TY  - JOUR
T1  - Evaluation of COVID-19 Patients Who Developed after COVID-19 Vaccination
TT  - COVID 19 aşısı sonrası gelişen COVID 19 hastalarının değerlendirilmesi
AU  - Karacaer, Cengiz
AU  - Kaya, Gülsüm
AU  - Özkan Oskay, Pınar
AU  - Kebabcı Mert, Nesrin
AU  - Trabzon, Şeyma
AU  - Ergenç, Zeynep
AU  - Ergenç, Hasan
AU  - Karakus, Osman
PY  - 2024
DA  - August
Y2  - 2024
DO  - 10.34084/bshr.1510840
JF  - Journal of Biotechnology and Strategic Health Research
JO  - J Biotechnol and Strategic Health Res
PB  - Deneysel, Biyoteknolojik, Klinik ve Stratejik Sağlık Araştırmaları Derneği
WT  - DergiPark
SN  - 2587-1641
SP  - 117
EP  - 124
VL  - 8
IS  - 2
LA  - en
AB  - Aim: The aim of this study is to evaluate the sociodemographic and clinical characteristics of patients with COVID-19 that developed after COVID-19 vaccination. Material and Method: The study was conducted at a state hospital between July 5 and August 5, 2021. Patients who received COVID-19 vaccine, whose SARS-CoV-2 positivity was confirmed by molecular methods, and who were hospitalized for COVID-19 were included. Sociodemographic information and clinical observation results of patients were recorded. Results: 49.09% of the patients were female and the median age was 72.00 [62.00-79.00] years. 70.45% of patients had a chronic disease and 37.27% were constantly using medication. 82.73% of patients received the CoronaVac vaccine and 8.18% received COVID-19 mRNA vaccine; 9.09% had received both vaccines. 66.82% of patients received two doses of COVID-19 vaccine, 26.82% received three doses, 5.45% received one dose and 0.91% received four doses of COVID-19 vaccine. When the infection findings at the time of admission to the hospital are evaluated, the most common symptoms in patients are dyspnea (89.55%), cough (45.45%), weakness (37.73%), malaise (22.27%) and fatigue-exhaustion. (20.00%); 95% of them had COVID-19 findings in their lung imaging reports. 99.55% of patients receive oxygen therapy; 62.73% were connected to mechanical ventilation. 91.82% of patients were receiving steroid treatment, 89.09% were receiving faviripavir treatment, and 98.64% were receiving anticoagulant; 96.82% had received antibiotic treatment. 38.64% of patients were discharged; 61.36% died. Conclusion: It has been observed that the average age of patients who contracted COVID-19 disease after the COVID-19 vaccine was high, they had a high rate of chronic disease, they were vaccinated with hight rate CoronaVac vaccine, and they received a maximum of two doses of vaccine and they did not receive a reminder dose. Mortality and morbidity can be reduced by creating successful vaccination programs as well as protective measures in the fight against COVID-19.
KW  - vaccine
KW  - COVID-19 vaccine
KW  - COVID-19 infection
KW  - patient characteristics
N2  - Amaç: Bu çalışmanın amacı, COVID-19 aşısı sonrası gelişen COVID-19 hastalarının sosyodemografik ve klinik özelliklerini değerlendirmektir.Gereç ve Yöntem: Çalışma, 5 Temmuz-5 Ağustos 2021 tarihleri arasında bir devlet hastanesinde gerçekleştirildi. SARS-CoV-2 pozitifliği moleküler yöntemlerle doğrulanan ve COVID-19 nedeniyle hastaneye yatırılan, COVID-19 aşısı yapılan hastalar dahil edildi. Hastaların sosyodemografik bilgileri ve klinik gözlem sonuçları kaydedildi.Bulgular: Hastaların %49,09'u kadındı ve ortanca yaş 72,00 [62,00-79,00] yıldı. Hastaların %70,45'inin kronik hastalığı vardı ve %37,27'si sürekli ilaç kullanıyordu. Hastaların %82,73'üne CoronaVac aşısı, %8,18'ine ise COVID-19 mRNA aşısı yapıldı; %9,09'u her iki aşıyı da almıştı. Hastaların yüzde 66,82'sine iki doz, yüzde 26,82'sine üç doz, yüzde 5,45'ine tek doz ve yüzde 0,91'ine dört doz aşı yapıldı. Hastaneye başvuru anındaki enfeksiyon bulguları değerlendirildiğinde hastalarda en sık görülen semptomlar nefes darlığı (%89,55), öksürük (%45,45), halsizlik (%37,73), kırgınlık (%22,27) ve yorgunluk-bitkinlikti. (%20,00). Hastaların %95’inin akciğer görüntüleme raporlarında COVID-19 bulguları vardı. Hastaların %99,55’i oksijen tedavisi alırken; %62,73’ü mekanik ventilasyona bağlanmıştı. Hastaların %91,82’si steroid tedavisi, %89,09’u faviripavir tedavisi, %98,64’ü antikoagülan alırken; %96,82’si antibiyotik tedavisi almıştı. Hastaların %38,64’ü taburcu olurken; %61,36’sı ex oldu.Sonuç: COVID 19 aşısı sonrası COVID 19 hastalığına yakalanan hastaların özelliklerinin yaş ortalaması yüksek olduğu, kronik hastalık varlığı, CoronaVac aşısı oldukları ve en fazla iki doz aşı olup hatırlatma dozu aşı olmadıkları görülmüştür. COVID 19 ile mücadelede korunma önlemlerinin yanında başarılı aşı programlarının oluşturulmasıyla mortalite ve morbidite azaltılabilir.
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UR  - https://doi.org/10.34084/bshr.1510840
L1  - https://dergipark.org.tr/tr/download/article-file/4046998
ER  -