@article{article_1499578, title={The Relationship Between Lipid Profile, Oxidative Stress, and Thiol-Disulfide Levels in Healthy, Naturally Overweight and Obese Cats}, journal={Veterinary Sciences and Practices}, volume={19}, pages={148–154}, year={2024}, DOI={10.17094/vetsci.1499578}, author={Kurtdede, Efe and Taşkın, Nisa and İspir, Emre Salih and Gülendağ, Erman}, keywords={Karaciğer enzimleri, kedi, lipit metabolizması, obezite, oksidatif stres}, abstract={This study aimed to evaluate systemic inflammation, oxidative stress and lipid profile in cats that had either naturally gained excess weight or had developed obesity. The following groups were examined in the study: ten obese cats with a body condition score of (BCS) >8 (the obesity group), ten overweight cats with a BCS score of >6 (the overweight group) and ten ideal weight cats with a BCS score of 4-5 (the control group). In the cats that had either gained too much weight or had become obese, the serum AST (P < .001), albumin (P = .002) and total protein (TP) (P < .001) levels were found to be significantly higher than the values determined in the control group cats. Furthermore, blood serum high-density lipoprotein (HDL) (P = .009) and triglyceride (TG) (P < .001) levels in cats that had developed obesity were found to be significantly higher than the values defined in the control group cats. In the obese cats, serum procalcitonin (PCT), paraoxonase-1 (PON-1), total thiol, native thiol and MDA levels were found to be significantly higher than in overweight cats (P < .001). As a result, it was concluded that it would be useful for veterinarians to consider significant changes in parameters related to liver function and lipid metabolism, as well as to emphasize systemic inflammation and oxidative stress in their clinical evaluations in cats that had either naturally gained excess weight or had developed obesity.}, number={3}, publisher={Atatürk Üniversitesi}, organization={Türkiye Bilimsel ve Teknolojik Araştırma Kurumu (TÜBİTAK)}