Year 2019, Volume 8, Issue 1, Pages 98 - 105 2019-01-01

INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE

Halil İbrahim GÜLER [1]

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The most important characteristic of coronary artery disease, which is one of the most common and most important health problems today, is that it can lead to life-threatening myocardial infarction in advanced stages. It is more important to take protective preventions by knowing the risk factors that cause the disease rather than the treatment of this disease. This study was performed on coronary artery disease (CAD) to determine the frequency of the interleukin-6 gene (IL-6) 572G/C polymorphism and to examine the role of this polymorphism in CAD development. Genomic DNA obtained from 185 persons (103 CAD patients, 82 controls) was used in the study. IL-6 572 G/C polymorphism genotypes were determined using PCR, RFLP and electrophoresis. The results were statistically analyzed. The frequencies of 572 G/C genotypes, in controls GG 83%, GC 17%, CC 0% and in CAD patients GG 72% , GC 28% and CC 0% were found. There was no significant difference between the control group and the patient groups in genotype frequencies. It was determined that GG genotype frequency increases significantly in patients according to control group. Based on the results of our study, we may suggest that there is no association between CAD and IL-6 572G / C polymorphism.
Coronary Artery Disease, CAD, IL-6 polymorphism, rs1800796
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Journal Section Articles
Authors

Author: Halil İbrahim GÜLER

Dates

Publication Date: January 1, 2019

Bibtex @ { estubtdc525544, journal = {Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji}, issn = {2667-4203}, address = {Eskişehir Teknik Üniversitesi}, year = {2019}, volume = {8}, pages = {98 - 105}, doi = {}, title = {INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE}, key = {cite}, author = {GÜLER, Halil İbrahim} }
APA GÜLER, H . (2019). INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE. Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji, 8 (1), 98-105. Retrieved from http://dergipark.org.tr/estubtdc/issue/43264/525544
MLA GÜLER, H . "INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE". Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji 8 (2019): 98-105 <http://dergipark.org.tr/estubtdc/issue/43264/525544>
Chicago GÜLER, H . "INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE". Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji 8 (2019): 98-105
RIS TY - JOUR T1 - INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE AU - Halil İbrahim GÜLER Y1 - 2019 PY - 2019 N1 - DO - T2 - Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji JF - Journal JO - JOR SP - 98 EP - 105 VL - 8 IS - 1 SN - 2667-4203- M3 - UR - Y2 - 2019 ER -
EndNote %0 Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE %A Halil İbrahim GÜLER %T INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE %D 2019 %J Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji %P 2667-4203- %V 8 %N 1 %R %U
ISNAD GÜLER, Halil İbrahim . "INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE". Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji 8 / 1 (January 2019): 98-105.
AMA GÜLER H . INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE. Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji. 2019; 8(1): 98-105.
Vancouver GÜLER H . INVESTIGATION OF RELATIONSHIP BETWEEN rs1800796 VARIANTS OF INTERLEUKINE-6 GENE AND CORONARY ARTERY DISEASE. Eskişehir Teknik Üniversitesi Bilim ve Teknoloji Dergisi - C Yaşam Bilimleri Ve Biyoteknoloji. 2019; 8(1): 105-98.