@article{article_1009001, title={Vaginal Smear Test Results of Patients Presenting to Our Pathology Department Between 2011 and 2020 in the Middle Anatolia Region of Turkey}, journal={Eskisehir Medical Journal}, volume={3}, pages={45–52}, year={2022}, DOI={10.48176/esmj.2022.49}, author={İnal, Hasan and Ozturk Inal, Zeynep and Küçükosmanoğlu, İlknur and Eren Karanis, Meryem İlkay}, keywords={rahim ağzı kanseri, insan papilloma virüsü, tarama, vajinal yayma}, abstract={Introduction: The objective of this study is to evaluate the cervical cytology results of patients who presented to the pathology laboratory of our hospital for vaginal smears between 2011 and 2020 according to the Bethesda 2014 classification. <br />Methods: The vaginal smear test reports of 121,537 patients who presented to our pathology laboratory between January 2011 and December 2020 were retrospectively reevaluated. The Bethesda 2014 classification was used for evaluating the results. The data obtained from electronic patient records and the Medical Pathology Department archives were assessed according to the years. <br />Results: The distribution of 121,537 admissions across the years was as follows: 2011: 7915; 2012: 12,211; 2013: 14,912; 2014: 11,907; 2015: 10,170; 2016: 12,234, 2017: 12,756, 2018: 12,846, 2019: 13,124, and 2020: 13,462. All were aged 17-65 years; the mean age was 46.52±11.85 years. Human papillomavirus (HPV) was detected in 3.3% of cases in 2020. The sample adequacy rate was 99.3%. Intraepithelial lesions and malignancy were not detected in 98.5%, the highest rate of inflammation was observed as 11.8%. Squamous cell anomalies constituted 1.3% of epithelial cell anomalies (1.5%). Among the squamous cell anomalies, prevalence of atypical squamous cells of undetermined significance was 0.86%, low-grade squamous intraepithelial lesions was 0.22%, suspected atypical squamous cell was 0.11%, high-grade squamous intraepithelial lesions was 0.08%, and squamous cell carcinoma was 0.01%. Diagnosis of atypical endocervical cells (0.01%) was the most common class of glandular cell anomalies, and endocervical adenocarcinoma (0.003%) was the least common. <br />Conclusion: Cervical smear and HPV DNA tests have an important role in defining cervical intraepithelial lesions. Regional and national screening programs should be used to prevent the transformation of precancerous lesions into invasive cancer. <br />}, number={1}, publisher={Eskişehir Şehir Hastanesi}