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            <front>

                <journal-meta>
                                                                <journal-id>van vet j</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Van Veterinary Journal</journal-title>
            </journal-title-group>
                            <issn pub-type="ppub">2149-3359</issn>
                                        <issn pub-type="epub">2149-8644</issn>
                                                                                            <publisher>
                    <publisher-name>Van Yüzüncü Yıl Üniversitesi</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.36483/vanvetj.1020055</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Veterinary Surgery</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Veteriner Cerrahi</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <trans-title-group xml:lang="en">
                                    <trans-title>The Effect of Corynebacterium cutis Lysate on Immunoglobulin Levels in Smallpox Vaccinated Sheep Immunoglobulin Levels in Smallpox Vaccine Applications</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>Koyunlarda Çiçek Aşısı Uygulaması ile Birlikte Corynebacterium cutis Lizatının İmmunglobülin Düzeyleri Üzerine Etkisi</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-7878-574X</contrib-id>
                                                                <name>
                                    <surname>Yaşar</surname>
                                    <given-names>Ömer</given-names>
                                </name>
                                                                    <aff>Van Yüzüncü Yıl Üniversitesi Veteriner Fakültesi</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-4613-9334</contrib-id>
                                                                <name>
                                    <surname>Yüksek</surname>
                                    <given-names>Nazmi</given-names>
                                </name>
                                                                    <aff>VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20220728">
                    <day>07</day>
                    <month>28</month>
                    <year>2022</year>
                </pub-date>
                                        <volume>33</volume>
                                        <issue>2</issue>
                                        <fpage>46</fpage>
                                        <lpage>51</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20211106">
                        <day>11</day>
                        <month>06</month>
                        <year>2021</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20220424">
                        <day>04</day>
                        <month>24</month>
                        <year>2022</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1990, Van Veterinary Journal</copyright-statement>
                    <copyright-year>1990</copyright-year>
                    <copyright-holder>Van Veterinary Journal</copyright-holder>
                </permissions>
            
                                                                                                <trans-abstract xml:lang="en">
                            <p>In this study, the effect of apply Corynebacterium cutis lysate together with smallpox vaccine on immunoglobulin (IgG, IgM, IgA, IgE) levels in sheep was investigated. For this purpose, 20 mg Corynebacterium cutis lysate was administered to 10 sheep only with smallpox vaccine and 10 sheep with smallpox vaccine. Blood samples were obtained from V. jugularis for laboratory analysis from all animals on days 0, 21, and 35 of the study. Serum Ig, hematology and biochemical parameters were measured. Statistical differences were not determined in the sampling times of biochemical and hematological parameters, either within the group or between the groups. There was a significant increase in IgA levels between the 0th and 35th days in both groups (p</p></trans-abstract>
                                                                                                                                    <abstract><p>Bu çalışmada koyunlarda çiçek aşısı ile birlikte Corynebacterium cutis lizatının uygulanmasının immunglobulin (IgG, IgM, IgA, IgE) seviyeleri üzerine etkisi araştırıldı. Bu amaçla 10 koyuna sadece koyun çiçek aşısı ve 10 koyuna ise çiçek aşısı ile birlikte 20 mg Corynebacterium cutis lizatı yapıldı. Tüm hayvanlardan çalışmanın 0., 21. ve 35. günlerinde laboratuvar analizleri için V. jugularisten kan örnekleri alındı. Serum immunglobulin, hematoloji ve biyokimyasal parametreler ölçüldü. Biyokimyasal ve hematolojik parametrelerde örnekleme zamanlarında gerek grup içi gerekse gruplar arasında istatistikî farklılıklar belirlenmedi. IgA seviyelerinde her iki grupta 0. ile 35. günler arasında anlamlı artış (p</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>Koyun</kwd>
                                                    <kwd>  Çiçek aşısı</kwd>
                                                    <kwd>  Corynebacterium cutis</kwd>
                                                    <kwd>  immunstimulan</kwd>
                                                    <kwd>  immunglobülin</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="en">
                                                    <kwd>sheep</kwd>
                                                    <kwd>  pox vaccine</kwd>
                                                    <kwd>  corynebacteriu cutis</kwd>
                                                    <kwd>  immunstimulan</kwd>
                                                    <kwd>  immunoglobulin</kwd>
                                            </kwd-group>
                                                                                                                                    <funding-group specific-use="FundRef">
                    <award-group>
                                                    <funding-source>
                                <named-content content-type="funder_name">Van Yüzüncü Yıl Üniversitesi Bilimsel Araştırma Projeleri Koordinatörlüğü</named-content>
                            </funding-source>
                                                                            <award-id>TYL-2018-6983</award-id>
                                            </award-group>
                </funding-group>
                                </article-meta>
    </front>
    <back>
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