İleri evre epitelyal over kanserinde neoadjuvan kemoterapi ve interval sitoredüktif cerrahi

Year 2017, Volume: 20 Issue: 3, 9 - 15, 04.08.2019

Murat Öz , İlker Selçuk , Zeliha Fırat Cüylan , Hüseyin Akıllı Ali Ayhan

Abstract

Epitelyal over kanseri (EOK), fallop tüpü kanseri
(FTK) ya da primer peritoneal kanser (PPK) hastalarının büyük bölümü ileri
evrede tanı almaktadır. İleri evre hastalıkta standart yaklaşım primer
sitoredüktif cerrahi (SRC) ve takibinde platin tabanlı intravenöz
kemoterapidir. NAKT- interval SRC’den esas beklenti onkolojik sonuçları
değiştirmeden azalmış tümör yüküne bağlı olarak cerrahi morbiditeyi ve agresif
üst batın cerrahisi ihtiyacını azaltabilmektir. Bu derlemede ileri evre EOK
yönetiminde NAKT ile ilgili çalışmalar yöntemin etkinliği, hasta seçim
yöntemleri, yaşam kalitesi ve maliyet etkinlik konularında irdelenmiştir.

Keywords

epitelyal over kanseri, neoadjuvan kemoterapi

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