Year 2018, Volume 8, Issue 3, Pages 154 - 159 2018-09-28

Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia?

Ilke Kupeli [1] , Ufuk Kuyrukluyıldız [2] , Sara Taş [3] , Zehra Bedir [4] , Ayşin Selcan [5]

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Objective: Peripheral nerve blocks are now used widely for postoperative analgesia

and peripheral nerve catheters are widely utilized. Objective of this study was to

investigate effect of perineural infusion of dexmedetomidine on the duration of

postoperative analgesia retrospectively.

Material & Methods: A total of 60 patients aged between 18 and 65 years were

included in the study. Group 1 received infraclavicular patient-controlled perineural

bupivacaine (0.1 %). Group 2 received infraclavicular patient-controlled perineural

bupivacaine (0.1 %) + dexmedetomidine (200 mic/100 cc). Blood pressure, pulse,

peripheral oxygen saturation modified ramsay sedation scale, visual pain scores, total

amount of analgesics were recorded at the 0, 30, 60, 90 minutes and 2, 4, 6, 8, 12,

24 hours.

Results: Systolic blood pressure was higher in Group 1 at the hour 6 (p: 0.007).

Whereas, diastolic blood pressure was higher in Group 1 at the hours 4 and 6 (p:

0.000, p: 0.003). Heart rate was found to be higher in Group 2 at the hours 8, 12 and

24 (p: 0.004, p: 0.002, p: 0.002). Patients in Group 1 were found to significantly feel

pain and need analgesics at the hours 4 and 6 (p: 0.002, p< 0.05). The mean number

of patient requests for analgesia was 5.8±1.4 times in Group 1 and 2.2±0.4 in Group

2 (p<0,05). None of the patients developed sedation/neurological deficits.

Conclusion: Perineural infusion of dexmedetomidine combined with bupivacaine

was found to increase the duration of postoperative analgesia, reduce 24-hour need

for analgesia and have not any adverse efect at low doses.

Patient-Controlled Analgesia; Perineural Dexmedetomidine infusion; Duration of Postoperative Analgesia
  • Liu SS. A comparison of regional versus general anesthesia for ambulatory anesthesia: a meta-analysis of randomized controlled trials. Anesth Analg 2005; 101: 1634–42.
Primary Language en
Subjects Health Care Sciences and Services
Journal Section Articles
Authors

Author: Ilke Kupeli

Author: Ufuk Kuyrukluyıldız

Author: Sara Taş

Author: Zehra Bedir

Author: Ayşin Selcan

Dates

Publication Date: September 28, 2018

Bibtex @research article { marusbed465481, journal = {Clinical and Experimental Health Sciences}, issn = {}, eissn = {2459-1459}, address = {Marmara University}, year = {2018}, volume = {8}, pages = {154 - 159}, doi = {10.5152/clinexphealthsci.2017.413}, title = {Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia?}, key = {cite}, author = {Kupeli, Ilke and Kuyrukluyıldız, Ufuk and Taş, Sara and Bedir, Zehra and Selcan, Ayşin} }
APA Kupeli, I , Kuyrukluyıldız, U , Taş, S , Bedir, Z , Selcan, A . (2018). Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia?. Clinical and Experimental Health Sciences, 8 (3), 154-159. DOI: 10.5152/clinexphealthsci.2017.413
MLA Kupeli, I , Kuyrukluyıldız, U , Taş, S , Bedir, Z , Selcan, A . "Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia?". Clinical and Experimental Health Sciences 8 (2018): 154-159 <http://dergipark.org.tr/marusbed/issue/39474/465481>
Chicago Kupeli, I , Kuyrukluyıldız, U , Taş, S , Bedir, Z , Selcan, A . "Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia?". Clinical and Experimental Health Sciences 8 (2018): 154-159
RIS TY - JOUR T1 - Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia? AU - Ilke Kupeli , Ufuk Kuyrukluyıldız , Sara Taş , Zehra Bedir , Ayşin Selcan Y1 - 2018 PY - 2018 N1 - doi: 10.5152/clinexphealthsci.2017.413 DO - 10.5152/clinexphealthsci.2017.413 T2 - Clinical and Experimental Health Sciences JF - Journal JO - JOR SP - 154 EP - 159 VL - 8 IS - 3 SN - -2459-1459 M3 - doi: 10.5152/clinexphealthsci.2017.413 UR - https://doi.org/10.5152/clinexphealthsci.2017.413 Y2 - 2019 ER -
EndNote %0 Clinical and Experimental Health Sciences Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia? %A Ilke Kupeli , Ufuk Kuyrukluyıldız , Sara Taş , Zehra Bedir , Ayşin Selcan %T Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia? %D 2018 %J Clinical and Experimental Health Sciences %P -2459-1459 %V 8 %N 3 %R doi: 10.5152/clinexphealthsci.2017.413 %U 10.5152/clinexphealthsci.2017.413
ISNAD Kupeli, Ilke , Kuyrukluyıldız, Ufuk , Taş, Sara , Bedir, Zehra , Selcan, Ayşin . "Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia?". Clinical and Experimental Health Sciences 8 / 3 (September 2018): 154-159. https://doi.org/10.5152/clinexphealthsci.2017.413
AMA Kupeli I , Kuyrukluyıldız U , Taş S , Bedir Z , Selcan A . Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia?. Clinical and Experimental Health Sciences. 2018; 8(3): 154-159.
Vancouver Kupeli I , Kuyrukluyıldız U , Taş S , Bedir Z , Selcan A . Does Patient-Controlled Infraclavicular Perineural Dexmedetomidine Increase the Duration of Postoperative Analgesia?. Clinical and Experimental Health Sciences. 2018; 8(3): 159-154.