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TREATMENT OF MALIGNANT EPITHELIAL HAIR FOLLICLE TUMORS

Yıl 2018, Cilt: 3 Sayı: 3, 92 - 95, 28.03.2018

Öz

Trichilemmal carcinoma and malignant proliferating trichilemmal tumor are very rare tumors that can be local or very aggressive with sistemic metastases originating from outher root sheat epithelium of the hair follicles. These tumors can be misdiagnosed with other skin cancers clinically. Wide surgical excision is the standart treatment in local disease. Recurrence may be seen. There is still no standart adjuvant therapy for sistemic disease of both tumors. Scan of the patients for staging and close follow-up are mandatory for prognose of the diseases.

Kaynakça

  • 1. Headington JT. Tumors of the hair follicle. A review. The American journal of pathology 1976;85(2):479-514.2. Garrett AB, Azmi FH, Ogburia KS. Trichilemmal carcinoma: a rare cutaneous malignancy: a report of two cases. Dermatol Surg 2004;30(1):113-5.3. Takata M, Rehman I, Rees JL. A trichilemmal carcinoma arising from a proliferating trichilemmal cyst: the loss of the wild-type p53 is a critical event in malignant transformation. Hum Pathol 1998;29(2):193-5. [published Online First: 1998/03/07]4. Deshmukh BD, Kulkarni MP, Momin YA, et al. Malignant proliferating trichilemmal tumor: a case report and review of literature. J Cancer Res Ther 2014;10(3):767-9. doi: 10.4103/0973-1482.1360365. Cotton D. Troublesome tumours. 1: Adnexal tumours of the skin. J Clin Pathol 1991;44(7):543-8.6. Stam H, Lohuis PJ, Zupan-Kajcovski B, et al. Increasing incidence and survival of a rare skin cancer in the Netherlands. A population-based study of 2,220 cases of skin adnexal carcinoma. J Surg Oncol 2013;107(8):822-7. doi: 10.1002/jso.23331 [published Online First: 2013/03/19]7. Hamman MS, Brian Jiang SI. Management of Trichilemmal Carcinoma: An Update and Comprehensive Review of the Literature. Dermatol Surg 2014 doi: 10.1111/DSU.00000000000000028. Reis JP, Tellechea O, Cunha MF, et al. Trichilemmal carcinoma: review of 8 cases. J Cutan Pathol 1993;20(1):44-9.9. Ko T, Tada H, Hatoko M, et al. Trichilemmal carcinoma developing in a burn scar: a report of two cases. J Dermatol 1996;23(7):463-8.10. Satyaprakash AK, Sheehan DJ, Sangueza OP. Proliferating trichilemmal tumors: a review of the literature. Dermatol Surg 2007;33(9):1102-8. doi: 10.1111/j.1524-4725.2007.33225.x11. Evrenos MK, Bali ZU, Temiz P, et al. Malignant Proliferating Trichilemmal Tumor: Clinical Presentations, Treatment, and Outcomes. Turkish Journal of Plastic Surgery 2018;26:24+.12. Dubhashi SP, Jadhav SK, Parasnis A, et al. Recurrent malignant proliferating trichilemmal tumor with lymph node metastasis in a young woman. J Postgrad Med 2014;60(4):400-2. doi: 10.4103/0022-3859.14397313. Park BS, Yang SG, Cho KH. Malignant proliferating trichilemmal tumor showing distant metastases. Am J Dermatopathol 1997;19(5):536-9.14. Allee JE, Cotsarelis G, Solky B, et al. Multiply recurrent trichilemmal carcinoma with perineural invasion and cytokeratin 17 positivity. Dermatol Surg 2003;29(8):886-9.15. Kulahci Y, Oksuz S, Kucukodaci Z, et al. Multiple recurrence of trichilemmal carcinoma of the scalp in a young adult. Dermatol Surg 2010;36(4):551-4. doi: 10.1111/j.1524-4725.2010.01498.x16. Yi HS, Sym SJ, Park J, et al. Recurrent and metastatic trichilemmal carcinoma of the skin over the thigh: a case report. Cancer Res Treat 2010;42(3):176-9. doi: 10.4143/crt.2010.42.3.17617. Tikku G, Jain D, Grover R. Malignant proliferating trichilemmal tumor of the scalp masquerading as squamous cell carcinoma: a need for common awareness. Indian J Pathol Microbiol 2014;57(4):646-7. doi: 10.4103/0377-4929.14270518. Evrenos MK, Kerem H, Temiz P, et al. Malignant tumor of outer root sheath epithelium, trichilemmal carcinoma. Clinical presentations, treatments and outcomes. Saudi Med J 2018;39(2):213-16. doi: 10.15537/smj.2018.2.21085 [published Online First: 2018/02/14]19. Ye J, Nappi O, Swanson PE, et al. Proliferating pilar tumors: a clinicopathologic study of 76 cases with a proposal for definition of benign and malignant variants. Am J Clin Pathol 2004;122(4):566-74. doi: 10.1309/21DK-LY2R-94H1-92NK20. Tolkachjov SN, Hocker TL, Camilleri MJ, et al. Mohs micrographic surgery in the treatment of trichilemmal carcinoma: the Mayo Clinic experience. J Am Acad Dermatol 2015;72(1):195-6. doi: 10.1016/j.jaad.2014.10.00721. Behroozan DS, Goldberg LH, Glaich AS, et al. Mohs micrographic surgery for deeply penetrating, expanding benign cutaneous neoplasms. Dermatol Surg 2006;32(7):958-65. doi: 10.1111/j.1524-4725.2006.32204.x22. Fieleke DR, Goldstein GD. Malignant proliferating trichilemmal tumor treated with Mohs surgery: proposed protocol for diagnostic work-up and treatment. Dermatol Surg 2015;41(2):292-4. doi: 10.1097/DSS.000000000000026923. Siddha M, Budrukkar A, Shet T, et al. Malignant pilar tumor of the scalp: a case report and review of literature. J Cancer Res Ther 2007;3(4):240-3.24. Sharma R, Verma P, Yadav P, et al. Proliferating trichilemmal tumor of scalp: benign or malignant, a dilemma. J Cutan Aesthet Surg 2012;5(3):213-5. doi: 10.4103/0974-2077.10139425. Amato M, Esmaeli B, Ahmadi MA, et al. Feasibility of preoperative lymphoscintigraphy for identification of sentinel lymph nodes in patients with conjunctival and periocular skin malignancies. Ophthalmic Plast Reconstr Surg 2003;19(2):102-6. doi: 10.1097/01.IOP.0000056146.62409.24 [published Online First: 2003/03/20]26. Nijhawan N, Ross MI, Diba R, et al. Experience with sentinel lymph node biopsy for eyelid and conjunctival malignancies at a cancer center. Ophthalmic Plast Reconstr Surg 2004;20(4):291-5. [published Online First: 2004/07/22]

