TY  - JOUR
T1  - Relationship between deep vein thrombosis and serial chest computerized tomography severity scores in COVID-19 patients
TT  - COVID-19 hastalarında derin ven trombozu ile seri toraks bilgisayarlı tomografi şiddet skorları arasındaki ilişkisi
AU  - Akman, Burcu
AU  - Kaya, Ahmet Turan
AU  - Çapraz, Mustafa
AU  - Cihangiroğlu, Mustafa
PY  - 2025
DA  - May
Y2  - 2024
DO  - 10.21673/anadoluklin.1493434
JF  - Anatolian Clinic the Journal of Medical Sciences
JO  - Anatolian Clin
PB  - Hayat Sağlık ve Sosyal Hizmetler Vakfı
WT  - DergiPark
SN  - 2149-5254
SP  - 197
EP  - 210
VL  - 30
IS  - 2
LA  - en
AB  - Aim: We aimed to evaluate risk factors for deep vein thrombosis (DVT) in the lower extremities veins in COVID-19 patients and the relationship between DVT and chest Computed Tomography severity scores (CT-SS). To our knowledge, our study is the first to investigate the relationship between the occurrence of DVT and serial chest CT-SS in COVID-19 patients.Methods: We retrospectively analyzed 131 COVID-19 patients (≥18 years) admitted to our hospital. Two radiologists examined chest CT scans and calculated CT-SS using a visual scoring system. Color Doppler ultrasounds of lower extremity veins were performed for DVT. CT Pulmonary Angiographies (CTPA) were performed on patients clinically suspected of pulmonary embolism (PE).Results: A total of 131 patients were included in our study. 71/131 (54.2%) of the patients were male. 18/131 (13.7%) patients were treated in ICU, and 18 (13.7%) patients died. 21/131 (16%) patients had DVT in their lower extremities. Chest CTA was performed in 44/131 (33.6%) patients, and PE was detected in 10/44 patients (22.7%). PE was considerably more common in patients with DVT (p = 0.009). The occurrence of DVT was significantly associated with high first chest CT-SS (p=0.002). However, there was no association between the DVT and the second and third CT-SS. Significant associations were found between the development of DVT with elevated serum D-Dimer, CRP, and fibrinogen levels (p
KW  - Computed tomography angiography
KW  - COVID-19
KW  - doppler ultrasonography
KW  - venous thrombosis
N2  - Amaç: COVID-19 hastalarında alt ekstremite venlerinde derin ven trombozu (DVT) için risk faktörlerini ve DVT ile toraks Bilgisayarlı Tomografi şiddet skorları (BT-ŞS) arasındaki ilişkiyi değerlendirmeyi amaçladık. Bildiğimiz kadarıyla, çalışmamız COVID-19 hastalarında DVT oluşumu ile seri toraks BT-ŞS arasındaki ilişkiyi araştıran ilk çalışmadır.Yöntemler: Çalışmamızda, retrospektif olarak hastanemize başvuran 131 COVID-19 hastayı (≥18 yaş) analiz ettik. İki radyolog toraks BT taramalarını inceledi ve görsel bir skorlama sistemi kullanarak BT-ŞS’ nı hesapladı. DVT için alt ekstremite damarlarının renkli Doppler ultrasonları yapıldı. Klinik olarak pulmoner emboli (PE) olduğundan şüphelenilen hastalara BT Pulmoner Anjiyografiler (BTPA) uygulandı.Bulgular: Çalışmamıza toplam 131 hasta dahil edildi. Hastaların 71/131’i (%54,2) erkekti. 18/131 (%13,7) hasta yoğun bakımda tedavi gördü ve 18 (%13,7) hasta öldü. 21/131 hastanın alt ekstremitelerinde DVT (%16) vardı. 44/131 (%33,6) hastaya toraks BTA yapıldı ve 10/44 (%22,7) hastada PE saptandı. DVT’li hastalarda PE sıklığı anlamlı olarak yüksekti (p= 0.009). DVT oluşumu, yüksek ilk göğüs BT-ŞS’si ile anlamlı şekilde ilişkiliydi (p=0.002). Ancak DVT ile ikinci ve üçüncü BT-ŞS arasında ilişki yoktu. Artmış serum D-Dimer, CRP ve fibrinojen seviyeleri ile DVT gelişimi arasında anlamlı ilişkiler bulundu (p
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UR  - https://doi.org/10.21673/anadoluklin.1493434
L1  - https://dergipark.org.tr/tr/download/article-file/3971206
ER  -