Year 2012, Volume 42, Issue 3, Pages 497 - 505 2012-03-01

Clinical appearance of brucellosis in adults: fourteen years of experience
Clinical appearance of brucellosis in adults: fourteen years of experience

Behice KURTARAN [1] , Aslıhan CANDEVİR [2] , Ayşe Seza İNAL [3] , Süheyla KÖMÜR [4] , Özay AKYILDIZ [5] , Neşe SALTOĞLU [6] , Hasan Salih Zeki AKSU [7] , Yeşim TAŞOVA [8]

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To indicate the clinical course and results of brucellosis in our region during the recent years, and to compare these findings to the literature. Materials and methods: This study was based on a review of the medical records of adult patients older than 14 years who were followed with the diagnosis of brucellosis from March 1997 to October 2010. Results: Included in this analysis were 317 patients, including 136 males (43%), with an average age of 40 ± 17 years. In 66 patients (21%), reproduction of Brucella was identified in the blood. Of the patients, 61% were identified as having the acute form, 35% the subacute form, and 4% the chronic form. Arthralgia, fever, weight loss, sacroiliitis, and spondylitis were the most frequent symptoms and findings accompanying the disease. There was a significant relationship between advanced age and the development of both spondylitis and arthritis (P = 0.000 and P = 0.028, respectively). Furthermore, there was a significant relationship between a high erythrocyte sedimentation rate and the presence of spondylitis, sacroiliitis, and visceral abscesses (P = 0.001, P = 0.013, and P = 0.049, respectively). Conclusion: This study provides a review of the disease and its complications. Osteoarticular involvement, and particularly the presence of spondylitis in patients and the complications in elderly patients, should be studied. Laboratory parameters, the patient's age, and the duration of symptoms may help to identify complicated cases.
To indicate the clinical course and results of brucellosis in our region during the recent years, and to compare these findings to the literature. Materials and methods: This study was based on a review of the medical records of adult patients older than 14 years who were followed with the diagnosis of brucellosis from March 1997 to October 2010. Results: Included in this analysis were 317 patients, including 136 males (43%), with an average age of 40 ± 17 years. In 66 patients (21%), reproduction of Brucella was identified in the blood. Of the patients, 61% were identified as having the acute form, 35% the subacute form, and 4% the chronic form. Arthralgia, fever, weight loss, sacroiliitis, and spondylitis were the most frequent symptoms and findings accompanying the disease. There was a significant relationship between advanced age and the development of both spondylitis and arthritis (P = 0.000 and P = 0.028, respectively). Furthermore, there was a significant relationship between a high erythrocyte sedimentation rate and the presence of spondylitis, sacroiliitis, and visceral abscesses (P = 0.001, P = 0.013, and P = 0.049, respectively). Conclusion: This study provides a review of the disease and its complications. Osteoarticular involvement, and particularly the presence of spondylitis in patients and the complications in elderly patients, should be studied. Laboratory parameters, the patient's age, and the duration of symptoms may help to identify complicated cases.
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Primary Language tr
Journal Section Articles
Authors

Author: Behice KURTARAN

Author: Aslıhan CANDEVİR

Author: Ayşe Seza İNAL

Author: Süheyla KÖMÜR

Author: Özay AKYILDIZ

Author: Neşe SALTOĞLU

Author: Hasan Salih Zeki AKSU

Author: Yeşim TAŞOVA

Dates

Publication Date: March 1, 2012

Bibtex @ { tbtkmedical147115, journal = {Turkish Journal of Medical Sciences}, issn = {1300-0144}, eissn = {1303-6165}, address = {TUBITAK}, year = {2012}, volume = {42}, pages = {497 - 505}, doi = {}, title = {Clinical appearance of brucellosis in adults: fourteen years of experience}, key = {cite}, author = {KURTARAN, Behice and CANDEVİR, Aslıhan and İNAL, Ayşe Seza and KÖMÜR, Süheyla and AKYILDIZ, Özay and SALTOĞLU, Neşe and AKSU, Hasan Salih Zeki and TAŞOVA, Yeşim} }
APA KURTARAN, B , CANDEVİR, A , İNAL, A , KÖMÜR, S , AKYILDIZ, Ö , SALTOĞLU, N , AKSU, H , TAŞOVA, Y . (2012). Clinical appearance of brucellosis in adults: fourteen years of experience. Turkish Journal of Medical Sciences, 42 (3), 497-505. Retrieved from http://dergipark.org.tr/tbtkmedical/issue/12298/147115
MLA KURTARAN, B , CANDEVİR, A , İNAL, A , KÖMÜR, S , AKYILDIZ, Ö , SALTOĞLU, N , AKSU, H , TAŞOVA, Y . "Clinical appearance of brucellosis in adults: fourteen years of experience". Turkish Journal of Medical Sciences 42 (2012): 497-505 <http://dergipark.org.tr/tbtkmedical/issue/12298/147115>
Chicago KURTARAN, B , CANDEVİR, A , İNAL, A , KÖMÜR, S , AKYILDIZ, Ö , SALTOĞLU, N , AKSU, H , TAŞOVA, Y . "Clinical appearance of brucellosis in adults: fourteen years of experience". Turkish Journal of Medical Sciences 42 (2012): 497-505
RIS TY - JOUR T1 - Clinical appearance of brucellosis in adults: fourteen years of experience AU - Behice KURTARAN , Aslıhan CANDEVİR , Ayşe Seza İNAL , Süheyla KÖMÜR , Özay AKYILDIZ , Neşe SALTOĞLU , Hasan Salih Zeki AKSU , Yeşim TAŞOVA Y1 - 2012 PY - 2012 N1 - DO - T2 - Turkish Journal of Medical Sciences JF - Journal JO - JOR SP - 497 EP - 505 VL - 42 IS - 3 SN - 1300-0144-1303-6165 M3 - UR - Y2 - 2019 ER -
EndNote %0 Turkish Journal of Medical Sciences Clinical appearance of brucellosis in adults: fourteen years of experience %A Behice KURTARAN , Aslıhan CANDEVİR , Ayşe Seza İNAL , Süheyla KÖMÜR , Özay AKYILDIZ , Neşe SALTOĞLU , Hasan Salih Zeki AKSU , Yeşim TAŞOVA %T Clinical appearance of brucellosis in adults: fourteen years of experience %D 2012 %J Turkish Journal of Medical Sciences %P 1300-0144-1303-6165 %V 42 %N 3 %R %U
ISNAD KURTARAN, Behice , CANDEVİR, Aslıhan , İNAL, Ayşe Seza , KÖMÜR, Süheyla , AKYILDIZ, Özay , SALTOĞLU, Neşe , AKSU, Hasan Salih Zeki , TAŞOVA, Yeşim . "Clinical appearance of brucellosis in adults: fourteen years of experience". Turkish Journal of Medical Sciences 42 / 3 (March 2012): 497-505.
AMA KURTARAN B , CANDEVİR A , İNAL A , KÖMÜR S , AKYILDIZ Ö , SALTOĞLU N , AKSU H , TAŞOVA Y . Clinical appearance of brucellosis in adults: fourteen years of experience. Turkish Journal of Medical Sciences. 2012; 42(3): 497-505.
Vancouver KURTARAN B , CANDEVİR A , İNAL A , KÖMÜR S , AKYILDIZ Ö , SALTOĞLU N , AKSU H , TAŞOVA Y . Clinical appearance of brucellosis in adults: fourteen years of experience. Turkish Journal of Medical Sciences. 2012; 42(3): 505-497.