Year 2019, Volume 4, Issue 1, Pages 37 - 40 2019-06-30

İkiz Alman Holştayn Buzağıda Hidrosefali Internus, Diğer Sinirsel Malformasyonlar ve Kısa Kuyrukluluk Olgusu
Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves

Zafer USTA [1] , Ottmar DISTL [2]

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İki günlük Alman Holştayn Buzağı deforma bir kafa şekli ile doğdu. Buzağı, klinik muayeneden kısa süre sonra dayanamadı ve öldü ve daha sonra nekropsiye verildi. Yapılan Patolojik-Anatomik inceleme neticesinde hidrosefali internus ve serebellar hemisferlerin atrofisi, serebellum hipoplazisi, servikal omurilikte siringomiyeli ve torasik omuriliğin kraniyal kısmı dâhil olmak üzere çoklu şekil bozuklukları, torasik spinal kordonun kaudal kısmında hidromyeli, beşinci ve yedinci torakal vertebra arasında görülen skolyoz ve bilateral keratitis görülen ikiz doğan iki günlük bir Alman Holştayn buzağıda bovine viral diyare (BVD) virüsü antikorları pozitif çıkan bu sonuç görülen anomaliler ile ilişkili olabiliceği kanısına varıldı. Brachyury (kısa kuyruk) ile karakterize diğer erkek buzağıda ve ikiz buzağıların annesi olan inekde yapılan ELISA testi neticesinde BVD virüs antikorları için pozitif olarak tespit edildi. BVD virüsünün gebeliğin erken evresindeki enfeksiyonu, dişi buzağının çoklu malformasyonundan ve erkek buzağıda brachury’sinden sorumlu olduğu varsayılabilir.

A two-days-old female German Holstein twin calf borned a deformed cranium. The calf was not able to endure and died shortly after the clinical examination and this calf was submitted to necropsy. Pathological-anatomical examination showed multiple malformations including hydrocephalus internus and atrophy of cerebellar hemispheres, hypoplasia of the cerebellum, syringomyelia in the cervical spinal cord and the cranial part of the thoracic spinal cord, hydromyelia in the caudal part of the thoracic spinal cord, scoliosis between the fifth and seventh thoracic vertebra and bilateral keratitis could be associated with a positive result for bovine viral diarrhoea (BVD) virus antibodies. Its male co-twin with brachyury and also dam of the twins were positive for BVD virus antibodies by ELİSA Test. Infection by BVD virus in an early stage of the pregnancy may be assumed to be responsible for the multiple malformations in the female twin and the brachyury of the male co-twin.

