An exceptional survival term in primary neuroendocrine carcinoma of the vagina

Year 2018, Volume: 21 Issue: 1, 24 - 25, 06.12.2019

Malek Bouhani Zemni İnes Yasmine Ayari Mohamed Amine Bouida Riadh Chargui Khaled Rahal

Abstract

Introduction: Primary vaginal malignant tumors are rare, especially
neuroendocrine tumors. The primary small cell carcinoma of the vagina is an
aggressive tumor with poor prognosis because of early recurrence and
metastasis.

Aim:  to report the complexity of treatment of primary
neuroendocrine carcinoma of vagina, and its metastasis.

Material &methods: we report a retrospective case of primary
neuroendocrine carcinoma of vagina treated in our institution.

Results:  We report a case of a
37-year-old woman who was diagnosed with a small cell carcinoma of the vagina
without distant metastasis. The primary vaginal tumor was treated by surgery,
brachytherapy, and chemotherapy. The first recurrence appeared seven years after
initial diagnosis, which was a pulmonary metastasis, treated surgically. Seven
years after this recurrence, she was treated with chemotherapy and surgery for
another pulmonary metastasis. Fifteen years after the initial diagnosis, the
patient underwent surgery for brain
metastasis. She died eighteen months after the third recurrence.

Conclusions: This case splendidly illustrates a long
survival term of a tumor known with poor prognosis.

Keywords

Carcinoma, Neuroendocrine, survival, vagina

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