Year 2012, Volume 42, Issue 3, Pages 395 - 401 2012-03-01

Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy
Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy

Yasemin ŞAHİN [1] , Alparslan APAN [2] , Gökşen ÖZ [3] , Çetin Ayhan EVLİYAOĞLU [4]

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To investigate the postoperative analgesic effects of epidural tramadol infiltration. Tramadol is a weak opioid that has local anesthetic and antiinflammatory properties. Materials and methods: Sixty patients of American Society of Anesthesiologists class I or II undergoing lumbar microdiscectomy with general anesthesia were included in the study. The induction of anesthesia was performed with propofol (2-2.5 mg kg-1, rocuronium bromide (0.5 mg kg-1), and fentanyl (1 µg kg-1). A sevoflurane and N2O/O2 (FiO2 = 35%) mixture was used for maintenance. Patients were randomly divided into 2 groups. Tramadol (1 mg kg-1) in a 5-mL saline epidural infiltration was given in the study group at the end of the operation, before surgical closure, and saline in the same volume was given to the control group. Pain was assessed by a visual analog scale (0 to 10 cm) at 4-h intervals during the first postoperative 24 h. A patient-controlled analgesia (PCA) device was adjusted to deliver fentanyl (15 µg bolus) on demand, with a 10-min lockout interval. Results: No significant difference was found in the visual analog scales between the groups. Tramadol infiltration significantly decreased fentanyl consumption in the first 24 h (fentanyl dose in the control group: 328.5 ± 221.8 µg, tramadol group: 194.5 ± 147.4 µg, P = 0.030). The number of demands for PCA were 51.2 ± 77.9 and 20.1 ± 23.7 in the control and the tramadol groups, respectively (P = 0.02). No difference was found in side-effect profiles between the groups. Conclusion: Tramadol administration to the epidural space significantly decreased analgesic consumption in patients undergoing microdiscectomy.
To investigate the postoperative analgesic effects of epidural tramadol infiltration. Tramadol is a weak opioid that has local anesthetic and antiinflammatory properties. Materials and methods: Sixty patients of American Society of Anesthesiologists class I or II undergoing lumbar microdiscectomy with general anesthesia were included in the study. The induction of anesthesia was performed with propofol (2-2.5 mg kg-1, rocuronium bromide (0.5 mg kg-1), and fentanyl (1 µg kg-1). A sevoflurane and N2O/O2 (FiO2 = 35%) mixture was used for maintenance. Patients were randomly divided into 2 groups. Tramadol (1 mg kg-1) in a 5-mL saline epidural infiltration was given in the study group at the end of the operation, before surgical closure, and saline in the same volume was given to the control group. Pain was assessed by a visual analog scale (0 to 10 cm) at 4-h intervals during the first postoperative 24 h. A patient-controlled analgesia (PCA) device was adjusted to deliver fentanyl (15 µg bolus) on demand, with a 10-min lockout interval. Results: No significant difference was found in the visual analog scales between the groups. Tramadol infiltration significantly decreased fentanyl consumption in the first 24 h (fentanyl dose in the control group: 328.5 ± 221.8 µg, tramadol group: 194.5 ± 147.4 µg, P = 0.030). The number of demands for PCA were 51.2 ± 77.9 and 20.1 ± 23.7 in the control and the tramadol groups, respectively (P = 0.02). No difference was found in side-effect profiles between the groups. Conclusion: Tramadol administration to the epidural space significantly decreased analgesic consumption in patients undergoing microdiscectomy.
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Primary Language tr
Journal Section Articles
Authors

Author: Yasemin ŞAHİN

Author: Alparslan APAN

Author: Gökşen ÖZ

Author: Çetin Ayhan EVLİYAOĞLU

Dates

Publication Date: March 1, 2012

Bibtex @ { tbtkmedical147101, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {TUBITAK}, year = {2012}, volume = {42}, pages = {395 - 401}, doi = {}, title = {Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy}, key = {cite}, author = {ŞAHİN, Yasemin and APAN, Alparslan and ÖZ, Gökşen and EVLİYAOĞLU, Çetin Ayhan} }
APA ŞAHİN, Y , APAN, A , ÖZ, G , EVLİYAOĞLU, Ç . (2012). Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy. Turkish Journal of Medical Sciences, 42 (3), 395-401. Retrieved from http://dergipark.org.tr/tbtkmedical/issue/12298/147101
MLA ŞAHİN, Y , APAN, A , ÖZ, G , EVLİYAOĞLU, Ç . "Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy". Turkish Journal of Medical Sciences 42 (2012): 395-401 <http://dergipark.org.tr/tbtkmedical/issue/12298/147101>
Chicago ŞAHİN, Y , APAN, A , ÖZ, G , EVLİYAOĞLU, Ç . "Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy". Turkish Journal of Medical Sciences 42 (2012): 395-401
RIS TY - JOUR T1 - Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy AU - Yasemin ŞAHİN , Alparslan APAN , Gökşen ÖZ , Çetin Ayhan EVLİYAOĞLU Y1 - 2012 PY - 2012 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 395 EP - 401 VL - 42 IS - 3 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2019 ER -
EndNote %0 Turkish Journal of Medical Sciences Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy %A Yasemin ŞAHİN , Alparslan APAN , Gökşen ÖZ , Çetin Ayhan EVLİYAOĞLU %T Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy %D 2012 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 42 %N 3 %R %U
ISNAD ŞAHİN, Yasemin , APAN, Alparslan , ÖZ, Gökşen , EVLİYAOĞLU, Çetin Ayhan . "Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy". Turkish Journal of Medical Sciences 42 / 3 (March 2012): 395-401.
AMA ŞAHİN Y , APAN A , ÖZ G , EVLİYAOĞLU Ç . Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy. Turkish Journal of Medical Sciences. 2012; 42(3): 395-401.
Vancouver ŞAHİN Y , APAN A , ÖZ G , EVLİYAOĞLU Ç . Epidural tramadol infiltration decreases postoperative analgesic consumption after lumbar microdiscectomy. Turkish Journal of Medical Sciences. 2012; 42(3): 401-395.