Year 2018, Volume 8, Issue 1, Pages 51 - 58 2018-03-30

Seroprevalence of Antibodies for Rubella and Cytomegalovirus among Pregnant and Antenatal Females in Western Turkey
Seroprevalence of Antibodies for Rubella and Cytomegalovirus among Pregnant and Antenatal Females in Western Turkey

Serdar GÜNGÖR [1] , Berrin UZUN [2]

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Primary infections caused by rubella and cytomegalovirus (CMV) can lead to serious complications due to their potentially teratogenic effects during pregnancy. Rubella and CMV screening of pregnant females is not routinely carried out in Turkey. The purpose of this study was to determine the prevalence of rubella and cytomegalovirus in Izmir among pregnant and antenatal females, and to review seroprevalences reported from different regions of Turkey.

Between January 2011 and December 2015, we retrospectively evaluated anti-rubella antibodies and anti-CMV antibodies of pregnant and antenatal females. Females aged 18-45  years were included in the study. Rubella and CMV IgM and G antibodies were tested using the IMMULITE® 2000XPi İmmunoassay System. Rubella IgG and rubella IgM seropositivity were detected in 16,255 (96.5%) of 16,845 and in 206 (1.1%) of the 18,720 pregnant and antenatal females, respectively. Positivity for the anti-CMV IgG and anti-CMV IgM antibody were found in 11,950 (98.7%) and 40 (0.3%) of 13,412 females. In conclusion, this study showed that in our province, a high percentage of pregnant and antenatal females had been exposed to rubella and CMV prior to reaching a child-bearing age. Rubella and CMV seroprevalences show a relatively homogeneous distribution throughout Turkey.

Primary infections caused by rubella and cytomegalovirus (CMV) can lead to serious complications due to their potentially teratogenic effects during pregnancy. Rubella and CMV screening of pregnant females is not routinely carried out in Turkey. The purpose of this study was to determine the prevalence of rubella and cytomegalovirus in Izmir among pregnant and antenatal females, and to review seroprevalences reported from different regions of Turkey.

Between January 2011 and December 2015, we retrospectively evaluated anti-rubella antibodies and anti-CMV antibodies of pregnant and antenatal females. Females aged 18-45  years were included in the study. Rubella and CMV IgM and G antibodies were tested using the IMMULITE® 2000XPi İmmunoassay System. Rubella IgG and rubella IgM seropositivity were detected in 16,255 (96.5%) of 16,845 and in 206 (1.1%) of the 18,720 pregnant and antenatal females, respectively. Positivity for the anti-CMV IgG and anti-CMV IgM antibody were found in 11,950 (98.7%) and 40 (0.3%) of 13,412 females. In conclusion, this study showed that in our province, a high percentage of pregnant and antenatal females had been exposed to rubella and CMV prior to reaching a child-bearing age. Rubella and CMV seroprevalences show a relatively homogeneous distribution throughout Turkey.

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Author: Serdar GÜNGÖR (Primary Author)

Author: Berrin UZUN

Bibtex @research article { jocrehes410779, journal = {Journal of Current Researches on Health Sector}, issn = {}, eissn = {2547-9636}, address = {Stratejik Araştırmalar Merkezi}, year = {2018}, volume = {8}, pages = {51 - 58}, doi = {}, title = {Seroprevalence of Antibodies for Rubella and Cytomegalovirus among Pregnant and Antenatal Females in Western Turkey}, key = {cite}, author = {GÜNGÖR, Serdar and UZUN, Berrin} }
APA GÜNGÖR, S , UZUN, B . (2018). Seroprevalence of Antibodies for Rubella and Cytomegalovirus among Pregnant and Antenatal Females in Western Turkey. Journal of Current Researches on Health Sector, 8 (1), 51-58. Retrieved from http://dergipark.org.tr/jocrehes/issue/36336/410779
MLA GÜNGÖR, S , UZUN, B . "Seroprevalence of Antibodies for Rubella and Cytomegalovirus among Pregnant and Antenatal Females in Western Turkey". Journal of Current Researches on Health Sector 8 (2018): 51-58 <http://dergipark.org.tr/jocrehes/issue/36336/410779>
Chicago GÜNGÖR, S , UZUN, B . "Seroprevalence of Antibodies for Rubella and Cytomegalovirus among Pregnant and Antenatal Females in Western Turkey". Journal of Current Researches on Health Sector 8 (2018): 51-58
RIS TY - JOUR T1 - Seroprevalence of Antibodies for Rubella and Cytomegalovirus among Pregnant and Antenatal Females in Western Turkey AU - Serdar GÜNGÖR , Berrin UZUN Y1 - 2018 PY - 2018 N1 - DO - T2 - Journal of Current Researches on Health Sector JF - Journal JO - JOR SP - 51 EP - 58 VL - 8 IS - 1 SN - -2547-9636 M3 - UR - Y2 - 2019 ER -
EndNote %0 Journal of Current Researches on Health Sector Seroprevalence of Antibodies for Rubella and Cytomegalovirus among Pregnant and Antenatal Females in Western Turkey %A Serdar GÜNGÖR , Berrin UZUN %T Seroprevalence of Antibodies for Rubella and Cytomegalovirus among Pregnant and Antenatal Females in Western Turkey %D 2018 %J Journal of Current Researches on Health Sector %P -2547-9636 %V 8 %N 1 %R %U
ISNAD GÜNGÖR, Serdar , UZUN, Berrin . "Seroprevalence of Antibodies for Rubella and Cytomegalovirus among Pregnant and Antenatal Females in Western Turkey". Journal of Current Researches on Health Sector 8 / 1 (March 2018): 51-58.