Year 2019, Volume 4, Issue 1, Pages 8 - 13 2019-06-30

Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum

Hasan ERDOĞAN [1] , Mehmet GÜLTEKİN [2] , Kerem URAL [3] , Yasin PARLATIR [4] , Adnan AYAN [5] , Songul ERDOĞAN [6] , Serdar PAŞA [7]

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The aim of the present study was to evaluate the selected coagulation profile parameters in sheep naturally infected with Dicrocoeliumdentriticum and effects of albendazole treatmentFor this reason, 34 merino sheep, aged between 1 and 3 years, naturally infected with Dicrocoeliumdentriticumwere enrolled in the present study. Plasma and stool samples were withdrawn from each animal before and 10 days after treatment and egg per gram feces were evaluated with Mc Master technique. Prothrombin time activated partial thromboplastin time and fibrinogen levels were determined by semiautomated coagulometer by using commercial test kits before and 10 days after treatment.Noticeable clinical recovery was detected in all animals after albendazole treatment. There were significant differences on Prothrombin time and fibrinogen levels a p value of (p<0.001) between treatment intervals. In conclusion, this is the first study for selected coagulation parameters before and after albendazole treatment for ovine patients naturally infected with Dicrocoeliumdentriticum. It should be mentioned that the treatment resulted in lower prothrombin time and fibrinogen values, suggesting that dicrocoeliasis might alter coagulation profile and possibly induce an acute phase response. Furthermore, the clinical relevance in ovine medicine and related results possibly interacting to human medicine has to be determined by future studies.

Activated partial thromboplastin, anthelmintic, fibrinogen, liver fluke, prothrombin
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Primary Language en
Subjects Health Care Sciences and Services
Journal Section Research Articles
Authors

Orcid: 0000-0001-8109-8537
Author: Hasan ERDOĞAN
Institution: AYDIN ADNAN MENDERES ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK İÇ HASTALIKLARI ANABİLİM DALI
Country: Turkey


Orcid: 0000-0002-5197-2403
Author: Mehmet GÜLTEKİN
Institution: AYDIN ADNAN MENDERES ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK İÇ HASTALIKLARI ANABİLİM DALI
Country: Turkey


Orcid: 0000-0003-1867-7143
Author: Kerem URAL
Institution: ADNAN MENDERES ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK İÇ HASTALIKLARI ANABİLİM DALI
Country: Turkey


Orcid: 0000-0002-6210-8979
Author: Yasin PARLATIR
Institution: KIRIKKALE ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, HASTALIKLAR VE KLİNİK BİLİMLERİ BÖLÜMÜ, VETERİNERLİK İÇ HASTALIKLARI ANABİLİM DALI
Country: Turkey


Orcid: 0000-0002-6564-3416
Author: Adnan AYAN
Institution: VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, ZOOTEKNİ VE HAYVAN BESLEME BÖLÜMÜ, VETERİNERLİK GENETİĞİ ANABİLİM DALI

Orcid: 0000-0002-7833-5519
Author: Songul ERDOĞAN
Institution: AYDIN ADNAN MENDERES ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK İÇ HASTALIKLARI ANABİLİM DALI

Orcid: 0000-0003-4957-9263
Author: Serdar PAŞA
Institution: AYDIN ADNAN MENDERES ÜNİVERSİTESİ, VETERİNER FAKÜLTESİ, KLİNİK BİLİMLER BÖLÜMÜ, VETERİNERLİK İÇ HASTALIKLARI ANABİLİM DALI

Dates

Publication Date: June 30, 2019

Bibtex @research article { maeuvfd523108, journal = {Veterinary Journal of Mehmet Akif Ersoy University}, issn = {2458-9268}, eissn = {2148-6239}, address = {Mehmet Akif Ersoy University}, year = {2019}, volume = {4}, pages = {8 - 13}, doi = {10.24880/maeuvfd.523108}, title = {Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum}, key = {cite}, author = {ERDOĞAN, Hasan and GÜLTEKİN, Mehmet and URAL, Kerem and PARLATIR, Yasin and AYAN, Adnan and ERDOĞAN, Songul and PAŞA, Serdar} }
APA ERDOĞAN, H , GÜLTEKİN, M , URAL, K , PARLATIR, Y , AYAN, A , ERDOĞAN, S , PAŞA, S . (2019). Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum. Veterinary Journal of Mehmet Akif Ersoy University, 4 (1), 8-13. DOI: 10.24880/maeuvfd.523108
MLA ERDOĞAN, H , GÜLTEKİN, M , URAL, K , PARLATIR, Y , AYAN, A , ERDOĞAN, S , PAŞA, S . "Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum". Veterinary Journal of Mehmet Akif Ersoy University 4 (2019): 8-13 <http://dergipark.org.tr/maeuvfd/issue/46573/523108>
Chicago ERDOĞAN, H , GÜLTEKİN, M , URAL, K , PARLATIR, Y , AYAN, A , ERDOĞAN, S , PAŞA, S . "Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum". Veterinary Journal of Mehmet Akif Ersoy University 4 (2019): 8-13
RIS TY - JOUR T1 - Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum AU - Hasan ERDOĞAN , Mehmet GÜLTEKİN , Kerem URAL , Yasin PARLATIR , Adnan AYAN , Songul ERDOĞAN , Serdar PAŞA Y1 - 2019 PY - 2019 N1 - doi: 10.24880/maeuvfd.523108 DO - 10.24880/maeuvfd.523108 T2 - Veterinary Journal of Mehmet Akif Ersoy University JF - Journal JO - JOR SP - 8 EP - 13 VL - 4 IS - 1 SN - 2458-9268-2148-6239 M3 - doi: 10.24880/maeuvfd.523108 UR - https://doi.org/10.24880/maeuvfd.523108 Y2 - 2019 ER -
EndNote %0 Veterinary Journal of Mehmet Akif Ersoy University Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum %A Hasan ERDOĞAN , Mehmet GÜLTEKİN , Kerem URAL , Yasin PARLATIR , Adnan AYAN , Songul ERDOĞAN , Serdar PAŞA %T Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum %D 2019 %J Veterinary Journal of Mehmet Akif Ersoy University %P 2458-9268-2148-6239 %V 4 %N 1 %R doi: 10.24880/maeuvfd.523108 %U 10.24880/maeuvfd.523108
ISNAD ERDOĞAN, Hasan , GÜLTEKİN, Mehmet , URAL, Kerem , PARLATIR, Yasin , AYAN, Adnan , ERDOĞAN, Songul , PAŞA, Serdar . "Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum". Veterinary Journal of Mehmet Akif Ersoy University 4 / 1 (June 2019): 8-13. https://doi.org/10.24880/maeuvfd.523108
AMA ERDOĞAN H , GÜLTEKİN M , URAL K , PARLATIR Y , AYAN A , ERDOĞAN S , PAŞA S . Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum. MAEU Vet. Fak. Derg.. 2019; 4(1): 8-13.
Vancouver ERDOĞAN H , GÜLTEKİN M , URAL K , PARLATIR Y , AYAN A , ERDOĞAN S , PAŞA S . Evaluation of albendazole treatment on coagulation profile in sheep naturally infected with Dicrocoelium dentriticum. Veterinary Journal of Mehmet Akif Ersoy University. 2019; 4(1): 13-8.