  • References1. Neogy (Ganguli) M, Neogy S, Upadhyay SN, Hazra J. A case of congenital hydrocephalus in a calf and its successful recovery. Explor Anim Med Res 2014; 4: 253-6.
  • 2. Leipold HW, Dennis SM. Congenital defects of the bovine central nervous system. Vet Clin North Am Food Anim Pract 1987; 3: 159-77. DOI.org/10.1016/S0749-0720(15)31188-9
  • 3. Herzog A. Pareys Lexikon der Syndrome, Erb und Zuchtkrankheiten der Haus und Nutztiere. Berlin: Parey, 2001
  • 4. Leech RW, Hauges CN, Christoferson LA. Hydrocephalus, congenital hydrocephalus. Aminal model: bovine hydrocephalus, congenital internal hydrocephalus, aqueductal stenosis. Am J Pathol 1978; 92: 567-70.
  • 5. Urman H, Grace O. Hereditary encephalomyopathy. A hydrocephalus syndrome in newborn calves. Cornell Vet 1964; 54: 229.
  • 6. Blackwell R, Knox J, Cobb EH. A hydrocephalic lethal in hereford cattle. J Hered 1959; 50: 143-8. DOI.org/10.1093/oxfordjournals.jhered.a106894
  • 7. Queiroz DJ, Dias DMP, Soares LMC, Bandarra MB, Vasconcelos RO, Alessi AC, Marques LC. Report of cerebellar hypoplasia in three calves. Braz J Vet Pathol 2013; 6: 26-30.
  • 8. Leipold HW, Hiraga T, Dennis SM. Congenital defects of the bovine central nervous system. Vet Clin North Am Food Anim Pract 1993; 9: 77-91. DOI.org/10.1016/S0749-0720(15)30673-3
  • 9. Leipold HW, Huston K, Dennis SM. Bovine congenital defects. Adv Vet Sci Comp Med 1983; 27: 197-271.
  • 10. Becher P, Thiel HJ. Pestivirus. Tidona CA. Darai G. Editör (s). In: The Springer Index of Viruses. P. 327-31. Berlin: Springer-Verlag Berlin Heidelberg; 2001.
  • 11. Badman RT, Mitchell G, Jones RT, Westbury HA. Association of bovine viral diarrhoea virus infection to hydranencephaly and other central nervous system lesions in perinatal calves. Aust Vet J 1981; 57: 306-7. DOI.org/10.1111/j.1751-0813.1981.tb05831.x
  • 12. Roeder PL, Jeffrey M, Cranwell MP. Pestivirus fetopathology in cattle: Changing sequelae with fetal maturation. Vet Rec 1986; 118:44–8. DOI: 10.1136/vr.118.2.44
  • 13. Hazıroğlu R. Pathological findings in calves with hydranencephaly. Vet J Ankara Univ 1990; 37: 269-85.
  • 14. Tunca R, Hazıroğlu R, Güvenç T, Kutsal O, Özsoy ŞY. Congenital cerebellar hypoplasia associated with BVD-MD virus infection in a naturally infected calf. Vet Arhiv 2006; 76: 453-60.
  • 15. Buck BC, Algermissen D, Kuiper H, Baumgärtner W, Distl O. Dandy-Walker-Syndrom, Hydrozephalus internus, Anurie, Syringomyelie, Skoliose und Palatoschisis bei einem Deutschen Holstein Kalb in Folge einer intrauterinen Bovinen Virus Diarrhoe-(BVD)-Virus-Infektion. Prakt Tierarzt 2009; 90: 1066-71.
  • 16. Lotfi A, Shahryar HA. The case report of taillessness in Iranian female calf. Asian J Anim Vet Adv 2009: 4: 47-51.
  • 17. Cole C, Moore L. Hydrocephalus, a lethal in cattle. J Agr Res 1942; 65: 483-91.
  • 18. Axthelm M, Leipold H, Phillips R. Congenital internal hydrocephalus in calves associated with bovine virus diarrhea-mucosal disease virus. Bovine Pract 1980; 1: 19-27.
  • 19. Hewicker-Trautwein M, Liess B, Trautwein G. Brain lesions in calves following transplacental infection with bovine-virus diarrhoea virus. Zbl Vet Med B 1995; 42: 65-77. DOI.org/10.1111/j.1439-0450.1995.tb00684.x
  • 20. Sakamoto K, Kiupel M, Frank N, March PA. Vertebral malformation, syringomyelia, and ventricular septal defect in a dromedary camel (Camelius dromedarius). J Vet Diagn Invest 2004; 16: 337–40. DOI.org/10.1177/104063870401600415
  • 21. Dutton CJ, Duncan M, Price HI. Hydromyelia in a Reeves Muntjac (Muntiacus Reevesi). J Zoo Wildlife Med 2002; 33: 256–62. DOI.org/10.1638/1042-7260(2002)033[0256:HIARMM]2.0.CO;2
  • 22. Sponseller BA, Sponseller BT, Alcott CJ, Kline K, Hostetter J, Reinertson EL, Williams AF. Syringohydromyelia in horses: 3 cases. Can Vet J 2011; 52: 147–52.
  • 23. Bistner SI, Rubin LF, Saunders LZ. The ocular lesions of Bovine Viral Diarrhea-Mucosal Disease. Pathol Vet 1970; 7: 275-86. DOI.org/10.1177/030098587000700306
  • 24. Kahrs RF, Scott FW, De Lahunta A. Epidemiological observations on bovine viral diarrhea-mucosal disease virus-induced congenital cerebellar hypoplasia and ocular defects in calves. Teratology 1970; 3: 181-4. DOI.org/10.1002/tera.1420030211
  • 25. Baker ML, Payne LC, Baker GN. Inheritance of hydrocephalus in cattle. J Hered 1961; 52: 135-8. DOI.org/10.1093/oxfordjournals.jhered.a107048
  • 26. Kahrs RF, Scott FW, de Lahunte A. Congenital cerebella hypoplasia and ocular defects in calves following bovine viral diarrhea-mucosal disease infection in pregnant cattle. J Am Vet Med Assoc 1970; 156: 1443-50.
  • 27. Lanyon SR, Hill FI, Reichel MP, Brownlie J. Bovine viral diarrhoea: pathogenesis and diagnosis. Vet J 2014; 199: 201-9. DOI.org/10.1016/j.tvjl.2013.07.024
Primary Language en
Subjects Health Care Sciences and Services
Journal Section Case Reports
Authors