MALİGN EPİTELYAL KIL FOLİKÜLÜ TÜMÖRLERİNDE TEDAVİ

Yıl 2018, Cilt: 3 Sayı: 3, 92 - 95, 28.03.2018

Öz

Trikilemmal karsinom ve malign proliferatif trikilemmal tümör; kıl folikülü dış kök epiteli kaynaklı, oldukça nadir görülen ve lokal ya da sistemik metastaz yaparak agresif seyirli olabilen malign tümörlerdir. Klinik olarak diğer deri kanserleri ile karışabilir. Lokal hastalıkta tedavisi geniş cerrahi eksizyondur. Tekrarlayan nüksler görülebilir. Sistemik hastalıkta önerilen adjuvan tedavi bulunmamaktadır. Tanı alan hastalarda görüntüleme ile evreleme ve cerrahi sonrasında yakın takip hastalık prognozu açısından önemlidir.

Kaynakça

  • 1. Headington JT. Tumors of the hair follicle. A review. The American journal of pathology 1976;85(2):479-514.2. Garrett AB, Azmi FH, Ogburia KS. Trichilemmal carcinoma: a rare cutaneous malignancy: a report of two cases. Dermatol Surg 2004;30(1):113-5.3. Takata M, Rehman I, Rees JL. A trichilemmal carcinoma arising from a proliferating trichilemmal cyst: the loss of the wild-type p53 is a critical event in malignant transformation. Hum Pathol 1998;29(2):193-5. [published Online First: 1998/03/07]4. Deshmukh BD, Kulkarni MP, Momin YA, et al. Malignant proliferating trichilemmal tumor: a case report and review of literature. J Cancer Res Ther 2014;10(3):767-9. doi: 10.4103/0973-1482.1360365. Cotton D. Troublesome tumours. 1: Adnexal tumours of the skin. J Clin Pathol 1991;44(7):543-8.6. Stam H, Lohuis PJ, Zupan-Kajcovski B, et al. Increasing incidence and survival of a rare skin cancer in the Netherlands. A population-based study of 2,220 cases of skin adnexal carcinoma. J Surg Oncol 2013;107(8):822-7. doi: 10.1002/jso.23331 [published Online First: 2013/03/19]7. Hamman MS, Brian Jiang SI. Management of Trichilemmal Carcinoma: An Update and Comprehensive Review of the Literature. Dermatol Surg 2014 doi: 10.1111/DSU.00000000000000028. Reis JP, Tellechea O, Cunha MF, et al. Trichilemmal carcinoma: review of 8 cases. J Cutan Pathol 1993;20(1):44-9.9. Ko T, Tada H, Hatoko M, et al. Trichilemmal carcinoma developing in a burn scar: a report of two cases. J Dermatol 1996;23(7):463-8.10. Satyaprakash AK, Sheehan DJ, Sangueza OP. Proliferating trichilemmal tumors: a review of the literature. Dermatol Surg 2007;33(9):1102-8. doi: 10.1111/j.1524-4725.2007.33225.x11. Evrenos MK, Bali ZU, Temiz P, et al. Malignant Proliferating Trichilemmal Tumor: Clinical Presentations, Treatment, and Outcomes. Turkish Journal of Plastic Surgery 2018;26:24+.12. Dubhashi SP, Jadhav SK, Parasnis A, et al. Recurrent malignant proliferating trichilemmal tumor with lymph node metastasis in a young woman. J Postgrad Med 2014;60(4):400-2. doi: 10.4103/0022-3859.14397313. Park BS, Yang SG, Cho KH. Malignant proliferating trichilemmal tumor showing distant metastases. Am J Dermatopathol 