Evaluation of hearing results in Behçet's disease

Yıl 2019, Cilt: 5 Sayı: 3, 535 - 539, 04.05.2019

Cem Bayraktar Özlem Yağız Aghayarov Sedat Doğan Demet Işık Bayraktar Ahmet Altuntaş

https://doi.org/10.18621/eurj.379685

Cited By: 1

Öz

Objectives: Behçet's disease is an inflammatory rheumatic disease
with recurrent scarring in the oral and genital area, as well as skin, eye,
joint, vein, and nerve involvement. The aim of the study was to investigate the
level of hearing in Behçet’s disease and whether there is a change in hearing
levels as the level of the disease increases.

Methods: In this study we
examined 32 patients with Behçet’s disease and 50 healthy volunteers. All
patients were evaluated with audiometry, tympanometry and acoustic reflex
tests, as well as detailed ear, nose, and throat examinations.

Results:
Sensorineural hearing loss was observed in 9.3% of the patients with Behçet's disease,
according to the audiological data, and all patients were bilateral. We also observed
sensorineural hearing loss to be the fifth most common symptom in our study.
Especially in high frequencies, there was positive correlation between hearing
levels and disease exposure time (p
< 0.05).

Conclusions: We think that the audiological examinations should
be included in the routine check-ups of Behçet's patients. In addition, a
follow-up assessment of the hearing level of these patients with high frequency
audiometry may be more meaningful. 

