TY - JOUR T1 - İnsülin kullanan tip 2 diabetes mellitus hastalarında mikrovasküler komplikasyonlar ile depresyonun ilişkisi TT - The relationship between microvascular complications and depression in patients with type 2 diabetes mellitus who use insulin AU - Eren, Mehmet Ali AU - Torun, Ayşe Nur AU - Tabur, Suzan AU - İngeç, Muharrem AU - Demir, Mehmet AU - Sabuncu, Tevfik AU - Karababa, İbrahim Fatih PY - 2013 DA - March DO - 10.5799/ahinjs.01.2013.01.0230 JF - Journal of Clinical and Experimental Investigations JO - J Clin Exp Invest PB - Aydın ECE WT - DergiPark SN - 1309-8578 SP - 34 EP - 39 VL - 4 IS - 1 LA - tr AB - Amaç: Bu çalışmada kronik bir hastalık olan Tip 2 Dia­betes Mellitus (DM) ve komplikasyonlarının depresyon şiddeti ile ilişkisi değerlendirilmesi amaçlandı. Yöntemler: Çalışmaya 65 yaşından küçük, insülin kullan­makta olan 80 Tip 2 DM hastası alınarak klinik ve biyokim­yasal verileri kaydedildi. Nöropati şiddeti “United Kingdom nöropati tarama skoru” (UKNS) ile, depresyon şiddeti ise “Beck Depresyon Envanteri” (BDE) ile belirlendi. Nefro­pati spot idrar örneğinde mikroalbumin-kreatinin oranı ile, retinopati ise göz dibi muayenesi ile değerlendirildi. Bulgular: Beck depresyon şiddeti yüksek olan hasta gru­bu içindeki nöropati şiddeti yüksek olan hasta sayısı daha fazlaydı (p KW - Tip 2 Diabetes Mellitus KW - nöropati KW - nefropati KW - retinopati KW - depresyon N2 - Objective: This study aimed to assess the relationship between Type 2 Diabetes Mellitus (DM) and its complica­tions with the severity of depression. Methods: Eighty diabetics under the age of 65 using insulin were enrolled and clinical and biochemical data were recorded. The severity of neuropathy was deter­mined by the “United Kingdom neuropathy screening score” (UKNS) whereas the severity of depression was determined by the “Beck depression scale” (BDS). Ne­phropathy and retinopathy were assessed by the micro­albumin-creatinine ratio in spot urine samples and by de­tailed examination of the retina with an ophthalmoscope, respectively. Results: There were more patients who has high neurop­athy severity in the group with the highest Beck depres­sion scale score (p CR - Schellhase KG, Koepsell TD, Weiss NS. Glycemic control and the risk of multiple microvascular diabetic complications. Fam Med 2005;37:125-130. CR - Ma J, Yang W, Fang N, et al. The association between intensive glycemic control and vascular complica- tions in type 2 diabetes mellitus: a meta-analysis. Nutr Metab Cardiovasc Dis 2009;19:596-603. CR - Carney C. Diabetes mellitus and major depressive dis- order: an overview of prevalence, complications, and treatment. Depress Anxiety 1998;7:149–157. CR - Anderson RJ, Freedland KE, Clouse RE, et al. The prevalence of comorbid depression in adults with dia- betes: a meta-analysis. 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