@article{article_1157131, title={Evaluation of platelet-albumin-bilirubin (PALBI) and systemic immune-inflammation (SII) indices in acute intracerebral hemorrhage}, journal={Journal of Medical Topics and Updates}, volume={1}, pages={142–151}, year={2022}, author={Bolayır, Aslı and Bolayır, Hasan Ata and Gökçe, Şeyda Figül and Çiğdem, Burhanettin and Çıplak, Sibel}, keywords={akut intraserebral kanama, platelet-albümin-bilirubin indeksi, sistemik immün-inflamasyon indeksi, inflamasyon, 30 günlük mortalite}, abstract={<div style="text-align:justify;">Background: We aimed to evaluate systemic immune-inflammation (SII) and platelet-albumin-bilirubin indices (PALBI), which are new inflammatory markers, in intracerebral hemorrhage (ICH) patients and reveal the relationship of these values with the disease and their effect on the short-term prognosis of ICH. </div> <div style="text-align:justify;">Materials and Methods: Our retrospective study included 245 patients who were diagnosed with ICH and 250 healthy volunteers. </div> <div style="text-align:justify;">Results: Compared to healthy volunteers, ICH patients had lower PALBI (p=0.028) and higher SII values (p<0.01). Additionlly while SII rate were higher, PALBI rate were lower in patient group with poor prognosis and severe ICH according to mRS (modified Rankin scale) and NIHSS (National Institutes of Health Stroke Scale) both at admission and at the end of 30 days. 45 of 245 patients died within 30 days. Similarly, the SII value in the group who died was statistically significantly higher than the survived group (p<0.01), while PALBI value was lower (p<0.01). Multivariate logistic regression analysis revealed that SII and PALBI values at admission were independent predictors of mortality within 30 days after ICH. Receiver operating characteristic curves showed that 1098.12 for the SII value and -4.11 for the PALBI value were optimal cut-off values to predict 30-day mortality after ICH. </div> <div style="text-align:justify;">Conclusions: The SII and PALBI indices, checked in early period in ICH patients, are closely related to the severity and prognosis of ICH patients both in the acute period and at the end of 30 days. Furthermore, they can be used as independent predictive markers to estimate 30-day mortality after ICH. </div>}, number={3}, publisher={Malatya Turgut Özal Üniversitesi}, organization={Yok}