@article{article_1203106, title={Evaluation of Dynamic Thiol /Disulfide Homeostasis and Ischemia- Modified-Albumin Levels in Cord Blood of Newborns to Patients with Oxytocin-Induced Labor}, journal={Aksaray University Journal of Sport and Health Researches}, volume={3}, pages={193–202}, year={2022}, DOI={10.54152/asujshr.1203106}, author={Erdal, Hüseyin and Bekmezci, Meryem}, keywords={Newborn, Oxidative stress, Ischemia-modified albumin, Thiol-disulfide homeostasis, Oxytocin induction.}, abstract={The aim of this study is to evaluate both dynamic thiol-disulfide and ischemia modified albumin (IMA) levels in cord blood of newborns to patients with oxytocin-induced labor. A total of 30 pregnant women who underwent medical labor induction with oxytocin were compared with 30 women whose labor progressed spontaneously without any kind of induction. The dynamic thiol-disulfide balance was determined by the new colorimetric method developed by Erel et al. IMA levels were analyzed by using albumin cobalt binding test developed by Bar-Or et al. It was found that TAS and OSI levels were higher and TOS levels were lower in the oxytocin-induced group compared to the controls. Native and total thiol levels were found lower while disulfide levels were found higher oxytocin-induced group respect to the control. IMA levels were found significantly different between the patient and control subjects. We indicate that formation of disulfide leads to decrease antioxidant capacity in newborns of oxytocin-induced patients. Dynamic thiol-disulfide homeostasis may contribute to the monitoring of oxidative stress in infants of oxytocin-induced patients and the follow-up of diseases that may arise due to oxidative stress.}, number={2}, publisher={Aksaray Üniversitesi}