@article{article_1183793, title={The Known About Familial Mediterranean Fever: Literature Review}, journal={Aksaray University Journal of Sport and Health Researches}, volume={3}, pages={145–155}, year={2022}, DOI={10.54152/asujshr.1183793}, author={Erdal, Huseyin and Eröz, Recep}, keywords={FMF, MEFV, Ailevi Akdeniz Ateşi}, abstract={The most common hereditary autoinflammatory disease is Familial Mediterranean Fever (FMF). Generally, FMF consists of acquiring function mutations of the MEFV gene, which is an auxiliary protein in immune regulation. In recent years, important advances have been seen in the diagnosis of FMF, genetic tests and treatment practices, together with the developing technological developments. In particular, new generation sequencing applications have led to the emergence of clinically important gene variants. Although FMF is clinically seen as a disease characterized by short attacks, studies have shown its relationship with a chronic inflammatory state. In the treatment of FMF, early diagnosis and positive response to treatment are very important in the recovery process of patients. In recent years, research on FMF has been increasing. In this review, it is aimed to evaluate the recent studies on FMF and the findings obtained.}, number={2}, publisher={Aksaray Üniversitesi}