TY  - JOUR
T1  - Bioactive and Anti-carcinogenic Properties of Kombucha Prepared with Aronia Melanocarpa Juice
AU  - Çalışkan, Zeynep
AU  - Yıldız, Elif
AU  - Güldaş, Metin
AU  - Gürbüz, Ozan
PY  - 2023
DA  - December
JF  - Yeni Yüzyıl Journal of Medical Sciences
JO  - JMS
PB  - İstanbul Yeni Yüzyıl Üniversitesi
WT  - DergiPark
SN  - 2687-5411
SP  - 198
EP  - 206
VL  - 4
IS  - 4
LA  - en
AB  - Aim: Polyphenolics derived from Aronia Melanocarpamay have beneficial effects in reducing the risk of several diseases, such as diabetes, cardiovascular diseases, andcancer. Kombucha is a symbiotic system comprising cultures of bacteria and yeasts known as SCOBY. It is prepared by fermenting sugar and tea leaves. In this study, weaimed to enhance the beneficial aspects of Kombucha bypreparing it using aronia juice as a fermentation substrate.Methods: The total phenolic content was measured quantitatively through the Folin-Ciocalteu method, with Gallicacid as the standard. The antioxidant capacity was determined using the ABTS and DPPH methods. Cell viabilityin colon cancer and normal fibroblasts was determinedusing the MTT assay.Results: The mean values of pH and total acidity of aroniajuice used in Kombucha production were determined as5.24±0.00 and 0.45±0.05, respectively. The total phenolic content was highest in the sample containing green teaand aronia juice. The antioxidant capacity of the samplecontaining green tea and aronia juice had the highest values in extractable (TEACABTS: 13.39 µmol Trolox/mL),hydrolyzable (TEACDPPH: 15.15 µmol Trolox/mL) andbioaccessible phenolics (TEACABTS: 4.77 µmol Trolox/mL). However, we found a decline by about 56% in theviability of colon cancer cells (HT-29) after treatment withthe Kombucha sample containing green tea and aroniajuice.Conclusion: Enrichment of Kombucha with aronia juiceis a good alternative for producing new fermented drinkswith high antioxidant capacity. Kombucha enriched witharonia juice has high total phenolic content and antioxi dant capacity. Besides, it may be considered in the contextof colon cancer prevention.
KW  - Aronia melanocarpa
KW  - Kombucha
KW  - anti-carcinogenic effect
KW  - antioxidant capacity
KW  - bioaccessibility
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UR  - https://dergipark.org.tr/tr/pub/yjms/issue//1524589
L1  - https://dergipark.org.tr/tr/download/article-file/4107436
ER  -