Orcid: 0000-0003-2766-2349
Author: Zafer USTA (Primary Author)
Institution: MEHMET AKİF ERSOY ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ
Country: Turkey


Author: Ottmar DISTL
Country: Germany


Dates

Publication Date: June 30, 2019

Bibtex @case report { maeuvfd492354, journal = {Veterinary Journal of Mehmet Akif Ersoy University}, issn = {2458-9268}, eissn = {2148-6239}, address = {Mehmet Akif Ersoy University}, year = {2019}, volume = {4}, pages = {37 - 40}, doi = {10.24880/maeuvfd.492354}, title = {Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves}, key = {cite}, author = {USTA, Zafer and DISTL, Ottmar} }
APA USTA, Z , DISTL, O . (2019). Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves. Veterinary Journal of Mehmet Akif Ersoy University, 4 (1), 37-40. DOI: 10.24880/maeuvfd.492354
MLA USTA, Z , DISTL, O . "Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves". Veterinary Journal of Mehmet Akif Ersoy University 4 (2019): 37-40 <http://dergipark.org.tr/maeuvfd/issue/46573/492354>
Chicago USTA, Z , DISTL, O . "Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves". Veterinary Journal of Mehmet Akif Ersoy University 4 (2019): 37-40
RIS TY - JOUR T1 - Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves AU - Zafer USTA , Ottmar DISTL Y1 - 2019 PY - 2019 N1 - doi: 10.24880/maeuvfd.492354 DO - 10.24880/maeuvfd.492354 T2 - Veterinary Journal of Mehmet Akif Ersoy University JF - Journal JO - JOR SP - 37 EP - 40 VL - 4 IS - 1 SN - 2458-9268-2148-6239 M3 - doi: 10.24880/maeuvfd.492354 UR - https://doi.org/10.24880/maeuvfd.492354 Y2 - 2019 ER -
EndNote %0 Veterinary Journal of Mehmet Akif Ersoy University Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves %A Zafer USTA , Ottmar DISTL %T Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves %D 2019 %J Veterinary Journal of Mehmet Akif Ersoy University %P 2458-9268-2148-6239 %V 4 %N 1 %R doi: 10.24880/maeuvfd.492354 %U 10.24880/maeuvfd.492354
ISNAD USTA, Zafer , DISTL, Ottmar . "Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves". Veterinary Journal of Mehmet Akif Ersoy University 4 / 1 (June 2019): 37-40. https://doi.org/10.24880/maeuvfd.492354
AMA USTA Z , DISTL O . Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves. MAEU Vet. Fak. Derg.. 2019; 4(1): 37-40.
Vancouver USTA Z , DISTL O . Hydrocephalus Internus and other Neural Malformations, Brachyury in German Holstein Twin Calves. Veterinary Journal of Mehmet Akif Ersoy University. 2019; 4(1): 40-37.