Fine needle aspiration cytology (FNAC) of cystic soft tissue lesions and end tissue metamorphosis-a three year study

Yıl 2019, Cilt: 6 Sayı: 3, 46 - 53, 30.03.2019

Ragini Thapa Rajveer Singh Beniwal Prosenjit Ganguly

https://doi.org/10.17546/msd.536237

Öz

Objective: Superficial soft-tissue masses may be seen in clinical practice, but a
systematic approach may help to achieve a definitive diagnosis or differential
diagnosis for soft tissue lesions. The cystic lesions constitute a
heterogeneous group with highly varied etiology, cytology and diversified
histopathology. The aim of this study is to investigate the accuracy of FNAC
diagnosis of varied cystic lesions of soft tissue lesions by comparing with the
radiological and histopathology diagnosis.

Materials and
methods: Fine needle aspirations were done using a 22-24 gauge disposable needle and a 5cc to 10 cc
disposable syringe for suction. Wet-fixed smears with isopropyl alcohol were
stained with hematoxylin and eosin (HxE). Dry-fixed smears were stained with Leishman
Giemsa along with Papanicolaou stains (PAP) were studied for cytological
details and diagnosis. The excised surgical specimen and biopsy samples of the
cases were processed routinely and stained with HxE and immunohistochemistry
(IHC) panel was applied.

Results: Examined cystic soft-tissue masses were found as superficial (82%) and
deep (18%). Superficial lesions were categorized into mesenchymal tumors, skin
appendage lesions, tumor like lesions, pseudoudo tumoural soft tissue lesions
or parasitic /inflammatory lesions. Deeper lesions with cystic presentation
were mostly (74%) malignant. The differential diagnosis was done according to
the age of the patient, anatomic location of the lesion, salient imaging
features and clinical manifestations.

Conclusion: Although the fine
needle aspiration cytology of the cystic lesions, imaging characteristics of
the lesions discussed are not always corresponding to the histopathologic
findings what we assume, combining them with lesion location and clinical
features may allow the diagnosticians to suggest a specific diagnosis in most
cases.

Anahtar Kelimeler

FNAC, Cystic soft tissue lesions

Kaynakça

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