1997;19(5):536-9.14. Allee JE, Cotsarelis G, Solky B, et al. Multiply recurrent trichilemmal carcinoma with perineural invasion and cytokeratin 17 positivity. Dermatol Surg 2003;29(8):886-9.15. Kulahci Y, Oksuz S, Kucukodaci Z, et al. Multiple recurrence of trichilemmal carcinoma of the scalp in a young adult. Dermatol Surg 2010;36(4):551-4. doi: 10.1111/j.1524-4725.2010.01498.x16. Yi HS, Sym SJ, Park J, et al. Recurrent and metastatic trichilemmal carcinoma of the skin over the thigh: a case report. Cancer Res Treat 2010;42(3):176-9. doi: 10.4143/crt.2010.42.3.17617. Tikku G, Jain D, Grover R. Malignant proliferating trichilemmal tumor of the scalp masquerading as squamous cell carcinoma: a need for common awareness. Indian J Pathol Microbiol 2014;57(4):646-7. doi: 10.4103/0377-4929.14270518. Evrenos MK, Kerem H, Temiz P, et al. Malignant tumor of outer root sheath epithelium, trichilemmal carcinoma. Clinical presentations, treatments and outcomes. Saudi Med J 2018;39(2):213-16. doi: 10.15537/smj.2018.2.21085 [published Online First: 2018/02/14]19. Ye J, Nappi O, Swanson PE, et al. Proliferating pilar tumors: a clinicopathologic study of 76 cases with a proposal for definition of benign and malignant variants. Am J Clin Pathol 2004;122(4):566-74. doi: 10.1309/21DK-LY2R-94H1-92NK20. Tolkachjov SN, Hocker TL, Camilleri MJ, et al. Mohs micrographic surgery in the treatment of trichilemmal carcinoma: the Mayo Clinic experience. J Am Acad Dermatol 2015;72(1):195-6. doi: 10.1016/j.jaad.2014.10.00721. Behroozan DS, Goldberg LH, Glaich AS, et al. Mohs micrographic surgery for deeply penetrating, expanding benign cutaneous neoplasms. Dermatol Surg 2006;32(7):958-65. doi: 10.1111/j.1524-4725.2006.32204.x22. Fieleke DR, Goldstein GD. Malignant proliferating trichilemmal tumor treated with Mohs surgery: proposed protocol for diagnostic work-up and treatment. Dermatol Surg 2015;41(2):292-4. doi: 10.1097/DSS.000000000000026923. Siddha M, Budrukkar A, Shet T, et al. Malignant pilar tumor of the scalp: a case report and review of literature. J Cancer Res Ther 2007;3(4):240-3.24. Sharma R, Verma P, Yadav P, et al. Proliferating trichilemmal tumor of scalp: benign or malignant, a dilemma. J Cutan Aesthet Surg 2012;5(3):213-5. doi: 10.4103/0974-2077.10139425. Amato M, Esmaeli B, Ahmadi MA, et al. Feasibility of preoperative lymphoscintigraphy for identification of sentinel lymph nodes in patients with conjunctival and periocular skin malignancies. Ophthalmic Plast Reconstr Surg 2003;19(2):102-6. doi: 10.1097/01.IOP.0000056146.62409.24 [published Online First: 2003/03/20]26. Nijhawan N, Ross MI, Diba R, et al. Experience with sentinel lymph node biopsy for eyelid and conjunctival malignancies at a cancer center. Ophthalmic Plast Reconstr Surg 2004;20(4):291-5. [published Online First: 2004/07/22]
Toplam 1 adet kaynakça vardır.

