<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article  article-type="research-article"        dtd-version="1.4">
            <front>

                <journal-meta>
                                                                <journal-id>turk j diab obes</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Turkish Journal of Diabetes and Obesity</journal-title>
            </journal-title-group>
                            <issn pub-type="ppub">2587-0335</issn>
                                        <issn pub-type="epub">2587-0572</issn>
                                                                                            <publisher>
                    <publisher-name>Zonguldak Bulent Ecevit University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.25048/tudod.666059</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Health Care Administration</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Sağlık Kurumları Yönetimi</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <trans-title-group xml:lang="en">
                                    <trans-title>Prevalence of Symptomatic Cholelithiasis After Obesity Surgery and Timing of Surgical Treatment</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>Obezite Cerrahisi Sonrası Semptomatik Kolelitiazis Gelişme Sıklığı ve Cerrahi Tedavide Zamanlama</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-0085-2380</contrib-id>
                                                                <name>
                                    <surname>Kocaöz</surname>
                                    <given-names>Servet</given-names>
                                </name>
                                                                    <aff>ANKARA ATATÜRK EĞİTİM VE ARAŞTIRMA HASTANESİ, GENEL CERRAHİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-1936-4483</contrib-id>
                                                                <name>
                                    <surname>Yılmaz</surname>
                                    <given-names>Abdurrezzak</given-names>
                                </name>
                                                                    <aff>Ankara Şehir Hastanesi</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-5957-1770</contrib-id>
                                                                <name>
                                    <surname>Gemcioğlu</surname>
                                    <given-names>Emin</given-names>
                                </name>
                                                                    <aff>Ankara Şehir Hastanesi, İç Hastalıkları ABD</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-4704-5295</contrib-id>
                                                                <name>
                                    <surname>Parlak</surname>
                                    <given-names>Ömer</given-names>
                                </name>
                                                                    <aff>ANKARA YILDIRIM BEYAZIT ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20201229">
                    <day>12</day>
                    <month>29</month>
                    <year>2020</year>
                </pub-date>
                                        <volume>4</volume>
                                        <issue>3</issue>
                                        <fpage>244</fpage>
                                        <lpage>248</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20191227">
                        <day>12</day>
                        <month>27</month>
                        <year>2019</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20201127">
                        <day>11</day>
                        <month>27</month>
                        <year>2020</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2017, Turkish Journal of Diabetes and Obesity</copyright-statement>
                    <copyright-year>2017</copyright-year>
                    <copyright-holder>Turkish Journal of Diabetes and Obesity</copyright-holder>
                </permissions>
            
                                                                                                <trans-abstract xml:lang="en">
