Screening for the Known Αlpha Thalassemia Deletions by Polymerase Chain Reaction

Year 2017, , 59 - 64, 01.10.2017

Kiran Tauseef Bukhari Nouman Noor Sadaf Humayoun Humaira Zafar Noor Khan Lakhnana

https://doi.org/10.5455/umj.20170608074047

Abstract

Thalassemia is the quantitatively inherited disorder of haemoglobin polypeptide chain synthesis. Awareness about the exact frequency of disease in our country, Pakistan, along with the appropriate knowledge of diagnostic and prevention approach will be a step forward to combat thalassemia in Pakistan. The proposed review article will provide updated information regarding the exact frequency and distribution of thalassemia in neonates in Pakistan and Internationally. All this ultimately provide a great help in establishing the policies for thalassemia prevention and control programs in Pakistan. Thalassemia is the quantitatively inherited disorder of hemoglobin polypeptide chain synthesis. Awareness about the exact frequency of disease in our country, Pakistan, along with the appropriate knowledge of diagnostic and prevention approach will be a step forward to combat thalassemia in Pakistan. The proposed review article will provide updated information regarding the exact frequency and distribution of thalassemia in neonates in Pakistan and Internationally. All this ultimately provide a great help in establishing the policies for thalassemia prevention and control programs in Pakistan.

Keywords

Alpha Thalassemia, Deletions, Polymerase chain reaction, Diagnosis, Prevention

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