TY - JOUR T1 - SARS-CoV-2 COVID-19 Enfeksiyonunun Gebelik ve Fetus Üzerine Etkileri TT - Maternal and Fetal Effects of SARS-CoV-2 COVID-19 AU - Dursun, Polat PY - 2020 DA - September JF - Yüksek İhtisas Üniversitesi Sağlık Bilimleri Dergisi JO - YIU Saglik Bil Derg PB - Yüksek İhtisas Üniversitesi WT - DergiPark SN - 2717-8439 SP - 73 EP - 77 VL - 1 IS - 2 LA - tr AB - SARS-CoV-2 virüsünün yol açtığı COVID-19 enfeksiyonu üst ve alt solunum yollarını enfekte ederek hafiften çok ağıra doğru akut solunum yetmezliği ile karakterize bir viral pnömoni tablosu oluşturmaktadır. Gebelikte COVID-19 enfeksiyonun seyri ve komplikasyonları halen net bilinmemektedir. Bu makalede COVID-19 enfeksiyonunun gebelerdeki seyri ve yeni doğanlardaki etkisi özetlenmiştir. KW - SARS-CoV-2 KW - COVID-19 KW - gebelik KW - fetus KW - yenidoğan N2 - SARS-CoV-2 is a RNA virus is also known as COVID-19. COVID-19 causes a viral pneumonia which affect upper and lower respiratory tract. However, the effect of COVID-19 on pregnancy and the fetus is still a dilemma for clinicans and scientist. In this review article, the effect of COVID-19 on both pregnant women and newborn was summarized. CR - https://www.who.int/emergencies/diseases/novel-coronavirus-2019?gclid=EAI aIQobChMIr9Og7I2C6gIVh7PtCh2s4QTSEAAYASAAEgLX7PD_BwE CR - https://covid19bilgi.saglik.gov.tr/tr/ CR - Liu H , Zhao LWS , Kwak-Kim J , Mor M , Liao AH. Why Are Pregnant Women Susceptible to COVID-19? An Immunological Viewpoint. J Reprod Immunol. 2020 Jun;139:103122. doi: 10.1016/j.jri.2020.103122 CR - Aghaeepour N .An immune clockof human pregnancy. Sci.Immunol.2 15 . 2017;https://doi.org/10.1126/sciimmunol.aan2946. CR - Wong S.F.Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. A m.J.Obstet.Gynecol.191,292–297.https://doi.org/10. 1016/j.ajog.2003.11.019. CR - Mor G.The unique immunological and microbial aspects of pregnancy.Nat.Rev. Immunol.17,4 CR - Choi,G.B .The maternal interleukin-17 a pathway in mice promotes autism like phenotypes in offspring.Science 2016;351,933–939.https://doi.org/10.1126/ science.aad0314 CR - Yockey LJ, Iwasaki,A. Interferons and proinflammatory cytokines in pregnancy and fetal development.Immunity 201849,397–412.https://doi.org/10.1016/j. immuni. 2018.07.017 CR - Werenberg DJ..Fever and infections in pregnancy and risk of attention deficit/ hyperactivity disorder in the offspring. J.ChildPsychol.Psychiatry 2016;57, 540–548.https://doi.org/10.1111/jcpp.12480. CR - Mullins E, Evans D, Viner RM, O’Brien P, Morris E. Coronavirus in pregnancy and delivery: rapid review.Ultrasound Obstet Gynecol. 2020 ;55:586-592. doi: 10.1002/uog.2201 CR - Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies .Acta Obstet Gynecol Scand. 2020 Apr 7:10.1111/aogs.13867. doi: 10.1111/aogs.13867. Online ahead of print. CR - Zhu H, Wang L, Fang C. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020;9:51-60. CR - Wang S, Guo L, Chen L. A case report of neonatal COVID 19 infection in China. Clin Infect Dis. 2020. pii: ciaa225. [Epub ahead of print] CR - Liu Y, Chen H, Tang K, Guo Y. Clinical manifestations and outcome of SARS- CoV-2 infection during pregnancy. J Infect. 2020. CR - Breslin N, Baptiste C, Miller R. COVID-19 in pregnancy: early lessons. Am J Obstet Gynecol MFM. 2020 CR - Zeng H, Xu C, Fan J. Antibodies in infants born to mothers with COVID-19 pneumonia. JAMA. 2020. doi: 10.1001/jama.2020.4861 [Epub ahead of print]. CR - Dong L, Tian J, He S. Possible vertical transmission of SARSCoV-2 from an infected mother to her newborn. JAMA. 2020. doi: 10.1001/jama.2020.4621. [Epub ahead of print] CR - Wong SF, Chow KM, Leung TN. Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome. Am J Obstet Gynecol. 2004;191:292- 297. CR - Alfaraj SH, Al-Tawfiq JA, Memish ZA. Middle East respiratory syndrome coronavirus MERS-CoV infection during pregnancy: report of two cases and review of the literature. J Microbiol Immunol Infect. 2019;52:501-503 CR - Di Mascio D, Khalil A, Saccone G, Rizzo G, Buca D, Liberati M, et al.Outcome of Coronavirus spectrum infections SARS, MERS, COVID 1 -19 during pregnancy: a systematic review and meta-analysis.Am J Obstet Gynecol MFM. 2020 25;2:100107. doi: 10.1016/j.ajogmf.2020.100107. Online ahead of print. CR - Liang H, Acharya G. Novel corona virus disease COVID-19 in pregnancy: What clinical recommendations to follow.Acta Obstet Gynecol Scand. 2020;99:439-442. doi: 10.1111/aogs.13836. Epub 2020 Mar 5. UR - https://dergipark.org.tr/tr/pub/yuksekihtisas/issue//1449711 L1 - https://dergipark.org.tr/tr/download/article-file/3782989 ER -