Adenotonsillektomi ve Adenoidektominin Mean Platelet Volüm (MPV) düzeyleri üzerine etkisi

Yıl 2016, Cilt: 6 Sayı: 2, 76 - 80, 19.10.2016

Serhan Derin Murat Şahan Hatice Topal Yaşar Topal

https://doi.org/10.16899/ctd.77472

Öz

Amaç: Adenotonsiller hipertrofiler (ATH) kardiyopulmoner hastalıklar başta olmak üzere bir çok hastalığa neden olmaktadır. Daha önceki çalışmalar ATH li hastalarda pulmoner arter hipertansiyon insidansının arttığını ve adenotonsillektomi ile gerilediğini raporlamışlardır. Mean platelet volüm (MPV) son çalışmalarda bir çok kardiyak hastalıkta olduğu gibi pulmoner hipertansiyonda da prognostik kriter olma yolundadır. Büyük trombositler daha fazla proinflamatuar, protrombotik ve vazomotor aktiviteye sahiptir. Bu çalışmanın amacı adenotonsillektomi ve adenoidektomi operasyonu sonrası MPV değişimleri olup olmadığını  araştırmaktır. 

Hastalar ve Metod: Bu çalışmada ATH de MPV değerleri ölçüldü ve cerrahi tedavilerin MPV değerleri üserine etkisi araştırıldı. Otuz beş hastaya adenotonsillektomi, 30 hastaya adenoidektomi yapıldı. Preoperatif ve postoperatif 3. ay hemogram sonuçları karşılaştırıldı.  

Bulgular: Hastaların ortalama yaşı 6.51 ± 2.75 (2-16)’tı. Operasyon sonrası MPV değerlerindeki düşüş istatistiksel olarak anlamlıydı. (Preoperatif 9,75±0,95; Postoperatif 8,14±1,25). p<0,005

Sonuç: Adenotonsillektomi ve adenoidektomi operasyonları kardiyopulmoner komplikasyon belirteci olan MPV değerlerini etkili şekilde düşürmektedir. 

Anahtar Kelimeler

Mean platelet volüm(MPV), Adenotonsiller hipertrofi, Adenotonsillektomi, Adenoidektomi.

Impact of Adenotonsillectomy and Adenoidectomy on Mean Platelet Volume (MPV) Levels

Öz

-Adenotonsillar hypertrophy (ATH) leads to many disorders, especially cardiopulmonary diseases. Previous studies have reported the increase in pulmonary hypertension incidence in patients with ATH, as well as a decrease after adenotonsillectomy. Mean platelet volume (MPV) is becoming a prognostic indicator for pulmonary hypertension in recent studies, as it is in most cardiac diseases. It is known that larger platelets have increased proinflammatory and vasomotor activity, and prothrombotic potential. The purpose of this study to investigate whether of MPV levels changes after adenotonsillectomy and adenoidectomy.Methods- In this study, MPV values in patients with ATH were evaluated, and the impact of surgical treatment on MPV levels was analyzed. Thirty-five patients had adenotonsillectomy, while the remaining 30 patients had adenoidectomy. The preoperative and postoperative third month hemogram results were compared. Results- The mean age of the children was 6.51 ± 2.75 (2-16) years. The decrease in MPV levels after the operation was statistically significant (Preoperative 9,75±0,95

Anahtar Kelimeler

Mean platelet volume (MPV); Adenotonsillar hypertrophy; Adenotonsillectomy; Adenoidectomy.

Kaynakça

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