Year 2012, Volume 42, Issue 3, Pages 417 - 424 2012-03-01

Relation between aortic stiffness and extension of coronary artery disease
Relation between aortic stiffness and extension of coronary artery disease

Ömer ŞATIROĞLU [1] , Mehmet BOSTAN [2] , Nermin BAYAR [3] , Yüksel ÇİÇEK [4]

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To investigate the relation between aortic stiffness and the extension/severity of coronary artery disease (CAD). Materials and methods: A consecutive 100 patients with suspicion of CAD who underwent elective coronary angiography were enrolled in this study. Of those patients determined as having CAD, 63 were classified as Group I (mean age: 62.1 ± 10.3 years; 47 male and 16 female). Group II included 37 patients with normal coronary arteries (mean age: 51.4 ± 10.8 years; 20 male and 17 female). Aortic flexibility (aortic distensibility and stiffness index) was evaluated by echocardiography after coronary angiography in all of the patients. Patient data were gathered in relation to age, sex, and atherosclerotic risk factors. Stenosis above 50% was accepted as severe CAD. The extension of coronary artery disease was determined using the Gensini score. Results: The mean age (62.1 ± 10.3 and 51.4 ± 10.8, respectively) and the male/female rate in Group I were higher than in Group II (P < 0.001 and P = 0.035, respectively). The mean aortic stiffness in Group I was significantly increased compared to Group II (8.9 ± 5.1 mm and 6.1 ± 4.6 mm, respectively; P = 0.001), whereas the mean aortic distensibility in Group I was significantly lower than in Group II (23.4 ± 16.5 mm and 42.4 ± 27.1 mm, respectively; P < 0.001). The aortic stiffness index increased and distensibility decreased in correlation with age, coronary artery risk factors, and extension of CAD. Conclusion: The aortic stiffness index increased and distensibility decreased in correlation with CAD extension and the number of affected coronary arteries.
To investigate the relation between aortic stiffness and the extension/severity of coronary artery disease (CAD). Materials and methods: A consecutive 100 patients with suspicion of CAD who underwent elective coronary angiography were enrolled in this study. Of those patients determined as having CAD, 63 were classified as Group I (mean age: 62.1 ± 10.3 years; 47 male and 16 female). Group II included 37 patients with normal coronary arteries (mean age: 51.4 ± 10.8 years; 20 male and 17 female). Aortic flexibility (aortic distensibility and stiffness index) was evaluated by echocardiography after coronary angiography in all of the patients. Patient data were gathered in relation to age, sex, and atherosclerotic risk factors. Stenosis above 50% was accepted as severe CAD. The extension of coronary artery disease was determined using the Gensini score. Results: The mean age (62.1 ± 10.3 and 51.4 ± 10.8, respectively) and the male/female rate in Group I were higher than in Group II (P < 0.001 and P = 0.035, respectively). The mean aortic stiffness in Group I was significantly increased compared to Group II (8.9 ± 5.1 mm and 6.1 ± 4.6 mm, respectively; P = 0.001), whereas the mean aortic distensibility in Group I was significantly lower than in Group II (23.4 ± 16.5 mm and 42.4 ± 27.1 mm, respectively; P < 0.001). The aortic stiffness index increased and distensibility decreased in correlation with age, coronary artery risk factors, and extension of CAD. Conclusion: The aortic stiffness index increased and distensibility decreased in correlation with CAD extension and the number of affected coronary arteries.
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Primary Language tr
Subjects
Journal Section Articles
Authors

Author: Ömer ŞATIROĞLU

Author: Mehmet BOSTAN

Author: Nermin BAYAR

Author: Yüksel ÇİÇEK

Bibtex @ { tbtkmedical147104, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {TUBITAK}, year = {2012}, volume = {42}, pages = {417 - 424}, doi = {}, title = {Relation between aortic stiffness and extension of coronary artery disease}, key = {cite}, author = {ŞATIROĞLU, Ömer and BOSTAN, Mehmet and BAYAR, Nermin and ÇİÇEK, Yüksel} }
APA ŞATIROĞLU, Ö , BOSTAN, M , BAYAR, N , ÇİÇEK, Y . (2012). Relation between aortic stiffness and extension of coronary artery disease. Turkish Journal of Medical Sciences, 42 (3), 417-424. Retrieved from http://dergipark.org.tr/tbtkmedical/issue/12298/147104
MLA ŞATIROĞLU, Ö , BOSTAN, M , BAYAR, N , ÇİÇEK, Y . "Relation between aortic stiffness and extension of coronary artery disease". Turkish Journal of Medical Sciences 42 (2012): 417-424 <http://dergipark.org.tr/tbtkmedical/issue/12298/147104>
Chicago ŞATIROĞLU, Ö , BOSTAN, M , BAYAR, N , ÇİÇEK, Y . "Relation between aortic stiffness and extension of coronary artery disease". Turkish Journal of Medical Sciences 42 (2012): 417-424
RIS TY - JOUR T1 - Relation between aortic stiffness and extension of coronary artery disease AU - Ömer ŞATIROĞLU , Mehmet BOSTAN , Nermin BAYAR , Yüksel ÇİÇEK Y1 - 2012 PY - 2012 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 417 EP - 424 VL - 42 IS - 3 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2019 ER -
EndNote %0 Turkish Journal of Medical Sciences Relation between aortic stiffness and extension of coronary artery disease %A Ömer ŞATIROĞLU , Mehmet BOSTAN , Nermin BAYAR , Yüksel ÇİÇEK %T Relation between aortic stiffness and extension of coronary artery disease %D 2012 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 42 %N 3 %R %U
ISNAD ŞATIROĞLU, Ömer , BOSTAN, Mehmet , BAYAR, Nermin , ÇİÇEK, Yüksel . "Relation between aortic stiffness and extension of coronary artery disease". Turkish Journal of Medical Sciences 42 / 3 (March 2012): 417-424.