TY  - JOUR
T1  - Clinical Significance of CRP/Albumin Value on Hospitalization and Length of Hospital Stay of Patients with Coronavirus-19: A Prospective Study
TT  - CRP/Albumin Değerinin Koronavirüs-19 Hastalarının Hastanede Yatış Süresi ve Hastanede Kalış Süresi Üzerindeki Klinik Önemi: Prospektif Çalışma Çalışma
AU  - Lök, Uğur
AU  - Gülaçtı, Umut
AU  - Kafadar, Hüseyin
AU  - Kaya, Hakan
PY  - 2023
DA  - July
Y2  - 2023
DO  - 10.17517/ksutfd.1222637
JF  - Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi
JO  - KSU Medical Journal
PB  - Kahramanmaraş Sütçü İmam Üniversitesi
WT  - DergiPark
SN  - 1303-6610
SP  - 99
EP  - 105
VL  - 18
IS  - 2
LA  - en
AB  - Objective: To investigate the diagnostic and prognostic significance of the C-reactive protein-to-albumin ratio (CAR) in coronavirus disease 2019 (COVID-19) patients admitted for the first time to a hospital emergency department (ED).Materials and methods: The study we report herein was a single-center, prospective observational study. A total of 745 participants (385 patients, 360individuals) were included in the study. The CAR was calculated by dividing the C-reactive protein (CRP; mg/L) value by the albumin value (gr). The datawere analyzed using MedCalc Statistical Software v12.7.0.0 (Ostend, Belgium) and Student’s t-test, chi square test, and Pearson’s correlation coefficient. Ap-value of <0.05was considered statistically significant.Results: A total of 355 patients were hospitalized, and 30 of them were followed as outpatients. The mean CAR values of the hospitalized patients and theoutpatients were 0.34±0.89 and 0.39±0.72 respectively (95% confidence interval [CI]: -0.31 to 0.40; p=0.796). A 309 patients were hospitalized in wardsand 46, in intensive care units; their mean CAR values were 0.33±0.92 and 0.44±0.74, respectively (95% CI: -0.17 to 0.39; p=0.449). As the CAR value increased,the length of hospital stay also increased (p<0.0001). At the best cut-off point for COVID-19 diagnosis, CAR was shown to have 82.66% specificity,69.72% sensitivity, 4.02 positive likelihood, and 0.37 negative likelihood.Conclusion: The length of stay in the hospital of the COVID-19 patients in the study was closely related to their CAR values obtained at the time of theirfirst ED admission.s closely related to their CAR values obtained at the time of their first ED admission.
KW  - Coronavirus disease 2019
KW  - C reactive protein to albumin ratio
KW  - first admission
KW  - hospital stay
N2  - Amaç: İlk tanısı acil servis te yapılan Koronavirüs 2019 (COVID-19) hastalarda C- reaktif protein/albümin oranının (CAR) tanısal ve prognostik öneminiaraştırması.Gereç ve Yöntemler: Burada sunduğumuz çalışma, tek merkezli, ileriye dönük gözlemsel bir çalışmadır. Çalışmaya toplam 745 katılımcı (385 hasta,360 kişi) dâhil edildi. CAR, C-reaktif protein (CRP; mg/L) değerinin albümin değerine (gr) bölünmesiyle hesaplandı. Veriler MedCalc İstatistik Yazılımıv12.7.0.0 (Oostende, Belçika) ve Student t testi, ki kare testi ve Pearson korelasyon katsayısı kullanılarak analiz edildi. p<0.05 değeri istatistiksel olarakanlamlı kabul edildi.Bulgular: Toplam 355 hasta yatarak tedavi edildi ve bunların 30’u ayaktan takip edildi. Hastanede yatan hastaların ve ayaktan hastaların ortalama CARdeğerleri sırasıyla 0.34±0.89 ve 0.39±0.72 idi (%95 güven aralığı [GA]: -0.31 ila 0.40; p = 0.796). 309 hasta koğuşlarda, 46 hasta ise yoğun bakım ünitelerindetedavi edilirken; ortalama CAR değerleri sırasıyla 0.33±0.92 ve 0.44±0.74 idi (%95 GA: -0.17 ila 0.39; p=0.449). CAR değeri arttıkça hastanede kalışsüresi de arttı (p< 0,0001). COVID-19 teşhisi için en iyi kesme noktasında CAR’ın %82.66 özgüllük, %69.72 duyarlılık, 4.02 pozitif olasılık ve 0.37 negatifolasılığa sahip olduğu gösterildi.Sonuç: Çalışmadaki COVID-19 hastalarının hastanede kalış süresi, ilk acil servise başvuru anında tespit edilen CAR değerleri ile yakından ilişkiliydi.rının hastanede kalış süresi, ilk acil servise başvuru anında tespit edilen CAR değerleri ile yakından ilişkiliydi.
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UR  - https://doi.org/10.17517/ksutfd.1222637
L1  - http://dergipark.org.tr/tr/download/article-file/2846221
ER  -