Year 2017, Volume 1, Issue 1, Pages 16 - 27 2017-04-30

Biology of procalcitonin and its potential role in veterinary medicine

Erdal Matur [1] , Evren Eraslan [2] , Ülker Çötelioğlu [3]

213 511

Procalcitonin is the precursor of calcitonin hormone, produced by C cells of thyroid gland in physiological conditions. It is also produced in parenchymal cells of many tissues and leukocytes in pathological situations. In the normal condition, procalcitonin is converted by specific enzymes to the calcitonin. Therefore, it is amount in circulation is very low. On the contrary, it increases in the blood and tissue during diseases, because the procalcitonin produced in parenchymal cells cannot be converted to calcitonin. A great number of data has been documented about procalcitonin in human at the physiological and pathological conditions. Furthermore, productions, genetic regulation, kinetics, analysis methods, it is relation with cytokines and diseases have been studied extensively. Consequently, it is used as a reliable biomarker in human medicine, particularly for widespread bacterial infections. However, little is known about the implications in veterinary medicine. In terms of lightening the veterinary field, basic information and new findings on procalcitonin has been reviewed once more, although, quite a few studies have been conducted on procalcitonin in domestic or farm animals. The findings show that production and kinetics of procalcitonin in animals may be quite different, in both of the normal or pathologic conditions. It is not yet used as a biomarker in veterinary medicine. In addition, it has not yet been investigated whether it has an effect on reducing the antibiotics usage in animals.

 

procalcitonin, horse, dog, animal, veterinary
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Primary Language en
Subjects Veterinary
Journal Section Review Articles
Authors

Author: Erdal Matur
Country: Turkey


Author: Evren Eraslan
Country: Turkey


Author: Ülker Çötelioğlu
Country: Turkey


Bibtex @review { http-www-jivs-net311279, journal = {Journal of Istanbul Veterinary Sciences}, issn = {2602-3490}, eissn = {2602-3490}, address = {The Chamber of Veterinary Surgeons, Istanbul}, year = {2017}, volume = {1}, pages = {16 - 27}, doi = {10.30704/http-www-jivs-net.311279}, title = {Biology of procalcitonin and its potential role in veterinary medicine}, key = {cite}, author = {Matur, Erdal and Eraslan, Evren and Çötelioğlu, Ülker} }
APA Matur, E , Eraslan, E , Çötelioğlu, Ü . (2017). Biology of procalcitonin and its potential role in veterinary medicine. Journal of Istanbul Veterinary Sciences, 1 (1), 16-27. DOI: 10.30704/http-www-jivs-net.311279
MLA Matur, E , Eraslan, E , Çötelioğlu, Ü . "Biology of procalcitonin and its potential role in veterinary medicine". Journal of Istanbul Veterinary Sciences 1 (2017): 16-27 <http://dergipark.org.tr/http-www-jivs-net/issue/28645/311279>
Chicago Matur, E , Eraslan, E , Çötelioğlu, Ü . "Biology of procalcitonin and its potential role in veterinary medicine". Journal of Istanbul Veterinary Sciences 1 (2017): 16-27
RIS TY - JOUR T1 - Biology of procalcitonin and its potential role in veterinary medicine AU - Erdal Matur , Evren Eraslan , Ülker Çötelioğlu Y1 - 2017 PY - 2017 N1 - doi: 10.30704/http-www-jivs-net.311279 DO - 10.30704/http-www-jivs-net.311279 T2 - Journal of Istanbul Veterinary Sciences JF - Journal JO - JOR SP - 16 EP - 27 VL - 1 IS - 1 SN - 2602-3490-2602-3490 M3 - doi: 10.30704/http-www-jivs-net.311279 UR - https://doi.org/10.30704/http-www-jivs-net.311279 Y2 - 2019 ER -
EndNote %0 Journal of Istanbul Veterinary Sciences Biology of procalcitonin and its potential role in veterinary medicine %A Erdal Matur , Evren Eraslan , Ülker Çötelioğlu %T Biology of procalcitonin and its potential role in veterinary medicine %D 2017 %J Journal of Istanbul Veterinary Sciences %P 2602-3490-2602-3490 %V 1 %N 1 %R doi: 10.30704/http-www-jivs-net.311279 %U 10.30704/http-www-jivs-net.311279
ISNAD Matur, Erdal , Eraslan, Evren , Çötelioğlu, Ülker . "Biology of procalcitonin and its potential role in veterinary medicine". Journal of Istanbul Veterinary Sciences 1 / 1 (April 2017): 16-27. https://doi.org/10.30704/http-www-jivs-net.311279