                            <p>Aim: 13% of adults are 18 years old and over, and comorbid diseases of obesity are on the increase in the World. Patients that reachstandard weight after bariatric surgery show recovery in comorbid diseases. Gallbladder stone incidence rate increases with obesity.Development of stone after bariatric surgery is known to be on higher levels, as well. The objective of this study is to analyze thegallbladder stone and/or complications that may develop after Laparoscopic Sleeve Gastrectomy (LSG) surgery.Material and Methods: The medical files of 68 patients were retrospectively analyzed, who underwent LSG surgery between January2013 and December 2016 in Ankara Atatürk Training and Research Hospital.Results: The age average of female patients that underwent LSG surgery is 42.95±10.72, while it is 36.23±10.76 for male patients. Whilethe mean BMI (Body Mass Index) of female and male patients were respectively 45.26±3.58 kg/m2 and 47.58±7.74 kg/m2, this mean wasfound that BMI levels decreased to 27.18±2.80 kg/m2 for female patients and 27.92±3.79 kg/m2 for male patients (p&amp;lt;0.001). 17 (31%) ofthe patients, who underwent LSG surgery suffered from gallbladder stone or sludge. Acute cholecystitis was found in one (5.88%) of thepatients who developed post-operative gallbladder stones. When the patients after LSG surgery were compared in terms of weight loss,no statistically significant difference was found between those with and without gallstones (p=0.065).Conclusion: Laparoscopic cholecystectomy (LC) was not required in patients who did not have symptomatic cholelithiasis. The rateof developing gallbladder stone after LSG surgery was found to be high. However, since these stones do not show any symptoms in theearly period, we think that regular control of LSG patients will decrease the incidence of symptomatic cholelithiasis.</p></trans-abstract>
                                                                                                                                    <abstract><p>Amaç: Dünya’da 18 yaş ve üzeri yetişkinlerin %13’ü obez olup, obeziteye komorbid hastalıklar da artmaktadır. Obezite cerrahisi sonrasınormal kiloya ulaşan hastalarda komorbid hastalıklarda iyileşme gözlenmektedir. Obezite ile safra kesesinde taş oluşumu insidansıartmaktadır. Obezite cerrahisi sonrasında yeni taş gelişimi de yüksek oranlarda bildirilmektedir. Bu çalışmada Laparoskopik SleeveGastrektomi (LSG) ameliyatı sonrası gelişebilecek safra kesesi taşı ve/veya komplikasyonlarının değerlendirilmesi amaçlanmıştır.Gereç ve Yöntemler: Ankara Atatürk Eğitim ve Araştırma Hastanesinde Ocak 2013 ile Aralık 2016 yılları arasında LSG ameliyatıyapılan 68 hastanın dosyası retrospektif olarak incelendi.Bulgular: LSG ameliyatı olan kadın hastaların ortalama yaşı 42,95±10,72 yıl, erkek hastaların ortalama yaşı 36,23±10,76 yıldır. Ameliyatöncesi kadın hastalarda vücut kütle indeksi (VKİ) ortalaması 45,26±3,58 kg/m2, erkeklerde 47,58±7,74 kg/m2 iken ameliyattan iki yılsonrasında VKİ ortalaması kadınlarda 27,18±2,80 kg/m2, erkeklerde 27,92±3,79 kg/m2 ye düştüğü saptandı (p&amp;lt;0,001). LSG operasyonugeçiren hastaların 17(%31)’sinde safra kesesi taşı veya çamuru saptandı. Postoperatif safra kesesi taşı gelişen hastalardan birisinde(%5,88) akut kolesistit geliştiği bulundu. LSG ameliyatı sonrası hastalar kilo kaybı açısından karşılaştırıldıklarında safra taşı gelişen vegelişmeyenler arasında istatistiksel olarak anlamlı bir farklılık saptanmadı (p=0,065).Sonuç: LSG ameliyatı yapılacak hastalardan semptomatik kolelitiazis şikayeti olmayan hastalara laparoskopik kolesistektomi (LK)yapılması gerekmedi. LSG ameliyatı sonrası safra kesesinde yeni taş gelişmesi yüksek oranda bulundu. Bununla birlikte bu taşlar erkendönemde semptom vermediği için LSG hastalarının düzenli kontrolünün yapılmasının semptomatik kolelitiazis insidansını azaltacağıkanaatindeyiz.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>Morbid Obezite</kwd>
                                                    <kwd>  Laporoskopik Sleeve Gastrektomi</kwd>
                                                    <kwd>  Safra Kesesi Taşları</kwd>
                                                    <kwd>  Kolesistektomi</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="en">
                                                    <kwd>Morbid obesity</kwd>
                                                    <kwd>  Laparoscopic sleeve gastrectomy</kwd>
                                                    <kwd>  Gallstones</kwd>
                                                    <kwd>  Cholecystectomy</kwd>
                                            </kwd-group>
                                                                                                                                        </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">1. World Health Organization. Obesity and overweight [Internet]. 2018 Feb 16; [cited 2018 August 30]. Available from: http://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight.
2. Republic of Turkey Ministry of Health. The Ministry of Health of Turkey, health statistics year book 2016. Ankara: SB-SAGEM-2017; [cited 2018 August 30]. Available from: http://ohsad.org/wp-content/uploads/2017/12/13160.pdf.
3. Kiriakopoulos A, Varounis C, Tsakayannis D, Linos D. Laparoscopic sleeve gastrectomy in morbidly obese patients. Technique and short term results. Hormones (Athens). 2009 Apr-Jun;8(2):138-43.
