997; 90: 685-7
  • Reich H, Johns DA, DeCaprio J, McGlynn F, Reich E. Laparoscopic treatment of 109 consecutive ectopic pregnancies. J Reprod Med 1988; 33: 885-90
  • Tulandi T, Vilos G, Gomel V. Laparoscopic treatment of interstitial pregnancy: Obstet Gynecol 1995; 85: 465 -7
  • Katz S and Lurie S. Laparoscopic cornuostomy in the treatment of interstitial pregnancy with subsequent hysterosalpingography. Br J Gynaecol Obstet 1997; 104: 955-6
  • Dilbaz S, Katas B, Demir B, Dilbaz B. Treating cornual pregnancy with a single methotrexate injection: a report of 3 cases. J Reprod Med 2005; 50: 141-4
  • Karen Jermy, James Thomas, Alex Doo, Tom Bourne. The conservative management of interstitial pregnancy. BJOG 2004; 111: 1283-8

Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu

Year 2007, Volume: 14 Issue: 1, 65 - 67, 01.02.2007

Deniz Balsak Murat İnal Yusuf Yıldırım R. Soner Öner Şivekar Tınar

Abstract

Ektopik gebeliğin sık karşılaşılmayan bir tipi olan kornual gebelik, tüm ektopik gebelik olgularının %2-4'ünü oluşturmaktadır. Morbidite ve mortalitesi direkt olarak tanıdan önce geçen sürenin uzunluğu ile ilişkilidir. Hastayı kötü sonuçtan korumada erken tanı ve etkili tedavi esasdır. Bu makalede amaç 5. gebelik haftasında tanı alan bir kornual gebelik vakasını sunmaktadır. Tedavide intravenöz çift doz Methotrexate (50 mg/m2) başarıyla kullanıldı ve izlem transvajinal ultrason ve seri B-hCG ölçümleri ile gerçekleştirildi. Anahtar kelimeler: Kornual gebelik, Methotrexate

Keywords

Kornual gebelik Methotrexate

References

  • Kerr LM, Anderson DF. Angular pregnancy: A clinical entity. Br Med J 1934; 1: 1113- 4
  • Moon HS, Choi IJ, Park YH, Vim SG. New simple endoscopic operations for interstitial pregnancies. Am J Obstet Gynecol 2000; 182: 114-21
  • Bond AL, Grifo JA, Chervenak FA. Term interstitial pregnancy with uterine torsion: sonographic, pathologic, and clinical findings. Obstet Gynecol 1989; 73: 857-9
  • Mattingly RF, Thompson JD. Te Lindes operative gynecology, 6th edition, Philadelphia: JP Lippincott, 1985; 439.
  • Robin M. F. van der Weiden Veronique H. M. Karsdorp. Recurrent cornual pregnancy after heterotopic cornual pregnancy successfully treated with systemic methotrexate. Arch Gynecol Obstet 2005; 273: 180-1
  • Maliha WE, Gonella P, Degnan EJ. Ruptured interstitial pregnancy presenting as an intrauterine pregnancy by ultrasound. Ann Emerg Med 1991; 20: 910-2
  • Brewer H, Gefroh S, Munkarah A, Hawkins R, Redman ME. Asymptomatic uterine rupture of a cornual pregnancy in the third trimester: a case report. J Reprod Med 2005; 50: 715-8
  • Coady DJ, Synder JR, Golstein SR. Ultrasound diagnosis of interstitial pregnancy. NY State J Med 1985; 85: 655-6
  • Jafri SZ, Loginsky SJ, Bouffard JA. Sonographic detection of interstitial pregnancy. JCU 1987; 15: 253-7
  • Chou MM, Tseng JJ, Yi YC, Chen WC, Ho ES. Diagnosis of an interstitial pregnancy with 4-dimensional volume contrast imaging. Am J Obstet Gynecol. 2005; 193: 1551- 3
  • Taylor KJW, Ramos IM, Feyock AL. Ectopic pregnancy: Duplex Doppler demonstration. Radiology 1989; 173: 93-7
  • Fernandez H, De Ziegler D, Bourget P, Feltain P, Frydman R. The place of methotrexate in the management of interstitial pregnancy. Hum Reprod 1991; 6: 302
  • Karsdorp VHM, Van der Veen F, Boer-Meisel ME, Kenemans P. Successful treatment with methotrexate of five interstiatial pregnancies. Hum Reprod 1992; 7: 1164-9
  • Voight R.R, van der Veen F, Karsdorp VHM, Hogerzeil HV, Ketting BW. Treatment of interstitial pregnancy with methotrexate: report of an unsuccessful case. Hum Reprod 1994; 9: 1576 -9
  • Donnez J, Nisolle M. Endoscopic management of ectopic pregnancy. Baillieres Clinical Obstetrics and Gynaecology 1994; 8: 707 -22
  • Gezer A, Mutlu H. Laparoscopic management of cornual pregnancy without sutures: Arch Gynecol Obstet 2004; 270: 194-6
  • Y Morita, O Tsutsumi, M Momoeda, Y Taketani. Cornual pregnancy successfully treated laparoscopically with fibrin glue hemostasis. The American College of Obstetricians and Gynecologists 1997; 90: 685-7
  • Reich H, Johns DA, DeCaprio J, McGlynn F, Reich E. Laparoscopic treatment of 109 consecutive ectopic pregnancies. J Reprod Med 1988; 33: 885-90
  • Tulandi T, Vilos G, Gomel V. Laparoscopic treatment of interstitial pregnancy: Obstet Gynecol 1995; 85: 465 -7
  • Katz S and Lurie S. Laparoscopic cornuostomy in the treatment of interstitial pregnancy with subsequent hysterosalpingography. Br J Gynaecol Obstet 1997; 104: 955-6
  • Dilbaz S, Katas B, Demir B, Dilbaz B. Treating cornual pregnancy with a single methotrexate injection: a report of 3 cases. J Reprod Med 2005; 50: 141-4
  • Karen Jermy, James Thomas, Alex Doo, Tom Bourne. The conservative management of interstitial pregnancy. BJOG 2004; 111: 1283-8
There are 22 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Deniz Balsak This is me

