TY - JOUR T1 - Impact of Vaccines on Mortality in Patients Treated in The Intensive Care Unit Due To COVID-19: A Multicenter Study AU - Gürbüz, Hüseyin AU - Balkan, Yasemin AU - Mete, Ayşe Özlem AU - Uyan, Berna AU - Koçak, Kübra AU - Cansunar, Selim Bülent AU - Ugurlu, Kenan AU - Karaoglan, İlkay PY - 2023 DA - December DO - 10.5798/dicletip.1411963 JF - Dicle Medical Journal JO - diclemedj PB - Dicle Üniversitesi WT - DergiPark SN - 1300-2945 SP - 529 EP - 536 VL - 50 IS - 4 LA - en AB - Introduction: The importance of vaccines is increasing day by day because the COVID-19 pandemic has been going on for about two years and there is no effective antiviral treatment. The purpose of this study was to compare the impact of vaccination status on the mortality of patients monitored in the intensive care unit with the diagnosis of COVID-19.Methods: Three hundred and forty-four patients treated in intensive care due to COVID-19 in three hospitals in Gaziantep were included in the study. Demographic characteristics and pre-COVID-19 vaccination status of all patients were recorded, and the diagnosis of COVID-19 was made with nasopharyngeal polymerase chain reaction (PCR) test and Thorax Computed Tomography (CT).Results: Of the patients, 172 (50%) were male, 172 (50%) were female, 152 (44%) were unvaccinated and 192 (55%) were vaccinated. The number of male patients (n=106) (55.2%) in the vaccinated group was significantly higher than female patients (n=86) (44.8%) (p KW - Covid-19 vaccines KW - Intensive Care Unit KW - Efficacy KW - Mortality CR - 1.Cheng H, Peng Z, Luo W, et al. Efficacy and safetyof COVID-19 vaccines in phase III trials: a meta-analysis. Vaccines. 2021; 9; 1-14. CR - 2.https://www.titck.gov.tr/haber/1423 CR - 3. https://www.trthaber.com/haber/gundem/BioNTech-asisi¬uygulanmaya-baslandi-569556.html CR - 4.https://covid-19asi.saglik.gov.tr/ CR - 5.https://covid-19.saglik.gov.tr/ CR - 6.Vicini S, Panvini N, Bellini D, et al. Radiographersand COVID-19 pneumonia: Diagnostic performanceusing CO-RADS. Radiography. 2021; 27; 1078-84. CR - 7. Whittaker R, Kristofferson AB, Salamanca BV, et al. Length of hospital stay and risk of intensive careadmission and in-hospital death among COVID-19patients in Norway: a register-based cohort studycomparing patients fully vaccinated with an mRNAvaccine to unvaccinated patients. ClinicalMicrobiology and Infection. 2022; 28; 871-8. CR - 8.Sevinc SA, Metin S, Basi N, et al. Effectiveness ofinactivated SARS-CoV-2 vaccine (CoronaVac) onintensive care unit survival. Epidemiology &Infection. 2022; 150; e35. CR - 9.Whittaker R, Kristofferson AB, Salamanca B V, etal. Length of hospital stay and risk of intensive careadmission and in-hospital death among COVID-19 patients in Norway: a register-based cohort study comparing patients fully vaccinated with an mRNA vaccine to unvaccinated patients. Clinical Microbiology and Infection. 2022; 28; 871-8. CR - 10.Starrfelt J, Danielsen AS, Buanes E, et al. Age andproduct dependent vaccine effectiveness againstSARS-CoV-2 infection and hospitalisation amongadults in Norway: a national cohort study, July–November 2021. BMC medicine. 2022; 20; 1-11. CR - 11.Lim WS, Liang CK, Assantachai P, et al. COVID-19and older people in Asia: Asian Working Group forSarcopenia calls to actions. Geriatrics & gerontologyinternational. 2020; 20; 547–58. CR - 12.Niu S, Tian S, Lou J, et al. Clinical characteristicsof older patients infected with COVID-19: Adescriptive study. Archives of gerontology andgeriatrics. 2020; 89; 104058. CR - 13.Tenforde MW, Self WH, Adams K, et al.Association between mRNA vaccination and COVID-19 hospitalization and disease severity. Jama. 2021;326; 2043-54. CR - 14.Bahl A, Johnson S, Maine G, et al. Vaccinationreduces need for emergency care in breakthroughCOVID-19 infections: A multicenter cohort study.The Lancet Regional Health-Americas2021; 4;100065. CR - 15.Rotshild V, Hirsh-Raccah B, Miskin I, et al.Comparing the clinical efficacy of COVID-19vaccines: a systematic review and network meta-analysis. Scientific reports. 2021; 11; 22777. CR - 16.Tregoning JS, Flight KE, Higham SL, et al.Progress of the COVID-19 vaccine effort: viruses,vaccines and variants versus efficacy, effectivenessand escape. Nature reviews immunology.2021; 21;626-36. CR - 17.Koc F, Göktas EF, Firat P, et al. Risk factors forintensive care unit need in patients with COVID-19:An analysis of 368 cases. Dicle Tıp Dergisi. 2022; 49;287-96. CR - 18.Cheng H, Peng Z, Luo W, et al. Efficacy and safetyof COVID-19 vaccines in phase III trials: a meta-analysis. Vaccines. 20221; 9; 582. UR - https://doi.org/10.5798/dicletip.1411963 L1 - http://dergipark.org.tr/tr/download/article-file/3629063 ER -