Anahtar Kelimeler

Behçet disease, hearing loss, audiometry

Kaynakça

• [1] Marshall SE. Behçet’s disease. Best Pract Res Clin Rheumatol 2004;18:291-311.
• [2] Soylu M, Ersoz TR, Erken E. The association between HLA B5 and ocular involvement in Behçet’s disease in southern Turkey. Acta Ophthalmol (Copenh) 1992;70:786-9.
• [3] Dagli M, Eryilmaz A, Tanrikulu S, Aydın A, Gonul M, Gul U, et al. Evaluation of cochlear involvement by distortion product otoacoustic emission in Behçet’s disease. Auris Nasus Larynx 2008;35:333-7.
• [4] Zeidan MJ, Saadoun D, Garrido M, Klatzmann D, Six A, Cacoub P. Behçet’s disease physiopathology: a contemporary review. Auto Immun Highlights 2016;7:4.
• [5] Sarr SA, Fall PD, Mboup MC, Dia K, Bodian M, Jobe M. Superior vena cava syndrome revealing a Behçet’s disease. Thromb J 2015;13:7.
• [6] Lai C, Sun Y, Wang J, Purvin VA, He Y, Yang Q, et al. Optic perineuritis in Behçet disease. J Neuroophthalmol 2015;35:342-7.
• [7] Morgan ML, EspinoBarros Palau A, Lee AG, Foroozan R. Neuro-Behçet disease presenting with oculopalatal tremor. J Neuroophthalmol 2015;35:51-3.
• [8] White AS, Taylor RL, McNeill C, Garsia R, Welgampola MS. Behçet’s disease presenting as a peripheralvestibulopathy. J ClinNeurosci 2014;21:1060-3.
• [9] Alajouanine T, Castaigne V, Lhermitte F, Gambier J, Gautier JC. La meningo-encephalite de la maladie de Behçet. Presse Med 1961;69:2579-82.
• [10] Elidan J, Levi H, Cohen E, BenEzra D. Effect of cyclosporine A on the hearing loss in Behçet’s disease. Ann Otol Rhinol Laryngol 1991;100:464-8.
• [11] International Study Group for Behçet’s Disease. Evaluation of diagnostic (classification) criteria in Behçet’s disease-to wards internationally agreed criteria. Br J Rheumatol 1992;31:299-308.
• [12] Yazici H, Yurdakul S, Hamuryudan V. Behçet’ssyndrome. In: Mad- dison PJ, Isenberg DA, Woo P, Glass DN, editors. Oxford textbook of rheumatology. 2nd ed. Oxford: Oxford Medical Publications; 1998:pp.1394-403.
• [13] Chajek T, Fainaru M. Behçet’sdisease. Report of 41 cases and review of the literature. Medicine 1975;54:179-95.
• [14] Nadeau SE, Watson RT. Neurologic manifestations of vasculitis and collagen vascular syndromes. In: Joynt RJ, editor. Clinical neurology. Philadelphia: JB Lippincott. 1992:pp.1-166.
• [15] Ehrlich GE. Vasculitis in Behçet’s disease. Int Rev Immunol 1997;14:81-8.
• [16] Hirohata S, Kikuchi H. Behçet’s disease. Arthritis Res Ther 2003;5:139-46.
• [17] Onder M, Gürer MA. The multiple faces of Behçet’s disease and its aetiological factors. J Eur Acad Dermatol Venereol 2001;15:126-36.
• [18] Berrettini S, Bruschini P, Sellari Franceschini S, Mita L, Olivieri I, Gemignani G. [Sudden deafness and Behçet’s disease]. Acta Otorhinolaryngol Belg 1989;43:221-9. [Article in French].
• [19] Hagiwara N, Harashima S, Tukamoto H, Horiuchi T. [A case of Behçet’s disease with chronic and repeated sudden hearing loss: successful treatment with intravenous cyclophosphamide pulse therapy]. Ryumachi 2001;41:858-63. 
[Article in Japanese]
• [20] Arts HA. Sensorineural hearing loss: evaluation and management in adults. In: Cummings CW, Flint PW, Harker LA, Haughey BH, Richardson MA, Robbins KT, et al., eds. Cummings Otolaryngology-Head and NeckSurgery, 4th ed. Philadelphia: Mosby. 2005:pp.3535-61.
• [21] Belkahia A, Ben Ayed H, Ben H’Mida M, Hamza M. [Auditory and vestibular lesions in Behcet's disease]. Ann Otolaryngol Chir Cervicofac 1982;99:469-76. 
[Article in French]
• [22] Andreoli C, Savastano M. Audiologicpathology in Behçet’s syndrome. Ann J Otol 1989;10:466-67.
• [23] Gemignani G, Berrettini S, Bruschini P, Sellari-Franceschini S, Fusari P, Piragine F, et al. Hearing and vestibular disturbances in Behçet’s syndrome. Ann Otol Rhinol Laryngol 1991;100:459-63.
• [24] Bayazit YA, Yilmaz M, Gunduz B, Altinyay S, Kemaloglu YK, Onder M, et al. Distortion product otoacoustice mission findings in Behcet’s disease and rheumatoid arthritis. ORL J Otorhinolaryngol Relat Spec 2007;69:233-8.
• [25] Ak E, Harputluoglu U, Oghan F, Baykal B. Behcet’s disease and hearing loss. Auris Nasus Larynx 2004;31:29-33.
• [26] Soylu L, Aydogan B, Soylu M, Ozsahinoglu C. Hearing loss in Behçet’sdisease. Ann Otol Rhinol Laryngol 1995;104:864-7.
• [27] Aslan S, Serarslan G, Savas N, Teksoz E, Dagli S. Hearing loss in patients with Behçet’s disease: an audiological and transient evoked otoacoustice mission study. J Laryngol Otol 2010;124:10-5.
• [28] Miura MS, LubiancaNeto JF, Krumenauer RC, Prates K, de Castro R, Saffer M. Behçet’s disease: external ear involvement. Int J Pediatr Otorhinolaryngol 2004;68: 817-21.
• [29] Bakhshaee M, Ghasemi MM, Hatef MR, Talebmehr M, Shakeri MT. Hearing loss in Behçet syndrome. Otolaryngol Head Neck Surg 2007;137:439-42.
• [30] Sonbay ND, Saka C, Tatlican S, Vuralkan E, Aygener N, Eren C, et al. Audiological evaluation in patients with Behçet’s disease. J Laryngol Otol 2014;128:694-7.
• [31] Evereklioglu C, Cokkeser Y, Doganay S, Er H, Kizilay A. Audio-vestibular evaluation in patients with Behçet’s syndrome. J Laryngol Otol 2001;115:704-8.
• [32] Brama I, Fainaru M. Inner ear involvement in Behçet’s disease. Arch Otolaryngol 1980;106:215-7.
• [33] Sota J, Vitale A, Orlando I, Lopalco G, Franceschini R, Fabiani C, et al. Auditory involvement in Behcet's disease: relationship with demographic, clinical, and therapeutic characteristics. Clin Rheumatol 2017;36:445-9.
• [34] Kulahli I, Balci K, Koseoglu E, Yuce I, Cagli S, Senturk M. Audio-vestibular disturbances in Behcet’s patients: report of 62 cases. Hear Res 2005;203:28-31.
• [35] Erbek S, Erbek SS, Yilmaz S, Yucel E, Ozluoglu LN. Vestibular evoked myogenic potentials in Behcet’sdisease. Eur Arch Otorhinolaryngol 2008;265:1315-20.