TY - JOUR T1 - Epididymo-Orchitis Caused by Hand, Foot, and Mouth Disease In Adults AU - Gültekin, Arif Cengiz PY - 2024 DA - September Y2 - 2024 DO - 10.58854/jicm.1389854 JF - Journal of Immunology and Clinical Microbiology JO - J Immunol Clin Microbiol PB - Erkan YULA WT - DergiPark SN - 2528-9470 SP - 97 EP - 100 VL - 9 IS - 3 LA - en AB - Hand, Foot, and Mouth Disease (HFMD) is predominantly recognized as a childhood disease and is not generally anticipated to manifest in adults. In addition to inducing symptoms such as fever, herpangina, and distal-extremity rashes, HFMD can also lead to rare complications such as encephalitis and onychomadesis. Epididymo-orchitis, however, is not considered an expected complication of HFMD.In our case, a patient diagnosed with HFMD presented with testicular pain four days later, and epididymo-orchitis was subsequently identified in the patient initially suspected of testicular torsion. Cases of Coxsackie virus-related epididymo-orchitis have been reported in the literature, and these cases can be mistaken for torsion, thereby posing the risk of unnecessary surgical interventions. Testicular pain in a young adult with a history of HFMD should be considered a potential diagnosis of viral epididymo-orchitis. KW - Hand KW - Footh KW - and Mouth Disease KW - Epididymo-Orchitis KW - Coxasckie virus N2 - El, Ayak ve Ağız Hastalığı (HFMD), ağırlıklı olarak çocukluk çağı hastalığı olarak kabul edilmektedir ve genellikle yetişkinlerde ortaya çıkması beklenmemektedir. HFMD, ateş, herpanjina ve distal ekstremite döküntüleri gibi semptomları tetiklemenin yanı sıra ensefalit ve onikomadezis gibi nadir komplikasyonlara da yol açabilir. Ancak epididimo-orşit, HFMD’nin beklenen bir komplikasyonu olarak görülmemektedir.Bu olguda HFMD tanısı alan bir hasta dört gün sonra testis ağrısı şikayetiyle başvurmuş ve testis torsiyonundan şüphelenilen hastada daha sonra epididimo-orşit tespit edilmiştir. Literatürde Coxsackie virüsüne bağlı epididimo-orşit vakaları bildirilmiş olup, bu vakalar torsiyon ile karıştırılarak gereksiz cerrahi girişim riski oluşturabilir. HFMD öyküsü olan genç bir yetişkinde testis ağrısı, potansiyel bir viral epididimo-orşit tanısı olarak düşünülmelidir. CR - Ventarola D, Bordone L, Silverberg N. Update on hand-foot-and-mouth disease. Clin Dermatol. 2015;33(3):340-346. CR - Yüksel S, et al. Onychomadesis—a late complication of hand-foot-mouth disease. J Pediatr. 2016;174:274. CR - Shah J, et al. Neurological complications of hand, foot and mouth disease in children: a review. J Ayub Med Coll Abbotta-bad. 2020;32(4):562-569. CR - Holmes K, Berger R, Alexander E. Acute epididymitis: etiology and therapy. Arch Androl. 1979;3(4):309-316. CR - Liu W, et al. Viral threat to male fertility. Andrologia. 2018;50(11). CR - Ludwig M. Diagnosis and therapy of acute prostatitis, epididymitis and orchitis. Andrologia. 2008;40(2):76-80. CR - Vuorinen T, et al. Epididymitis caused by coxsackievirus A6 in association with hand, foot, and mouth disease. J Clin Mic-robiol. 2014;52(12):4412-4413. CR - Di Lella E, et al. An unusual location of hand, foot and mouth disease. J Ultrasound. 2021;24(1):1-4 UR - https://doi.org/10.58854/jicm.1389854 L1 - http://dergipark.org.tr/tr/download/article-file/3533163 ER -