TY - JOUR T1 - Evaluation of Botulinum Toxin Applications in a Tertiary Cosmetic Department TT - Bir Eğitim Araştırma Hastanesinde Kozmetik Amaçlı Botulinum Toksin Uygulamalarının Değerlendirilmesi AU - Örenay, Özge Mine AU - Temel, Berkay AU - Karaosmanoğlu, Nermin PY - 2024 DA - January DO - 10.20492/aeahtd.1278151 JF - Ankara Eğitim ve Araştırma Hastanesi Tıp Dergisi PB - Sağlık Bakanlığı Ankara Eğitim ve Araştırma Hastanesi WT - DergiPark SN - 1304-6187 SP - 156 EP - 159 VL - 56 IS - 3 LA - en AB - Aim: Botulinum toxin type A (BTX-A) treatment for facial rejuvenation hasbeen started to used widely and become the most common aesthetic procedure. The aim inthis study to evaluate the patients features and outcomes who had Onabotulinumtoxin A.Material and Method: The data of the BTX-A patient’s gender, age, occupation, history of cosmeticprocedures, history of disease, doses of the first and control injections, complications andexpectations from the therapy collected from the medical records. The patients were dividedinto two groups as under the age of 45 and age of 45 and older. These groups were comparedwith each other in terms of mentioned variables.Results: A total of 200 patients included in this study. The mean botulinum toxin dose was33.7 units and the mean control dose was 4.5 units. Three (1.5%) of the patients developed acomplication, all of them were eyelid ptosis. Most common expectation from the toxininjection was to look more young (69%) and vigorous (75.5%). There were no significantdifference between the under the age of 45 and 45 and older group in terms of total BTX-Adose and control dose and complication rate (p=0.8, p=0.5, p=0.6). Expectation of lookingless angry and less saggy were significantly higher in the 45 year and older group (p=0.02,p=0.02).Conclusion: It is important to evaluate the patient’s gender, age and expectations from thebotulinum toxin injection to get the highest efficiency from BTX-A injection. KW - botox KW - wrinkles KW - face rejunevation N2 - GİRİŞ-AMAÇ: Botulinum toksini, Gram negatif bir bakteri olan Clostridium botulinum tarafından sentezlenenbir nörotoksindir. Kozmetik amaçlı ilk kez 1992 yılında glabella kırışıklıkları tedavisinde kullanılmıştır. Fasiyalkırışıklık tedavisinde giderek artan sıklıklarla uygulanmaya başlanmıştır. Bu çalışmada, eğitim araştırmahastanesinde kozmetik amaçlı uygulanan botulinum toksin uygulamalarının değerlendirilmesini amaçladık.YÖNTEM: Çalışmaya, 2018-2019 yıllarında hastanemizin kozmetoloji ünitesine kozmetik amaçlı botulinumtoksin uygulaması için başvurmuş 200 hasta dahil edilmiştir. Hastaların dosyaları taranarak; demografikbulguları, kozmetik işlem geçmişleri, uygulanan botoks dozları, kontrol dozu uygulamaları, komplikasyonlar vebotokstan beklentileri kaydedildi. Ayrıca hastalar 45 yaş altı ve 45 yaş ve üstü olarak iki gruba ayrılarak, ikigrubun kozmetik işlem geçmişleri, uygulanan botoks dozları, kontrol dozu uygulamaları, komplikasyonlar vebotokstan beklentileri karşılaştırılmıştır.BULGULAR: Çalışmaya dahil edilen 200 hastanın 195’i kadın (%97,5) ve 5’i erkek (%2,5) hastaydı. Hastalarınyaş ortalaması 44,8 idi. Daha önce hastaların 107’si (%53,5) botoks yaptırmış, 40’ı (%20) ise dolgu işlemiyaptırmıştır. Hastaların hepsine üst yüz botoksu uygulanırken, alt yüz botoksu 55 (%27,5) hastaya uygulandı.Hastalara uygulanan total botoks dozu 33,7 Ü idi. Hastaların 131’ine (%65,5) kontrol doz uygulandı. Uygulanankontrol doz ortalaması 4,5 Ü idi. Hastaların 3’ünde (%1,5) komplikasyon olarak pitozis gözlendi. Hastalar dinçgörünme, mutlu görünme, çekici görünme, zarif görünme, feminen görünme, genç görünme, az öfkeli görünmeve az sarkık görünme seçenekleri arasından, en çok dinç görünmek için botoks yaptırdığını belirtmiştir. Kırkbeşyaş altı hasta grubunda 101 kadın ve 3 erkek (total:104), 45 yaş ve üstü grubunda 94 kadın ve 2 erkek (total:96)vardı. Hastalar 45 yaş altı ve 45 yaş ve üstü olarak karşılaştırıldığında; botoks ve dolgu geçmişi, alt yüz botoksişlemi, total ve kontrol doz ortalaması, komplikasyon gelişimi açısından istatiksel olarak anlamlı farksaptanmamıştır. Hastaların botoks işleminden beklentisine bakıldığında ise 45 yaş ve üstü grubun, 45 yaş altıgruba göre daha az öfkeli ve daha az sarkık görünme isteği anlamlı yüksek bulunmuştur (p=0,018, p=0,029).SONUÇ: Botoks tedavisi hastaların farklı amaçlarla başvurduğu, kişi bazlı değerlendirme gerektiren etkili vekomplikasyon oranı düşük bir tedavi yöntemidir. CR - 1.Jia Z, Lu H, Yang X, Jin X, Wu R, Zhao J, et al. Adverse Events of Botulinum Toxin Type A in Facial Rejuvenation: A Systematic Review and Meta-Analysis. Aesthetic Plast Surg. 2016;40(5):769-77. CR - 2.Charles FJ, Cox SE, Earl ML. Social implications of hyperfunctional facial lines. Dermatol Surg. 2003;29(5):450-5. CR - 3.Gart MS, Gutowski KA. Overview of Botulinum Toxins for Aesthetic Uses. Clin Plast Surg. 2016;43(3):459-71. 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