@article{article_1509013, title={One of the Factor Associated with Etiopathogenesis of Diabetes Mellitus: Intraerythrocyte Fluid Volume}, journal={İstanbul Gelişim Üniversitesi Sağlık Bilimleri Dergisi}, pages={1130–1139}, year={2024}, DOI={10.38079/igusabder.1509013}, author={Bahtiyar, Nurten and Aydemir, Birsen and Hacıoğlu, Burcu and Sevinç Afşar, Leyla and Savaş, Gamze and Köse, Fadime and Azmamedova, İnci and Kızıler, Ali Rıza and Cinemre, Fatma Behice}, keywords={Diabetes mellitus, eritrosit içi sıvı hacmi, eritrosit indeksleri, biyokimyasal parametreler}, abstract={Aim: The aim of the present study was to investigate the levels of intraerythrocyte fluid volume, erythrocyte indices, and biochemical parameters and to evaluate the relationship between intraerythrocyte fluid volume and these parameters in patients with Diabetes Mellitus (DM) and healthy controls.
Method: The study included 42 patients with DM and 40 healthy controls. Biochemical parameters were measured using an automated analyzer. Complete blood counts were performed using an automated hematology analyzer, and intraerythrocyte fluid volumes were measured using the microcentrifugation method.
Results: Intraerythrocyte fluid volume, glycated hemoglobin (HbA1c), and glucose levels were higher in the patient group than in the control group, whereas mean corpuscular volume (MCV), potassium (K), and sodium (Na) values were lower in the patient group than in the control group. On the other hand, a negative correlation was found between intraerythrocyte fluid volume and mean corpuscular hemoglobin concentration (MCHC), magnesium (Mg), and K values in the patient group.
Conclusion: Studies findings indicated that intraerythrocyte fluid volume may be an effective hemodynamic parameter in the etiopathogenesis of DM. In line with these data, it can be suggested that intraerythrocyte fluid volume is an important factor that should be considered in monitoring the progression of the disease.}, number={24}, publisher={İstanbul Gelişim Üniversitesi}