The effects of autologous platelet concentrate on the healing of intra-bony defects: a randomized clinical trial

Yıl 2019, Cilt: 53 Sayı: 1, 38 - 43, 31.01.2019

Nitin Kudyar Nitin Dani Shahab Saquib Abullais Nabeeh A. Alqahtani Aashima Gupta Nilofar Attar

Öz

Purpose

The present study aimed to evaluate the clinical and radiographic effects of

autologous platelet concentrate (APC) on the healing of intra-bony defects filled

with β-tricalcium phosphate (β-TCP) and covered with collagen membranes.

Subjects and methods

This study included 30 defects of 14 systemically healthy subjects. All of them had,

at least, two deep intra-bony, inter-proximal periodontal defects. Minimum probing

pocket depth (PPD) was 6 mm. Clinical and imaging examination was performed

both at baseline and at 3, 6, and 9 months after surgery.

Results

Both the test and control group revealed a significant reduction in all variables

when compared with the base line. Mean reduction of the PPD in two groups at

each follow-up time point showed no significant difference. Means of the clinical

attachment gain of the same groups were significantly different (p<0.05). Mean

gingival recession at 3 month was not significant. However, the means of gingival

recession coverage of two groups were significantly different at 6 and 9 months

(p<0.05 for both).

Conclusion

Sites treated with APC are more likely to demonstrate more clinical attachment gain

and recession coverage at the end of 9 month compared to those without APC.

Anahtar Kelimeler

Intra-bony defects, periodontal regeneration, periodontitis, latelet rich plasma, β‑tricalcium phosphate

Kaynakça

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