TY - JOUR T1 - The effect of dynamic contrast magnetic resonance imaging (DCE-MRI) in the diagnosis of breast cancer cases TT - Meme kanseri olgularının tanısında dinamik kontrastlı manyetik rezonans görüntüleme (DCE-MRI) yönteminin etkisi AU - Acar, Hasan AU - Akalın, Arkın PY - 2023 DA - April Y2 - 2022 DO - 10.31362/patd.1194142 JF - Pamukkale Medical Journal JO - Pam Med J PB - Pamukkale Üniversitesi WT - DergiPark SN - 1308-0865 SP - 222 EP - 228 VL - 16 IS - 2 LA - en AB - Aim: The aim of this study is to investigate the effect of dynamic contrast magnetic resonance imaging (DCE-MRI) in the diagnosis of breast cancer (BC) and to compare it with ultrasonography (USG).Materials and methods: In our study, 78 patients who underwent preoperative DCE-MRI and USG in our diagnosis center in TRNC between 2009 and 2022 and were diagnosed with BC histopathologically were investigated retrospectively.Findings obtained according to the BI-RADS classification in both methods, detection of BC, detection of tumor foci (TF) in multiple tumors (multicentric and multifocal tumors) (MT), correct diagnosis rates (CDR)s in invasive lobular cancers (ILC) and invasive ductal cancers (IDC) were compared and the results were evaluated statistically.Results: The mean age of the ILC and MT cases was found to be significantly lower than the IDC and unifocal tumor(UF) cases (p<0.05). CDRs in BC cases; 94.8% of DCE-MRI, 78.2% of USG (p<0.05), in the detection of TFs; 94.5% of DCE-MRI, 73.6% of USG (p<0.05), in detecting ILC cases; DCE-MRI 87.5%, USG 37.5% (p>0.05) in detecting IDC cases; it was determined as 95.7% in DCE-MRI and 80.2% in USG (p<0.05).Conclusion: DCE-MRI is a more effective diagnostic method than USG in the diagnosis of BC cases and TFs in MT cases. KW - Magnetic resonance with dynamic contrast KW - breast cancer KW - multiple tumors KW - ultrasonography KW - Dinamik kontrastlı manyetik rezonans KW - meme kanseri KW - multipl tümör KW - ultrasonografi. KW - ultrasonografi N2 - Amaç: Bu çalışmanın amacı meme kanseri (MK) tanısında; dinamik kontrastlı manyetik rezonans görüntülemenin (DCE-MRI) etkisini araştırmak ve ultrasonografi (USG) ile karşılaştırmaktır.Gereç ve yöntem: Çalışmamızda 2009 ve 2022 yılları arasında KKTC deki tanı merkezimizde preoperative olarak DCE-MRI ve USG yapılan ve histopatolojik olarak MK tanısı konulan 78 olgu retrospektif olarak araştırılmıştır.Olgularda her iki yöntemde Bİ-RADS sınıflamasına göre elde edilen bulgular; MK tespiti, multipl tümörlerde (multisentrik ve multifocal tümör) (MT) tümör odaklarının (TO) tespitinde, invaziv lobüler kanserlerde (İLK) ve invaziv duktal kanserlerde (İDK) doğru tanı oranları karşılaştırılmış, sonuçlar istatistiksel olarak değerlendirilmiştir. Bulgular: İLK ve MT olgularının yaş ortalaması, İDK ve tek odaklı tümör (TOT) olgularına göre anlamlı ölçüde küçük bulunmuştur (p<0,05). DTO ları MK olgularında; DCE-MRI’ın %94,8, USG’nin %78,2 (p<0,05), TO larının tespitinde; DCE-MRI’ın %94,5, USG’nin %73,6 (p<0.05), İLK olgularını saptamada; DCE-MRI’ın %87,5, USG’nin %37,5 (p>0,05), İDK olgularını saptamada; DCE-MRI’ın %95,7, USG’nin%80,2 (p<0,05) olarak tespit edilmiştir.Sonuç: DCE-MRI, MK olgularının ve MT olgularında TO’ların tanısında USG’ye göre daha etkili bir tanı yöntemidir. CR - 1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA 2021; 71:209-244. https://doi.org/10.3322/caac.21660 CR - 2. Zubair M, Wang S, Ali N. Advanced Approaches to Breast Cancer Classification and Diagnosis.Front Pharmacol 2021;11:632079. https://doi.org/10.3389/fphar.2020.632079 CR - 3. Acar H, Özer N. Are serum moleculer markers more effective than the invasive methods used in the diagnosis of breast cancers? 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