Novel probes for selective fluorometric sensing of Fe(II) and Fe(III) based on BODIPY dyes

Year 2019, Volume: 6 Issue: 2, 207 - 216, 15.06.2019

Elif Şenkuytu , Elif Okutan

https://doi.org/10.18596/jotcsa.488181

Cited By: 3

Abstract

Two novel
boron-dipyrromethene (BODIPY) based fluorescence turn-off sensors, which
demonstrate high selectivity and sensitivity toward Fe²⁺ and Fe³⁺
ions have been reported. A simple and high yielded synthesis of
fluorescent BODIPY derivatives with malonyl unit for sensitization have been
described. This approach provides quick, high yielded and low-cost preparation
of probes. The two sensors have been comprised of combination of one and two
BODIPY fluorophore and a malonyl unit, substituted on meso position of BODIPYs.
Synthesized BODIPY derivatives have been characterized via elemental analyses,
mass spectrometry, ¹H and ¹³C spectroscopy and their
photophyisical properties were investigated by UV- Vis absorption and
fluorescence emission spectroscopy.  The
synthesized sensors (2, 3) have been
used as a fluorescent probe towards the selective and sensitive detection of
biologically important Fe²⁺ and Fe³⁺ ions in
tetrahydrofuran by fluorescence spectroscopy. The limit of detection (LOD) have
been calculated to be for the BODIPY 2,
14.61 (Fe²⁺), 1.22 (Fe³⁺) and for BODIPY 3, 1.16 (Fe²⁺) and 1.06 (Fe³⁺).

Keywords

Borondipyrromethenes, UV-Vis spectroscopy, fluorescence, chemosensor

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