TY - JOUR T1 - Changes in structure during the corpus luteum's formation TT - Korpus luteum oluşumu sırasında meydana gelen yapısal değişiklikler AU - Seçme, Mücahit AU - Ünal, Murat Serkant AU - Tan, Semih PY - 2024 DA - April Y2 - 2024 DO - 10.31362/patd.1383988 JF - Pamukkale Medical Journal JO - Pam Tıp Derg PB - Pamukkale Üniversitesi WT - DergiPark SN - 1308-0865 SP - 285 EP - 301 VL - 17 IS - 2 LA - en AB - Purpose: Our study aims to investigate whether new follicles form among fibroblast-like cells in the region after the restructuring of the surface epithelium and tunica albuginea adjacent to the corpus luteum. Additionally, another goal is to demonstrate the structures developed from the follicles and the histological changes in the ovary.Materials and methods: Histological sections of the corpus luteum, formed from the Graafian follicle after ovulation, were prepared from ovarian tissues of 12-14 months old Wistar albino rats.Results: When the corpus luteum reaches a high volume, the number of fibroblast-like cells in the tunica albuginea is quite low. Subsequently, it has been observed that the number of fibroblast-like cells in the tunica albuginea rapidly increases, and these cells form concentric arrangements of collagen fibers. Additionally, the formation of primordial and primary follicles between the surface epithelium and the tunica albuginea adjacent to the corpus luteum has been observed.Conclusion: Examining the ovary as a whole and investigating the developmental processes of structures can assist in gaining a better understanding of the dynamics of this organ. KW - Corpus Luteum KW - ovary KW - tunica albuginea KW - follicles N2 - Amaç: Çalışmamız, korpus luteum'un bitişiğindeki yüzey epiteli ve tunika albugineanın yeniden yapılanmasından sonra bu bölgedeki fibroblast benzeri hücrelerin arasında yeni foliküllerin oluşup oluşmadığını araştırmayı amaçlamaktadır. Ayrıca, foliküllerden gelişen yapıları ve ovaryumdaki histolojik değişiklikleri göstermek de bir başka hedefimizdir.Gereç ve yöntem: Ovulasyondan sonra graaf folikülünden oluşan korpus luteum'un histolojik kesitleri, 12-14 aylık Wistar albino tipi sıçanların ovaryum dokularından alınarak hazırlanmıştır.Bulgular: Korpus luteum yüksek bir hacime ulaştığında, tunika albugineada bulunan fibroblast benzeri hücrelerin sayısı oldukça düşüktür. Daha sonrasında, tunika albuginea bulunan fibroblast benzeri hücrelerin sayısının hızla arttığı ve bu hücrelerin oluşturduğu kollajen liflerin konsantrik dizilim oluşturdukları gözlemlenmiştir. 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J Ovarian Res 2015;8:70. https://doi.org/10.1186/s13048-015-0200-0 UR - https://doi.org/10.31362/patd.1383988 L1 - https://dergipark.org.tr/tr/download/article-file/3507949 ER -