Murat İnal This is me

Yusuf Yıldırım This is me

R. Soner Öner This is me

Şivekar Tınar This is me

Publication Date February 1, 2007
Published in Issue Year 2007 Volume: 14 Issue: 1

Cite

APA Balsak, D., İnal, M., Yıldırım, Y., Öner, R. S., et al. (2007). Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu. Journal of Turgut Ozal Medical Center, 14(1), 65-67.
AMA Balsak D, İnal M, Yıldırım Y, Öner RS, Tınar Ş. Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu. J Turgut Ozal Med Cent. February 2007;14(1):65-67.
Chicago Balsak, Deniz, Murat İnal, Yusuf Yıldırım, R. Soner Öner, and Şivekar Tınar. “Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu”. Journal of Turgut Ozal Medical Center 14, no. 1 (February 2007): 65-67.
EndNote Balsak D, İnal M, Yıldırım Y, Öner RS, Tınar Ş (February 1, 2007) Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu. Journal of Turgut Ozal Medical Center 14 1 65–67.
IEEE D. Balsak, M. İnal, Y. Yıldırım, R. S. Öner, and Ş. Tınar, “Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu”, J Turgut Ozal Med Cent, vol. 14, no. 1, pp. 65–67, 2007.
ISNAD Balsak, Deniz et al. “Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu”. Journal of Turgut Ozal Medical Center 14/1 (February 2007), 65-67.
JAMA Balsak D, İnal M, Yıldırım Y, Öner RS, Tınar Ş. Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu. J Turgut Ozal Med Cent. 2007;14:65–67.
MLA Balsak, Deniz et al. “Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu”. Journal of Turgut Ozal Medical Center, vol. 14, no. 1, 2007, pp. 65-67.
Vancouver Balsak D, İnal M, Yıldırım Y, Öner RS, Tınar Ş. Rüptüre Olmamış Kornual Gebeliğin İntravenöz Methotrexate İle Başarılı Tedavisi: Olgu Sunumu. J Turgut Ozal Med Cent. 2007;14(1):65-7.