TY - JOUR T1 - Covid-19 Hastalarının Tedavisinde Moleküler Hidrojen İnhalasyonunun ‎Potansiyel Uygulaması AU - Alvazeer, Duried AU - Al, Sümeyra AU - Alma, Mehmet Hakkı PY - 2022 DA - June Y2 - 2022 JF - Uluslararası Biyosistem Mühendisliği Dergisi JO - UBSMD PB - Bursa Uludağ Üniversitesi WT - DergiPark SN - 2757-8100 SP - 58 EP - 66 VL - 3 IS - 1 LA - tr AB - COVID-19 (Corona Virüs Hastalığı 2019), SARS-CoV-2 suşunun neden olduğu ciddi ve akut ‎solunum sendromu hastalığıdır. İlk COVID-19 vakası Aralık 2019'da ortaya çıkmış ve aylar ‎içinde tüm dünyada görülen salgın haline gelmiştir. Moleküler hidrojen (H2); reaktif oksijen ‎türlerini seçici olarak süpürmesi, inflamatuar sitokinlerin inaktivasyonu, antiapoptotik ‎özelliği sayesinde birçok hastalık üzerinde etkili bir tedavi yöntemi olarak kullanılmaktadır. ‎Özellikle inflamatuar akciğer yaralanmaları tedavisinde H2’nin terapötik etkileri, COVID-19 ‎hastalığını hafifletebileceği görüşünü desteklemektedir. Aynı zamanda, H2 erken aşamada ‎COVID-19 sırasında SARS-CoV-2'nin neden olduğu yıkıcı sitokin fırtınasını ve akciğer ‎hasarını azaltabilir. Bu nedenle moleküler hidrojen tedavisi, COVID-19 için yeni ve etkili bir ‎tedavi yöntemi olma potansiyeline sahiptir. Fakat bu hipotezin doğrulanması için daha fazla ‎klinik denemelere ihtiyaç vardır.‎ KW - COVID-19 KW - Oksi-Hidrojen KW - Moleküler hidrojen KW - SARS-CoV-2‎ KW - Sitokin fırtınası CR - Alwazeer, D. Potential Cheap and effective Drug for COVID-19 ‎https://www.researchgate.net/post/Potential_Cheap_and_effective_Drug_for_COVID-19 ‎‎(accessed June 26, 2021).‎ CR - Alwazeer, D. and Al, S. (2021). Moleküler Hidrojenin Sağlık Alanında Kullanımı. Karya ‎Journal of Health Science. (Yayın sürecinde)‎ CR - Cabler, S., et al. (2020). "A Cytokine Circus with a Viral Ringleader: SARS-CoV-2-‎Associated Cytokine Storm Syndromes." Trends in Molecular Medicine.‎ CR - Cejka, C., et al. (2020). 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