4. Eisenberg D, Bellatorre A, Bellatorre N. Sleeve gastrectomy as a stand-alone bariatric operation for severe, morbid, and super obesity. JSLS. 2013 Jan-Mar;17(1):63-7.
5. Al Zabadi H, Daqour A, Hawari A, Hasouni J. Short-term outcomes of laparoscopic sleeve gastrectomy among obesity patients in the Northern West Bank: a retrospective records review. BMC Res Notes. 2014 Feb 7;7:85.
6. Young MT, Gebhart A, Phelan MJ, Nguyen NT. Use and Outcomes of Laparoscopic Sleeve Gastrectomy vs Laparoscopic Gastric Bypass: Analysis of the American College of Surgeons NSQIP. J Am Coll Surg. 2015 May;220(5):880-5.
7. Våge V, Sande VA, Mellgren G, Laukeland C, Behme J, Andersen JR. Changes in obesity-related diseases and biochemical variables after laparoscopic sleeve gastrectomy: a two-year follow-up study. BMC Surg. 2014 Feb 11;14:8.
8. Dittrick GW, Thompson JS, Campos D, Bremers D, Sudan D. Gallbladder pathology in morbid obesity. Obesity Surgery. 2005;15(2):238–242.
9. Eleni S, Dimitris Z, Eleni Z, Dimitris P, Ourania P, Georgia K, George T. Complicated Gallstones after Laparoscopic Sleeve Gastrectomy. Hindawi Publishing Corporation Journal of Obesity Volume 2014, Article ID 468203, 5.
10. Li VK, Pulido N, Fajnwaks P, et al. Erratum to “Predictors of gallstone formation after bariatric surgery: a multivariate analysis of risk factors comparing gastric bypass, gastric banding, and sleeve gastrectomy” Surgical Endoscopy. 2009;23(7):p. 1645.
11. Quesada BM, Kohan G, Roff HE, Canullan CM, Chiappetta Porras LT. Management of gallstones and gallbladder disease in patients undergoing gastric bypass. World J Gastroenterol 2010; 16: 2075-9.
12. M. L. Shiffman, H. J. Sugerman, J. M. Kellum, W. H. Brewer, and E. W. Moore, “Gallstone formation after rapid weight loss: a prospective study in patients undergoing gastric bypass surgery for treatment of morbid obesity,” The American Journal of Gastroenterology, vol. 86, no. 8, pp. 1000–1005, 1991.
13. Coşkun H, Hasbahçeci M, Bozkurt S, Çipe G, Malya FÜ, Memmi N et al. Is concomitant cholecystectomy with laparoscopic sleeve gastrectomy safe? Turk J Gastroenterol. 2014 Dec;25(6):624-7.
14. Erlinger S. Gallstones in obesity and weight loss. Eur J Gastroenterol Hepatol. 2000 Dec;12(12):1347-52.
15. Iglézias Brandão de Oliveira C, Adami Chaim E, da Silva BB. Impact of rapid weight reduction on risk of cholelithiasis after bariatric surgery. Obes Surg. 2003 Aug;13(4):625-8.
16. Manatsathit W, Leelasinjaroen P, Al-Hamid H, Szpunar S, Hawasli A. The incidence of cholelithiasis after sleeve gastrectomy and its association with weight loss: A two-centre retrospective cohort study. Int J Surg. 2016 Jun;30:13-8.
17. Li VK, Pulido N, Martinez-Suartez P, Fajnwaks P, Jin HY, Szomstein S, Rosenthal RJ. Symptomatic gallstones after sleeve gastrectomy. Surg Endosc. 2009 Nov;23(11):2488-92.
18. Hasan MY, Lomanto D, Loh LL, So JBY, Shabbir A. Gallstone Disease After Laparoscopic Sleeve Gastrectomy in an Asian Population-What Proportion of Gallstones Actually Becomes Symptomatic? Obes Surg. 2017 Sep;27(9):2419-2423.
19. Abdallah E, Emile SH, Elfeki H, Fikry M, Abdelshafy M, Elshobaky A et al. Role of ursodeoxycholic acid in the prevention of gallstone formation after laparoscopic sleeve gastrectomy. Surg Today. 2017 Jul;47(7):844-850.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
