Year 2016, Volume 3, Issue 3, Pages 491 - 500 2017-01-08

INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN

Ruken Esra Demirdöğen [1] , Fatih Mehmet Emen [2] , Derya Kilic [3] , Gokturk Avsar [4] , Tuncay Yesilkaynak [5] , Tunay Askar [6]

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The target of this study is to determine the interrelation among serum Li level on bone metabolism (Ca, P, Parathormon, and Vitamin-D), sex and metabolic hormones (estrogen, FSH, LH and TSH), and some biochemical parameters in premenopausal and postmenopausal women. The study is carried out with 10 women: 5 premenopausal and 5 postmenopausal women. The serum Li levels, bone metabolism indicators (i.e., ALP, Ca, P, Mg, Cu, Zn) and some biochemical parameters such as serum tryglyceride, alkalene phosphatase, total cholesterol, HDL, LDL and cholesterol levels were determined. The estrogen blood level of women in menopause period was found to be lower than that of women in pre-menopause period (p<0.01) and the FSH level was found to be higher (p<0.01). In the lipid profile the triglyceride level in the post-menopause period was found to be low (p<0.05) and HDL (p<0.001), LDL (p<0.001) and the cholesterol levels were found to be high (p<0.001). The alkalene phosphatase (p<0.001) and Vitamin-D levels (p<0.001) were found to decrease. When the mineral levels were investigated no meaningful difference was observed in the serum magnesium and copper levels while zinc (p<0.01) and phosphorus (p<0.005) levels were observed to increase, the calcium levels (p<0.05) decreased and Li levels considerably decreased (p<0.0001). According to the results obtained it was determined for the first time that Li defficiency can be related with menopause and the related diseases and thus Li therapy can be used in developing new treatment protocols of menopause as an alternative method.

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Journal Section Articles
Authors

Author: Ruken Esra Demirdöğen

Author: Fatih Mehmet Emen

Author: Derya Kilic

Author: Gokturk Avsar

Author: Tuncay Yesilkaynak

Author: Tunay Askar

Dates

Publication Date: January 8, 2017

Bibtex @ { jotcsa287289, journal = {Journal of the Turkish Chemical Society Section A: Chemistry}, issn = {}, eissn = {2149-0120}, address = {Turkish Chemical Society}, year = {2017}, volume = {3}, pages = {491 - 500}, doi = {10.18596/jotcsa.29558}, title = {INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN}, key = {cite}, author = {Demirdöğen, Ruken Esra and Emen, Fatih Mehmet and Kilic, Derya and Avsar, Gokturk and Yesilkaynak, Tuncay and Askar, Tunay} }
APA Demirdöğen, R , Emen, F , Kilic, D , Avsar, G , Yesilkaynak, T , Askar, T . (2017). INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN. Journal of the Turkish Chemical Society Section A: Chemistry, 3 (3), 491-500. DOI: 10.18596/jotcsa.29558
MLA Demirdöğen, R , Emen, F , Kilic, D , Avsar, G , Yesilkaynak, T , Askar, T . "INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN". Journal of the Turkish Chemical Society Section A: Chemistry 3 (2017): 491-500 <http://dergipark.org.tr/jotcsa/issue/27290/287289?publisher=turchemsoc?publisher=turchemsoc>
Chicago Demirdöğen, R , Emen, F , Kilic, D , Avsar, G , Yesilkaynak, T , Askar, T . "INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN". Journal of the Turkish Chemical Society Section A: Chemistry 3 (2017): 491-500
RIS TY - JOUR T1 - INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN AU - Ruken Esra Demirdöğen , Fatih Mehmet Emen , Derya Kilic , Gokturk Avsar , Tuncay Yesilkaynak , Tunay Askar Y1 - 2017 PY - 2017 N1 - doi: 10.18596/jotcsa.29558 DO - 10.18596/jotcsa.29558 T2 - Journal of the Turkish Chemical Society Section A: Chemistry JF - Journal JO - JOR SP - 491 EP - 500 VL - 3 IS - 3 SN - -2149-0120 M3 - doi: 10.18596/jotcsa.29558 UR - https://doi.org/10.18596/jotcsa.29558 Y2 - 2019 ER -
EndNote %0 Journal of the Turkish Chemical Society Section A: Chemistry INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN %A Ruken Esra Demirdöğen , Fatih Mehmet Emen , Derya Kilic , Gokturk Avsar , Tuncay Yesilkaynak , Tunay Askar %T INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN %D 2017 %J Journal of the Turkish Chemical Society Section A: Chemistry %P -2149-0120 %V 3 %N 3 %R doi: 10.18596/jotcsa.29558 %U 10.18596/jotcsa.29558
ISNAD Demirdöğen, Ruken Esra , Emen, Fatih Mehmet , Kilic, Derya , Avsar, Gokturk , Yesilkaynak, Tuncay , Askar, Tunay . "INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN". Journal of the Turkish Chemical Society Section A: Chemistry 3 / 3 (January 2017): 491-500. https://doi.org/10.18596/jotcsa.29558
AMA Demirdöğen R , Emen F , Kilic D , Avsar G , Yesilkaynak T , Askar T . INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN. JOTCSA. 2017; 3(3): 491-500.
Vancouver Demirdöğen R , Emen F , Kilic D , Avsar G , Yesilkaynak T , Askar T . INTERRELATION AMONG SERUM LITHIUM LEVELS AND BONE METABOLISM AND SOME BIOCHEMICAL PARAMETERS IN PRE AND POST-MENAUPOSAL WOMEN. Journal of the Turkish Chemical Society Section A: Chemistry. 2017; 3(3): 500-491.