Year 2016, Volume 2, Issue 3, Pages 188 - 194 2016-09-06

Comparison of bupivacaine and levobupivacaine for treatment of post-thoracotomy pain through thoracic paravertebral block

Sener Kaya [1] , Elif Basagan Mogol [2] , Fatma Nur Kaya [3] , Ahmet Sami Bayram [4] , Gurkan Turker [5] , Canan Yilmaz [6] , Derya Karasu [7]

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Objectives. The aim of this study was to compare postoperative pain and respiratory functions of lobectomy patients who were given bupivacaine or levobupivacaine with fentanyl through a paravertebral catheter. Methods. ASA I-II patients (n=40, 18-65 years old) randomized into two groups. While Group B was administered 0.25% bupivacaine with fentanyl, Group L was administered 0.25% levobupivacaine with fentanyl at a rate of 0.1 ml/kg/hr through paravertebral catheter for patient controlled analgesia. Visual analog scale (VAS), arterial blood gases and respiratory function tests were assessed. Results. There were no significant differences in terms of demographic characteristics and surgery durations between the groups (p>0.05). VAS scores recorded at the 1st postoperative hour were higher in both groups compared to the following hours (p<0.001), but there was no difference between the groups. FEV1 and FVC measured in the postoperative period were significantly lower than preoperative values in both groups (p<0.001); however, there was no significant difference between the groups. There was no significant difference between the two groups regarding side effects, mean values of PaO2, PaCO2 and SpO2 (p>0.05). Conclusion. Bupivacaine and levobupivacaine had equivalent efficiency and could be safely used in treatment of post-thoracotomy pain through thoracic paravertebral block.

Bupivacaine, levobupivacaine hydrochloride; post-thoracotomy pain; thoracic paravertebral block
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Journal Section Original Articles
Authors

Author: Sener Kaya
Institution: Department of Anesthesiology and Reanimation, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Country: Turkey


Author: Elif Basagan Mogol
Institution: Department of Anesthesiology and Reanimation, Uludag University School of Medicine, Bursa
Country: Turkey


Author: Fatma Nur Kaya
Institution: Department of Anesthesiology and Reanimation, Uludag University School of Medicine, Bursa
Country: Turkey


Author: Ahmet Sami Bayram
Institution: Department of Thoracic Surgery, Uludag University School of Medicine, Bursa
Country: Turkey


Author: Gurkan Turker
Institution: Department of Anesthesiology and Reanimation, Uludag University School of Medicine, Bursa
Country: Turkey


Author: Canan Yilmaz
Institution: Department of Anesthesiology and Reanimation, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Country: Turkey


Author: Derya Karasu
Institution: Department of Anesthesiology and Reanimation, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa
Country: Turkey


EndNote %0 The European Research Journal Comparison of bupivacaine and levobupivacaine for treatment of post-thoracotomy pain through thoracic paravertebral block %A Sener Kaya , Elif Basagan Mogol , Fatma Nur Kaya , Ahmet Sami Bayram , Gurkan Turker , Canan Yilmaz , Derya Karasu %T Comparison of bupivacaine and levobupivacaine for treatment of post-thoracotomy pain through thoracic paravertebral block %D 2016 %J The European Research Journal %P -2149-3189 %V 2 %N 3 %R doi: 10.18621/eurj.2016.5000188659 %U 10.18621/eurj.2016.5000188659