Abstract
Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease. Its manifestations are protean and virtually any organ system can be involved. The disease in children is generally more acute and more severe than that in adult. Recently it has been notified that intravenous immunoglobulins (IVIG) in patients with cerebral lupus have improved fairly. In this report, we present a case of systemic lupus erythematosus involving multiple organ systems, including psychosis which did not respond to high-dose intravenous corticosteroid therapy. After application of IVIG (400 mg/kg/24 hr, 5 day/month) as an adjunctive agent, psychosis of the patient was completely improved. This report supports the finding that IVIG therapy may successfully be used for nonresponders to conventional treatments of SLE, especially for those with cerebral complications. Key words: Systemic Lupus Erythematosus, immunoglobulins, child.
Abstract
Sistemik lupus eritematosus (SLE) otoimmun bir mu/tisistem hastalığıdır. Belirtileri çok yönlüdür ve hemen her organı tutabilir. SLE genellikle çocuklarda erişkinlerden daha akut başlar ve ağır seyreder. Son zamanlarda serebral lupuslu hastalarda intravenöz immunglobülinlerh oldukça iyi sonuçlar verdiği bildirilmektedir. Bu makalede, psikoz ve birden fazla organ tutulumu olan; yüksek doz intravenöz kortikosteroide yani vermeyen, IVIG uygulamasını takiben (400 mg/kg/gün, 5 gün/ay) psikoz tablosu tamamen düzelen bir SLE olgusu sunuldu. Bu bulgu, IVIG'in SLE'nin konvansiyonel tedavisine yamt vemeyen olgularda, özellikle de serebral lupus da başarılı bir şekilde kullanılabileceğin desteklemektedir. Anahtar kelimeler: Sistemik lupus eritematosus, intravenöz immunglobülin, çocuk
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | August 1, 1998 |
| Published in Issue | Year 1998 Volume: 5 Issue: 4 |