TY - JOUR T1 - Solifenazin\'e bağlı diskinezi TT - Solifenacin induced dyskinesia AU - Dağ, Ersel AU - Azapoğlu, Burcu AU - Deniz, Turgut PY - 2012 DA - December DO - 10.5799/ahinjs.01.2012.04.0218 JF - Journal of Clinical and Experimental Investigations JO - J Clin Exp Invest PB - Aydın ECE WT - DergiPark SN - 1309-8578 VL - 3 IS - 4 LA - tr AB - Aşırı aktif mesane inkontinans olsun ya da olmasın urgency ile ilişkili kronik bir durumdur. Solifenazin günde tek doz kullanılan selektif antimuskarinik bir ajandır. Günde 5 mg olarak başlanır, tolere edilebilirse 10 mg\'a artırılabilir. Biz burada solifenazin kullanımı sonrası ortaya çıkan ve ilacın kesilmesini takiben birkaç gün içinde ortadan kaybolan diskinezili bir olguyu sunduk. KW - Aşırı aktif mesane KW - solifenazin KW - diskinezi. N2 - Overactive bladder syndrome is a chronic condition characterised by urgency, with or without associated urge incontinence. Solifenacin succinate is a once daily, bladder selective antimuscarinic available. The recommended dose is 5 mg once daily and can be increased to 10 mg once daily if 5 mg is well tolerated. We report here a case with dyskinesia emerged following the use of solifenacin, and disappeared in a few days with stopping the agent. CR - Wagg A, Wyndaele JJ, Sieber P. Efficacy and toler- ability of solifenacin in elderly subjects with overactive bladder syndrome: a pooled analysis. Am J Geriatr Pharmacother 2006;4(1):14-24. CR - Chancellor MB, Zinner N, Whitmore K, et al. Efficacy of solifenacin in patients previously treated with tolt- erodine extended release 4 mg: results of a 12-week, multicenter, open-label, flexible-dose study. Clin Ther 2008;30(10):1766-81. CR - Basra R, Kelleher C. A review of solifenacin in the treat- ment of urinary incontinence. Ther Clin Risk Manag. 2008;4(1):117-28. CR - Cardozo L, Lisec M, Millard R, et al. Randomized, double-blind placebo controlled trial of the once daily antimuscarinic agent solifenacin succinate in patients with overactive bladder. J Urol 2004;172(5):1919-24. CR - Suzuki M, Noguchi Y, Okutsu H, Ohtake A, Sasamata M. Effect of antimuscarinic drugs used for overactive bladder on learning in a rat passive avoidance re- sponse test. Eur J Pharmacol 2007;557(2-3):154-8. CR - Piecoro LT, Wermeling DP, Schmitt FA, Ashford JW. Seizures in patients receiving concomitant antimus- carinics and acetylcholinesterase inhibitor. Pharma- cotherapy 1998;18(5):1129-32. UR - https://doi.org/10.5799/ahinjs.01.2012.04.0218 L1 - http://dergipark.org.tr/tr/download/article-file/104212 ER -