Ayrıntılar

Birincil Dil Türkçe
Konular Sağlık Kurumları Yönetimi
Bölüm Kısa Derlemeler
Yazarlar

Mustafa Evrenos

Yayımlanma Tarihi 28 Mart 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 3 Sayı: 3

Kaynak Göster

APA Evrenos, M. (2018). MALİGN EPİTELYAL KIL FOLİKÜLÜ TÜMÖRLERİNDE TEDAVİ. Güncel Dermatoloji Dergisi, 3(3), 92-95.
AMA Evrenos M. MALİGN EPİTELYAL KIL FOLİKÜLÜ TÜMÖRLERİNDE TEDAVİ. GDD. Mart 2018;3(3):92-95.
Chicago Evrenos, Mustafa. “MALİGN EPİTELYAL KIL FOLİKÜLÜ TÜMÖRLERİNDE TEDAVİ”. Güncel Dermatoloji Dergisi 3, sy. 3 (Mart 2018): 92-95.
EndNote Evrenos M (01 Mart 2018) MALİGN EPİTELYAL KIL FOLİKÜLÜ TÜMÖRLERİNDE TEDAVİ. Güncel Dermatoloji Dergisi 3 3 92–95.
IEEE M. Evrenos, “MALİGN EPİTELYAL KIL FOLİKÜLÜ TÜMÖRLERİNDE TEDAVİ”, GDD, c. 3, sy. 3, ss. 92–95, 2018.
ISNAD Evrenos, Mustafa. “MALİGN EPİTELYAL KIL FOLİKÜLÜ TÜMÖRLERİNDE TEDAVİ”. Güncel Dermatoloji Dergisi 3/3 (Mart 2018), 92-95.
JAMA Evrenos M. MALİGN EPİTELYAL KIL FOLİKÜLÜ TÜMÖRLERİNDE TEDAVİ. GDD. 2018;3:92–95.
MLA Evrenos, Mustafa. “MALİGN EPİTELYAL KIL FOLİKÜLÜ TÜMÖRLERİNDE TEDAVİ”. Güncel Dermatoloji Dergisi, c. 3, sy. 3, 2018, ss. 92-95.
Vancouver Evrenos M. MALİGN EPİTELYAL KIL FOLİKÜLÜ TÜMÖRLERİNDE TEDAVİ. GDD. 2018;3(3):92-5.