turk j diab obes Turkish Journal of Diabetes and Obesity 2587-0335 2587-0572 Zonguldak Bulent Ecevit University Endocrinology Gastroenterology and Hepatology ​Internal Diseases Endokrinoloji Gastroenteroloji ve Hepatoloji İç Hastalıkları Obez Hastalarda Alkole Bağlı Olmayan Yağlı Karaciğer Hastalığı (NAFLD) Prevalansı: Fibrozis-4 (FIB-4) İndeksi ve Aspartat Aminotransferaz/Trombosit Oranı (APRI) Skorlarının Karşılaştırmalı Değerlendirmesi Prevalence of Non-Alcoholic Fatty Liver Disease in Obese Patients: Comparative Evaluation of the Fibrosis-4 (FIB-4) Index and Aspartate Aminotransferase to Platelet Ratio Index (APRI) https://orcid.org/0000-0001-5535-1674 Açmaz Banu Kayseri City Hospital, Kayseri https://orcid.org/0000-0003-0909-7024 Bahçebaşı Sami Kayseri City Hospital, Kayseri https://orcid.org/0000-0001-8762-2571 Biçer Nazmiye Serap Kayseri City Hospital, Kayseri https://orcid.org/0009-0000-7470-2273 Biçer İfakat İrem Kayseri City Hospital, Kayseri https://orcid.org/0009-0001-5043-278X Aydın Erdem Kayseri City Hospital, Kayseri https://orcid.org/0009-0004-1093-4824 Türkmen Mehmet Yasin Kayseri City Hospital, Kayseri https://orcid.org/0000-0002-9637-6744 Bayram Fahri Department of Endocrinology and Metabolism, Faculty of Medicine, Erciyes University, Kayseri https://orcid.org/0000-0002-9309-7715 Sönmez Alper Department of Endocrinology, Güven Hospital, Ankara, Turkey 12 31 2025 9 3 298 306 10 13 2025 12 09 2025 Copyright © 2017, Turkish Journal of Diabetes and Obesity 2017 Turkish Journal of Diabetes and Obesity

Amaç: Obezite tanılı olgularda alkole bağlı olmayan yağlı karaciğer hastalığı (NAFLD) sık görülmekte, ancak klinik farkındalık vetarama oranı düşüktür. Bu çalışma, obezite kliniğinde ultrasonografi (US) kullanım sıklığını ve APRI ile FIB-4 skorlarının hepatiksteatozla ilişkisini değerlendirmeyi amaçlamaktadır.Gereç ve Yöntemler: Retrospektif, kesitsel tasarımla bir yıl içinde değerlendirilen 1.420 erişkin çalışmaya dahil edildi. Klinik velaboratuvar verileri dosya kayıtlarından elde edildi. Önceden klinik endikasyonlarla yapılmış 367 US raporu incelendi. Fibrozis riski,FIB-4 ≥1,3 ve APRI ≥1 olarak tanımlandı.Bulgular: US raporu bulunan hastaların oranı %25,8 olup, %63,2’sinde hepatik steatoz saptandı. APRI ≥1 tüm kohortun %31,1’inifibrozis riski altında sınıflandırırken, FIB-4 ≥1,3 yalnızca %3,5’ini belirledi. APRI değerleri BKİ ve glisemik durumdan bağımsızdıancak steatoz varlığında daha yüksekti (p

Aim: Non-alcoholic fatty liver disease (NAFLD) is common among individuals with obesity, yet clinical screening remains inadequate.This study aimed to assess ultrasonography (US) utilization and the relationship between APRI and FIB-4 scores and hepatic steatosisin an obesity-clinic population.Material and Methods: This retrospective single-center cross-sectional study included 1,420 adults evaluated over one year. Clinicaland laboratory data were retrieved from medical records. Previous abdominal US reports were available for 367 patients. Fibrosis riskwas defined as FIB-4 ≥1.3 and APRI ≥1. Group comparisons were performed using Kruskal–Wallis, Mann–Whitney U, and Chi-squaretests, and normality was assessed with the Shapiro–Wilk test. Results: US was available in 25.8% of patients, and hepatic steatosis was detected in 63.2% of those examined. APRI ≥1 classified 31.1%of the cohort at fibrosis risk, whereas FIB-4 ≥1.3 identified only 3.5%. APRI values were independent of BMI and glycemic status butwere higher in patients with steatosis (p

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