@article{article_1123440, title={EVALUATION OF THE EFFECTIVENESS OF ALPHA LIPOIC ACID IN THE TREATMENT OF BELL’S PALSY}, journal={The Journal of Kırıkkale University Faculty of Medicine}, volume={24}, pages={397–402}, year={2022}, DOI={10.24938/kutfd.1123440}, author={Taş, Burak Mustafa and Özel, Gökçe and Aras, Müyesser and Kılıç, Rahmi}, keywords={Alfa-lipoik Asit, Elektromyografi, House-Brackmann Derecelendirme Sistemi, Bell paralizi}, abstract={<div style="text-align:justify;"> <b>Objective: </b> This study aims to evaluate the efficacy of alpha-lipoic acid in the treatment of Bell’s palsy by using the House-Brackmann grading system and electromyography. </div> <div style="text-align:justify;"> <b>Material and Methods </b>: A total of 33 patients were included in this retrospective study. Patients were divided into two groups. Group 1 included 18 patients who received 300 mg daily alpha-lipoic acid in addition to Bell’s palsy treatment. Group 2 included 15 patients who only received Bell’s palsy treatment. House-Brackmann grading score at admission, 21st day and at 3rd month were noted in both groups. The results of electromyography performed at 21st day were also scanned. Patients were classified as good prognosis (neuropraxia) and poor prognosis (axonotmesis and neurotmesis) according to electromyography results. The two groups were compared according to House-Brackmann grades and electromyography results. </div> <div style="text-align:justify;"> <b>Results: </b> Group 1 consisted of 10 women and 8 men, while Group 2 consisted of 6 women and 9 men. There was no difference between the two groups according to whether Bell’s palsy was on the right or left side. House-Brackmann grading score of the groups at 21st day and 3rd month were significantly lower than House-Brackmann grading score at admission. There was no significant difference between the two groups according to House-Brackmann grades. There was no difference between the groups in terms of compound muscle action potential ratio and prognosis. </div> <div style="text-align:justify;"> <b>Conclusion: </b>Although alpha-lipoic acid is used for nerve regeneration in various diseases, it did not demonstrate a significant effect on Bell’s palsy treatment in our study. </div>}, number={2}, publisher={Kırıkkale Üniversitesi}