TY - JOUR TT - Paraneoplastic digital necrosis associated with rectum carcinoma AU - Alkan, Ali AU - Özgül, Seçkin AU - Yaşar, Arzu AU - Karcı, Ebru AU - Köksoy, Elif AU - Utkan, Güngör PY - 2016 DA - January DO - 10.5799/ahinjs.01.2015.04.0555 JF - Journal of Clinical and Experimental Investigations JO - J Clin Exp Invest PB - Aydın ECE WT - DergiPark SN - 1309-8578 VL - 6 IS - 4 LA - tr AB - Paraneoplastik vasküler patolojiler günlük pratikte nadirdir ve bu konuda bilgi sınırlıdır. Burada rektum kanseri ilişkili paraneoplastik dijital nekroz vakası sunulmuştur. Metastatik rektum kanseri ile izlenmekte olan hasta dijital nekroz ile başvurdu. Yapılan değerlendirmede vasküler veya romatolojik hastalığa ait bulgu saptanmadı. Lezyonlar steroid tedavisi ile geriledi. Onkoloji pratiğinde paraneoplastik vasküler lezyonlar oldukça nadirdi. Vakamız bu nadir patolojinin klinik özellikleri, tanısı ve tedavisine dikkat çekmektedir KW - Rektum kanseri KW - dijital nekroz KW - paraneoplastik sendrom N2 - Paraneoplastic vascular pathologies are rare in daily practice. There is limited data about this phenomenon. Patient with a diagnosis of metastatic rectum carcinoma presented with digital necrosis. The work up for vascular and rheumatological pathology was inconclusive. Lesions progressively improved with steroid therapy. Paraneoplastic vascular lesions are rare in oncology practice. Our case points out important parts of a rare clinical entity.J Clin Exp Invest 2015; 6 (4): 391-392Key words:Rectum cancer, digital necrosis, paraneoplastic CR - 1. Taylor L, Hauty MG, Edwards JM, Porter JM. Digital ischemia as a manifestation of malignancy. Ann Surg 1987;206:62-68. CR - 2. Wright JR, Gudelis S. Digital necrosis associated with squamous cell carcinoma of the tonsil: Head & Neck 2002;24:1019-1021. CR - 3. Petri M, Fye KH. Digital necrosis: a paraneoplastic syndrome. J Rheumatol 1985;12:800-802. CR - 4. Radic M, Kaliterna DM, Radic J. Drug-induced vasculitis: a clinical and pathological review. Neth J Med 2012;70:12-17. CR - 5. Hill SE, Phillips R, Francis N, Agnew K. Small-vessel vasculitis following treatment with combination 5-fluorouracil/folinic acid and oxaliplatin. Clin Exp Dermatol 2009;34:103-105. CR - 6. Pellegrini F, Astorino S, Castaldi N, et al. Small vessel vasculitis related to 5-fluorouracil and folinic acid. Eur J Dermatol 2010;20:862-863. UR - https://doi.org/10.5799/ahinjs.01.2015.04.0555 L1 - http://dergipark.org.tr/tr/download/article-file/104550 ER -